RAFFA, Demetrio
 Distribuzione geografica
Continente #
NA - Nord America 7.442
EU - Europa 3.798
AS - Asia 3.000
Continente sconosciuto - Info sul continente non disponibili 481
SA - Sud America 404
AF - Africa 134
OC - Oceania 5
Totale 15.264
Nazione #
US - Stati Uniti d'America 7.278
SG - Singapore 1.028
RU - Federazione Russa 887
IT - Italia 886
CN - Cina 845
FI - Finlandia 499
UA - Ucraina 325
HK - Hong Kong 312
BR - Brasile 308
DE - Germania 294
VN - Vietnam 250
PL - Polonia 189
IE - Irlanda 172
GB - Regno Unito 154
SE - Svezia 121
FR - Francia 116
JP - Giappone 101
IN - India 94
CA - Canada 86
KR - Corea 66
CI - Costa d'Avorio 55
BD - Bangladesh 50
TR - Turchia 44
IQ - Iraq 41
MX - Messico 32
AR - Argentina 30
NL - Olanda 26
BE - Belgio 22
RO - Romania 22
ZA - Sudafrica 21
UZ - Uzbekistan 19
EC - Ecuador 16
IR - Iran 15
PK - Pakistan 15
AT - Austria 14
CH - Svizzera 14
DZ - Algeria 14
ID - Indonesia 14
ES - Italia 13
PH - Filippine 13
VE - Venezuela 13
JO - Giordania 12
CO - Colombia 11
MA - Marocco 11
SA - Arabia Saudita 11
CL - Cile 10
CR - Costa Rica 10
MY - Malesia 10
NP - Nepal 9
TT - Trinidad e Tobago 9
AE - Emirati Arabi Uniti 8
CZ - Repubblica Ceca 8
EG - Egitto 8
GR - Grecia 7
PY - Paraguay 7
AL - Albania 6
JM - Giamaica 6
KE - Kenya 6
PR - Porto Rico 6
AU - Australia 5
AZ - Azerbaigian 5
LB - Libano 5
TN - Tunisia 5
KZ - Kazakistan 4
NG - Nigeria 4
PE - Perù 4
PS - Palestinian Territory 4
SN - Senegal 4
UY - Uruguay 4
BY - Bielorussia 3
EU - Europa 3
HN - Honduras 3
HU - Ungheria 3
LV - Lettonia 3
NI - Nicaragua 3
TW - Taiwan 3
AM - Armenia 2
BN - Brunei Darussalam 2
CG - Congo 2
CY - Cipro 2
IL - Israele 2
KH - Cambogia 2
LT - Lituania 2
MD - Moldavia 2
PT - Portogallo 2
QA - Qatar 2
SI - Slovenia 2
XK - ???statistics.table.value.countryCode.XK??? 2
AO - Angola 1
BG - Bulgaria 1
BH - Bahrain 1
BS - Bahamas 1
BZ - Belize 1
CU - Cuba 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
GA - Gabon 1
GE - Georgia 1
GT - Guatemala 1
Totale 14.770
Città #
Ashburn 990
Fairfield 711
Singapore 708
San Jose 478
Woodbridge 462
Chandler 400
Ann Arbor 331
Wilmington 329
Houston 311
Hong Kong 310
Seattle 285
Cambridge 270
Palermo 259
Jacksonville 173
Dublin 172
Zgierz 162
Council Bluffs 144
Beijing 137
Medford 128
Moscow 127
Nanjing 122
Dallas 116
Santa Clara 100
Tokyo 97
Des Moines 94
Boardman 85
Princeton 83
Frankfurt am Main 81
Los Angeles 81
Ho Chi Minh City 79
The Dalles 78
Altamura 74
Lauterbourg 66
Dearborn 64
New York 59
Hanoi 57
Abidjan 55
Tulsa 53
San Diego 50
Lawrence 47
Milan 47
Buffalo 45
Helsinki 35
Shenyang 34
Hefei 33
Tianjin 33
São Paulo 28
Hebei 27
Jinan 27
Venice 27
London 25
Nanchang 23
Guangzhou 21
Ottawa 21
Atlanta 20
Jiaxing 20
Orem 20
Rome 20
Zhengzhou 20
Ludwigshafen am Rhein 19
Changsha 18
Shanghai 18
Piscataway 17
Saint Petersburg 17
Seongnam 17
Toronto 17
Washington 17
Chicago 16
Columbus 16
Ningbo 16
Warsaw 16
Da Nang 15
Montreal 15
Tashkent 15
Johannesburg 14
Kumar 14
Mumbai 14
Brussels 13
Redwood City 13
Amman 12
Mexico City 12
Paris 12
Phoenix 12
Auburn Hills 11
Baghdad 11
Belo Horizonte 11
Denver 11
Izmir 11
New Delhi 11
Amsterdam 10
Brooklyn 10
Haiphong 10
Kunming 10
Poplar 10
Stockholm 10
Andover 9
Bari 9
Berlin 9
Dhaka 9
Hangzhou 9
Totale 9.490
Nome #
Discovery of a new class of sortase a transpeptidase inhibitors to tackle gram-positive pathogens: 2-(2-phenylhydrazinylidene)alkanoic acids and related derivatives 315
N-(INDAZOLYL)BENZAMIDO DERIVATIVES AS CDK1 INHIBITORS: DESIGN, SYNTHESIS, BIOLOGICAL ACTIVITY, AND MOLECULAR DOCKING STUDIES 306
4-Diazopyrazole Derivatives as Potential New Antibiofilm Agents 303
Anthranilamide-based 2-phenylcyclopropane-1-carboxamides, 1,1'-biphenyl-4-carboxamides and 1,1'-biphenyl-2-carboxamides: Synthesis biological evaluation and mechanism of action 293
2-Cinnamamido, 2-(3-phenylpropiolamido), and 2-(3-phenylpropanamido)benzamides: synthesis, antiproliferative activity, and mechanism of action 290
Comparative studies of the Pschorr reaction in the pyrazole series. Access to the new dibenzo(e,g)pyrazolo(1,5-a)(1,3)diazocine system of pharmaceutical interest 261
2-cinnamamido, 2-(3-phenylpropiolamido) and 2-(3-phenylpropanamido)benzamides: synthesis, antiproliferative activity and mechanism of action 257
Synthesis and antiproliferative activity of 3-(2-cloroethyl)-5-methyl-6-phenyl-8-(trifluoromethyl)-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4-(3H)-one 246
NEW 4-DIAZOPYRAZOLE DERIVATIVES AS POTENTIAL ANTIBIOFILM AGENTS 243
Synthesis and anti-staphylococcal activity of new 4-diazopyrazole derivatives 240
A new class of phenylhydrazinylidene derivatives as inhibitors of Staphylococcus aureus biofilm formation 240
Synthesis, antiproliferative activity, and mechanism of action of a series of 2-{[2E]-3-phenylprop-2-enoylamino}benzamides 233
SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF 3-AMINO-N-PHENYL-1H-INDAZOLE-1-CARBOXAMIDES 229
Nonclassical Pschorr and Sandmeyer Reactions in Pyrazole Series 227
The Reactivity of 4’-Substituted Spiro[Isoindole-1,3’-pyrazoles] Derivatives: Substitution/Elimination Reactions and Access to Biaryl Derivatives 227
Synthesis of alkyl-5,8-dimethyl-6-phenyl-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4(3H)-ones of pharmaceutical interest 217
SYNTHESIS AND IN VITRO ANTILEUKEMIC ACTIVITY OF NEW 4-TRIAZENOPYRAZOLE DERIVATIVES 217
Isoxazolo[3,4-d]pyridazin-7(6H)-one derivatives endowed with anti-proliferative Activity. 217
Synthesis, anti-inflammatory activity, and in vitro antitumor effect of a novel class of cyclooxygenase inhibitors: 4-(aryloyl)phenyl methyl sulfones 216
Recent advanced in bioactive systems containing pyrazole fused with a five membered heterocycle 216
Synthesis and antiproliferative activity of 3-amino-N-phenyl-1H-indazole-1-carboxamides 211
Chemical composition, cytotoxic effects, antimicrobial and antibiofilm activity of Artemisia arborescens (Vaill.) L. growing wild in the province of Agrigento, Sicily, Italy. 211
Antileukemic activity of some new 3-amino-N-phenyl-(1H)-indazole-1-carboxamide derivatives 210
Synthesis and induction of G0-G1 phase arrest with apoptosis of 3,5-dimethyl-6-phenyl-8-(trifluoromethyl)-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4(3H)-one 209
Synthesis and COX inhibition of 7-R1-8-R2-1-ethyl-3,4-dimethyl-, 4,10-dihydro-1H-pyrazolo[3,4-c][1,5]benzodiazocine-5,11-diones 208
Discovery of a New Class of Sortase A Transpeptidase Inhibitors to Tackle Gram-positive Pathogens: 2-Phenylhydrazonoalkanoic Acid Derivatives 205
New Anti-Adhesion Agents In The Development of Antivirulence Drugs 205
Synthesis of substituted 3-amino-N-phenyl-1H-indazole-1-carboxamides endowed with antiproliferative activity 204
Progettazione e sintesi di nuovi derivati 4-chinazolinonici potenziali inibitori della diidrofolato reduttasi 197
Synthesis and biological evaluation of new indazole derivatives 194
Pyrazolobenzotriazinones Derivatives as COX Inhibitors: Synthesis Biological Activity and Molecular Modeling Studies 193
CDK: LigandFit Enrichment Plot of Active Compounds in a Screening Dataset. 193
SYNTHESIS, CYTOTOXICITY, AND INHIBITORY EFFECTS ON TUBULIN POLYMERIZATION OF A NEW 3-HETEROCYCLO SUBSTITUTED 2-STYRYLQUINAZOLINONES 192
Synthesis and antileukemic activity of new 3-(5-methylisoxazol-3-yl) and 3-(pyrimidin-2-yl)-2-styrylquinazolin-4(3H)-ones. 192
Non-Classical Transformation of Benzendiazonium Hydrogen Sulfates. Access to 1,3-Dimethylisochromeno[4,3-c]pyrazol-5(1H)-one, a Potential Benzodiazepine Receptor Ligand 190
Pharmaceutical potential of synthetic and natural pyrrolomycins 190
The role of (E)-6-chloro-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-2-styrylquinazolin-4(3H)-one in the modulation of cannabinoidergic system. A pilot study 190
BENZOTRIAZINONE AND QUINAZOLINONE DERIVATIVES AS COX-INHIBITORS: COMPUTATIONAL STUDIES 189
SYNTHESIS AND ANTILEUKEMIC ACTIVITY OF NEW 3-(1-PHENYL-3-METHYLPYRAZOL-5-YL)-2-STYRYLQUINAZOLIN-4(3H)-ONES 183
Electronic ionization mass spectra of 3-(5'-(3'-methylisoxazol))- and 3-(3'-(5'-methylisoxazol)-2-styryl-4(3H)quinazolinones of pharmaceutical interest:an useful tool to distinguish the two isomeric series 177
Synthesis and antiproliferative activity of new derivatives containing the polycyclic system 5,7:7,13-dimethanopyrazolo[3,4-b]pyrazolo[3’,4’:2,3]azepino[4,5-f]azocine 176
Pirrolomicine che inibiscono la Sortasi A nelle infezioni sostenute da batteri Gram-positivi 175
Derivati policiclici con struttura complessa dotati di attività antiproliferativa 173
4-(3H)-quinazolinones N-3 substituted with a five membered heterocycle: A promising scaffold towards bioactive molecules 172
Synthesis and antifungal activity of new N-isoxazolyl-2-iodobenzamides 171
Synthesis, benzodiazepine receptor binding and molecular modelling of isochromeno[4,3-c]pyrazol-5(1H)-one derivatives 168
Sintesi di un isostero del 3,5-dimetil-6-fenil-8-(trifluorometil)-5,6-diidropirazolo[3,4-f][1,2,3,5]tetrazepin-4(3H)-one (CF3-TZP) con potenziale attività biologica 168
Synthesis and biofilm formation reduction of pyrazole-4-carboxamide derivatives in some Staphylococcus aureus strains 167
Novel 4-(3-phenylpropionamido), 4-(2-phenoxyacetamido) and 4-(cinnamamido) substituted benzamides bearing the pyrazole or indazole nucleus: synthesis, biological evaluation and mechanism of action 165
SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF TRIAZENOINDAZOLES AND TRIAZENOPYRAZOLES: A COMPARATIVE STUDY 164
Novel chemical countermeasures against staphylococcal biofilms 163
Pyrazolo[3,4-d]pyrimidine Derivatives as COX-2 Selective Inhibitors: Synthesis and Molecular Modelling Studies 162
RADICAL CYCLIZATION AND 1,5-HYDROGEN TRANSFER IN SELECTED AROMATIC DIAZONIUM SALTS 161
Phytochemical-rich extracts of Helianthemum lippii possess antimicrobial, anticancer, and antibiofilm activities 159
Synthesis and induction of G0-G1 phase arrest with apoptosis of 3,5-dimethyl-6-phenyl-8-trifluoromethyl-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4-one 158
SYNTHESIS AND BIOLOGICAL EVALUATION OF 2-PHENYL-3-[INDAZOL-3-YL]-4(3H)-QUINAZOLINONES 155
Synthesis and antiproliferative activity of a natural like glycoconjugate polycyclic compound 155
New complex polycyclic compounds: Synthesis, antiproliferative activity and mechanism of action 155
Sortase A Inhibitors: Recent Advances and Future Perspectives 154
Recent discoveries of anticancer flavonoids 152
Synthesis and anticancer activity of 3-amino-N-phenyl-1H-indazole-1-carboxamide and 1-(1H)indazol-3-yl-3-phenylureido derivatives 150
NUOVI DERIVATI 2-ACETAMMIDOBENZAMMIDICI: ATTIVITÀ ANTIPROLIFERATIVA E POSSIBILE MECCANISMO DI AZIONE 149
Synthesis and antifungal activity of new N-(1-phenil-4-carbetoxypyrazol-5-yl)-N-(indazol-3-yl)- and N-(indazol-5-yl)-2-iodobenzamides 145
Synthesis, antiproliferative activity and possible mechanism of action of novel 2-acetamidobenzamides bearing the 2-phenoxy functionality 145
Synthesis and antiproliferative activity of 3-amino-N-phenyl-1H-indazole-1-carboxamide derivatives 143
Synthesis and antirpoliferative activity of isoxazolo[3,4-d]pyridazin-7(6H)-one derivatives 142
Synthesis of New Indazol-3-yl derivatives as CDK1 inhibitors 141
Synthesis and biological evaluation of some new 2-phenylpropiolamidobenzamides as potential antagonists of the HDM2-p53 protein-protein interactions 140
Synthesis, antiproliferative activity, and mechanism of action of new benzamido derivatives 137
Synthesis and antiproliferative activities of two new analogs of tetrazepinones 135
A very promising antibiofilm activity against Candida albicans from an in vitro screening for antimicrobial, antibiofilm and antiproliferative activity of new synthesized 4-cinnamamido- and 2-phenoxyacedamido-1H-pyrazol-5-yl)benzamides 131
Sintesi e valutazione biologica di nuovi nitroderivati analoghi della pirrolomicina D attivi su Pseudomonas aeruginosa 131
Unclassical Pschorr and Sandmeyer reactions in pyrazole series 129
Synthesized benzamido derivatives exert antiproliferative effects by DNA damage and ROS generation. 126
SYNTHETIC AND BIOLOGICAL EVALUATION OF SOME NEW 2-CINNAMAMIDOBENZAMIDES AS POTENTIAL ANTAGONIST OF THE HDM2-P53 PROTEIN-PROTEIN INTERACTIONS 121
Synthesis and Antiproliferative Activity of a New Pyrazolo[3,4-f]1,2,3,5-tetrazepin-4(3H)-one Derivative 117
Synthesis and biological evaluation of new 2-{[(2E)-3-phenylprop-2-enoyl]amino}benzamides 117
Synthesis and antiproliferative activity of indazole derivatives 117
Reazioni consecutive di Pschorr e Sandmeyer non classiche in serie isossazolica. Accesso a composti di interesse farmaceutico 117
Synthesis and antioproliferative activity of new derivatives containing the policyclic sistem 5,7:7,13-dimethanopyrazolo[3,4-b]pyrazolo[3'.4':2,3]azepino[4,5-f]azocine 112
Synthesis of New Pyrazole Derivatives as Potential CDK1 Inhibitors 107
Novel Sortase A (SrtA) inhibitors interfere with the formation of staphylococcal biofilms 107
Reazioni consecutive di Pschorr e Sandmeyer non classiche in serie pirazolo-tiofenica. Accesso a composti di interesse farmaceutico 105
Unexpected synthesis by a non-classical Pschorr reaction of 3,5-dimethyl-1-phenyl-1,5-dihydro-4H-pyrazolo[4,3-c]quinolin-4-one, with binding affinity for the central benzodiazepine receptor 91
Totale 15.264
Categoria #
all - tutte 50.504
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 50.504


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022682 0 0 16 19 25 29 27 39 124 132 63 208
2022/20231.141 141 213 22 117 136 172 71 78 142 6 29 14
2023/2024550 24 73 19 102 45 115 44 17 2 10 15 84
2024/20251.365 54 84 49 134 75 33 118 57 103 133 206 319
2025/20264.906 350 127 312 316 447 694 714 535 342 707 171 191
2026/2027544 218 181 145 0 0 0 0 0 0 0 0 0
Totale 15.264