RAFFA, Demetrio
 Distribuzione geografica
Continente #
NA - Nord America 6.809
EU - Europa 3.731
AS - Asia 2.963
SA - Sud America 383
AF - Africa 133
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 4
Totale 14.028
Nazione #
US - Stati Uniti d'America 6.696
SG - Singapore 1.020
RU - Federazione Russa 887
IT - Italia 841
CN - Cina 837
FI - Finlandia 499
UA - Ucraina 323
HK - Hong Kong 311
BR - Brasile 298
DE - Germania 293
VN - Vietnam 248
PL - Polonia 188
IE - Irlanda 171
GB - Regno Unito 153
SE - Svezia 115
FR - Francia 114
JP - Giappone 101
IN - India 92
KR - Corea 66
CA - Canada 62
CI - Costa d'Avorio 55
BD - Bangladesh 43
TR - Turchia 42
IQ - Iraq 41
MX - Messico 31
AR - Argentina 30
NL - Olanda 24
BE - Belgio 22
RO - Romania 21
ZA - Sudafrica 21
UZ - Uzbekistan 19
IR - Iran 15
PK - Pakistan 15
AT - Austria 14
CH - Svizzera 14
ID - Indonesia 14
DZ - Algeria 13
EC - Ecuador 13
ES - Italia 11
JO - Giordania 11
MA - Marocco 11
SA - Arabia Saudita 11
MY - Malesia 10
PH - Filippine 10
VE - Venezuela 10
AE - Emirati Arabi Uniti 8
CL - Cile 8
CO - Colombia 8
CZ - Repubblica Ceca 8
EG - Egitto 8
NP - Nepal 8
GR - Grecia 7
PY - Paraguay 7
AL - Albania 6
KE - Kenya 6
AZ - Azerbaigian 5
CR - Costa Rica 5
LB - Libano 5
TN - Tunisia 5
AU - Australia 4
KZ - Kazakistan 4
NG - Nigeria 4
PE - Perù 4
PS - Palestinian Territory 4
SN - Senegal 4
UY - Uruguay 4
BY - Bielorussia 3
EU - Europa 3
HU - Ungheria 3
LV - Lettonia 3
TT - Trinidad e Tobago 3
TW - Taiwan 3
AM - Armenia 2
BN - Brunei Darussalam 2
CG - Congo 2
CY - Cipro 2
HN - Honduras 2
IL - Israele 2
KH - Cambogia 2
LT - Lituania 2
MD - Moldavia 2
PT - Portogallo 2
QA - Qatar 2
SI - Slovenia 2
XK - ???statistics.table.value.countryCode.XK??? 2
AO - Angola 1
BG - Bulgaria 1
BH - Bahrain 1
BS - Bahamas 1
CU - Cuba 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
GA - Gabon 1
GE - Georgia 1
GY - Guiana 1
JM - Giamaica 1
KG - Kirghizistan 1
KW - Kuwait 1
KY - Cayman, isole 1
LK - Sri Lanka 1
Totale 14.017
Città #
Ashburn 951
Fairfield 711
Singapore 701
Woodbridge 462
Chandler 400
Ann Arbor 331
Wilmington 329
Hong Kong 309
Houston 309
San Jose 300
Seattle 283
Cambridge 269
Palermo 247
Jacksonville 173
Dublin 171
Zgierz 162
Beijing 132
Medford 128
Moscow 127
Nanjing 122
Dallas 111
Tokyo 97
Des Moines 94
Santa Clara 93
Princeton 82
Frankfurt am Main 81
Ho Chi Minh City 78
Los Angeles 78
The Dalles 78
Council Bluffs 76
Altamura 74
Lauterbourg 66
Dearborn 64
Hanoi 57
Abidjan 55
New York 53
Tulsa 53
San Diego 50
Lawrence 47
Boardman 46
Buffalo 45
Milan 43
Helsinki 35
Shenyang 34
Hefei 33
Tianjin 33
Hebei 27
Jinan 27
São Paulo 27
Venice 27
London 24
Nanchang 23
Guangzhou 21
Ottawa 21
Jiaxing 20
Orem 20
Zhengzhou 20
Ludwigshafen am Rhein 19
Changsha 18
Piscataway 17
Saint Petersburg 17
Seongnam 17
Washington 17
Ningbo 16
Shanghai 16
Da Nang 15
Rome 15
Tashkent 15
Warsaw 15
Atlanta 14
Columbus 14
Johannesburg 14
Kumar 14
Mumbai 14
Brussels 13
Montreal 13
Redwood City 13
Mexico City 12
Toronto 12
Amman 11
Auburn Hills 11
Baghdad 11
Izmir 11
New Delhi 11
Paris 11
Amsterdam 10
Belo Horizonte 10
Chicago 10
Haiphong 10
Kunming 10
Poplar 10
Stockholm 10
Andover 9
Bari 9
Berlin 9
Hangzhou 9
Jeddah 9
Phoenix 9
Redondo Beach 9
Brooklyn 8
Totale 9.067
Nome #
N-(INDAZOLYL)BENZAMIDO DERIVATIVES AS CDK1 INHIBITORS: DESIGN, SYNTHESIS, BIOLOGICAL ACTIVITY, AND MOLECULAR DOCKING STUDIES 300
Discovery of a new class of sortase a transpeptidase inhibitors to tackle gram-positive pathogens: 2-(2-phenylhydrazinylidene)alkanoic acids and related derivatives 296
4-Diazopyrazole Derivatives as Potential New Antibiofilm Agents 294
2-Cinnamamido, 2-(3-phenylpropiolamido), and 2-(3-phenylpropanamido)benzamides: synthesis, antiproliferative activity, and mechanism of action 281
Anthranilamide-based 2-phenylcyclopropane-1-carboxamides, 1,1'-biphenyl-4-carboxamides and 1,1'-biphenyl-2-carboxamides: Synthesis biological evaluation and mechanism of action 281
Comparative studies of the Pschorr reaction in the pyrazole series. Access to the new dibenzo(e,g)pyrazolo(1,5-a)(1,3)diazocine system of pharmaceutical interest 256
2-cinnamamido, 2-(3-phenylpropiolamido) and 2-(3-phenylpropanamido)benzamides: synthesis, antiproliferative activity and mechanism of action 246
NEW 4-DIAZOPYRAZOLE DERIVATIVES AS POTENTIAL ANTIBIOFILM AGENTS 237
Synthesis and antiproliferative activity of 3-(2-cloroethyl)-5-methyl-6-phenyl-8-(trifluoromethyl)-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4-(3H)-one 236
Synthesis and anti-staphylococcal activity of new 4-diazopyrazole derivatives 233
A new class of phenylhydrazinylidene derivatives as inhibitors of Staphylococcus aureus biofilm formation 226
Synthesis, antiproliferative activity, and mechanism of action of a series of 2-{[2E]-3-phenylprop-2-enoylamino}benzamides 223
SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF 3-AMINO-N-PHENYL-1H-INDAZOLE-1-CARBOXAMIDES 222
The Reactivity of 4’-Substituted Spiro[Isoindole-1,3’-pyrazoles] Derivatives: Substitution/Elimination Reactions and Access to Biaryl Derivatives 221
Nonclassical Pschorr and Sandmeyer Reactions in Pyrazole Series 220
Synthesis, anti-inflammatory activity, and in vitro antitumor effect of a novel class of cyclooxygenase inhibitors: 4-(aryloyl)phenyl methyl sulfones 213
SYNTHESIS AND IN VITRO ANTILEUKEMIC ACTIVITY OF NEW 4-TRIAZENOPYRAZOLE DERIVATIVES 211
Synthesis of alkyl-5,8-dimethyl-6-phenyl-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4(3H)-ones of pharmaceutical interest 210
Synthesis and antiproliferative activity of 3-amino-N-phenyl-1H-indazole-1-carboxamides 207
Recent advanced in bioactive systems containing pyrazole fused with a five membered heterocycle 206
Synthesis and induction of G0-G1 phase arrest with apoptosis of 3,5-dimethyl-6-phenyl-8-(trifluoromethyl)-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4(3H)-one 202
Synthesis and COX inhibition of 7-R1-8-R2-1-ethyl-3,4-dimethyl-, 4,10-dihydro-1H-pyrazolo[3,4-c][1,5]benzodiazocine-5,11-diones 201
Isoxazolo[3,4-d]pyridazin-7(6H)-one derivatives endowed with anti-proliferative Activity. 200
Synthesis of substituted 3-amino-N-phenyl-1H-indazole-1-carboxamides endowed with antiproliferative activity 198
Chemical composition, cytotoxic effects, antimicrobial and antibiofilm activity of Artemisia arborescens (Vaill.) L. growing wild in the province of Agrigento, Sicily, Italy. 194
Antileukemic activity of some new 3-amino-N-phenyl-(1H)-indazole-1-carboxamide derivatives 193
New Anti-Adhesion Agents In The Development of Antivirulence Drugs 192
Discovery of a New Class of Sortase A Transpeptidase Inhibitors to Tackle Gram-positive Pathogens: 2-Phenylhydrazonoalkanoic Acid Derivatives 189
Synthesis and antileukemic activity of new 3-(5-methylisoxazol-3-yl) and 3-(pyrimidin-2-yl)-2-styrylquinazolin-4(3H)-ones. 188
Synthesis and biological evaluation of new indazole derivatives 188
SYNTHESIS, CYTOTOXICITY, AND INHIBITORY EFFECTS ON TUBULIN POLYMERIZATION OF A NEW 3-HETEROCYCLO SUBSTITUTED 2-STYRYLQUINAZOLINONES 187
Pyrazolobenzotriazinones Derivatives as COX Inhibitors: Synthesis Biological Activity and Molecular Modeling Studies 187
CDK: LigandFit Enrichment Plot of Active Compounds in a Screening Dataset. 184
Non-Classical Transformation of Benzendiazonium Hydrogen Sulfates. Access to 1,3-Dimethylisochromeno[4,3-c]pyrazol-5(1H)-one, a Potential Benzodiazepine Receptor Ligand 181
Pharmaceutical potential of synthetic and natural pyrrolomycins 181
BENZOTRIAZINONE AND QUINAZOLINONE DERIVATIVES AS COX-INHIBITORS: COMPUTATIONAL STUDIES 179
SYNTHESIS AND ANTILEUKEMIC ACTIVITY OF NEW 3-(1-PHENYL-3-METHYLPYRAZOL-5-YL)-2-STYRYLQUINAZOLIN-4(3H)-ONES 177
The role of (E)-6-chloro-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-2-styrylquinazolin-4(3H)-one in the modulation of cannabinoidergic system. A pilot study 177
Progettazione e sintesi di nuovi derivati 4-chinazolinonici potenziali inibitori della diidrofolato reduttasi 176
Electronic ionization mass spectra of 3-(5'-(3'-methylisoxazol))- and 3-(3'-(5'-methylisoxazol)-2-styryl-4(3H)quinazolinones of pharmaceutical interest:an useful tool to distinguish the two isomeric series 168
Synthesis and antiproliferative activity of new derivatives containing the polycyclic system 5,7:7,13-dimethanopyrazolo[3,4-b]pyrazolo[3’,4’:2,3]azepino[4,5-f]azocine 166
Derivati policiclici con struttura complessa dotati di attività antiproliferativa 162
SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF TRIAZENOINDAZOLES AND TRIAZENOPYRAZOLES: A COMPARATIVE STUDY 161
Synthesis and antifungal activity of new N-isoxazolyl-2-iodobenzamides 161
Synthesis, benzodiazepine receptor binding and molecular modelling of isochromeno[4,3-c]pyrazol-5(1H)-one derivatives 160
Synthesis and biofilm formation reduction of pyrazole-4-carboxamide derivatives in some Staphylococcus aureus strains 160
Pirrolomicine che inibiscono la Sortasi A nelle infezioni sostenute da batteri Gram-positivi 160
4-(3H)-quinazolinones N-3 substituted with a five membered heterocycle: A promising scaffold towards bioactive molecules 160
Sintesi di un isostero del 3,5-dimetil-6-fenil-8-(trifluorometil)-5,6-diidropirazolo[3,4-f][1,2,3,5]tetrazepin-4(3H)-one (CF3-TZP) con potenziale attività biologica 158
RADICAL CYCLIZATION AND 1,5-HYDROGEN TRANSFER IN SELECTED AROMATIC DIAZONIUM SALTS 157
Novel 4-(3-phenylpropionamido), 4-(2-phenoxyacetamido) and 4-(cinnamamido) substituted benzamides bearing the pyrazole or indazole nucleus: synthesis, biological evaluation and mechanism of action 157
Pyrazolo[3,4-d]pyrimidine Derivatives as COX-2 Selective Inhibitors: Synthesis and Molecular Modelling Studies 154
Novel chemical countermeasures against staphylococcal biofilms 154
Synthesis and antiproliferative activity of a natural like glycoconjugate polycyclic compound 150
Synthesis and induction of G0-G1 phase arrest with apoptosis of 3,5-dimethyl-6-phenyl-8-trifluoromethyl-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4-one 149
Phytochemical-rich extracts of Helianthemum lippii possess antimicrobial, anticancer, and antibiofilm activities 149
Recent discoveries of anticancer flavonoids 147
Sortase A Inhibitors: Recent Advances and Future Perspectives 146
SYNTHESIS AND BIOLOGICAL EVALUATION OF 2-PHENYL-3-[INDAZOL-3-YL]-4(3H)-QUINAZOLINONES 144
New complex polycyclic compounds: Synthesis, antiproliferative activity and mechanism of action 144
Synthesis and antifungal activity of new N-(1-phenil-4-carbetoxypyrazol-5-yl)-N-(indazol-3-yl)- and N-(indazol-5-yl)-2-iodobenzamides 141
Synthesis and anticancer activity of 3-amino-N-phenyl-1H-indazole-1-carboxamide and 1-(1H)indazol-3-yl-3-phenylureido derivatives 140
Synthesis, antiproliferative activity and possible mechanism of action of novel 2-acetamidobenzamides bearing the 2-phenoxy functionality 137
Synthesis and antiproliferative activity of 3-amino-N-phenyl-1H-indazole-1-carboxamide derivatives 135
Synthesis and biological evaluation of some new 2-phenylpropiolamidobenzamides as potential antagonists of the HDM2-p53 protein-protein interactions 132
NUOVI DERIVATI 2-ACETAMMIDOBENZAMMIDICI: ATTIVITÀ ANTIPROLIFERATIVA E POSSIBILE MECCANISMO DI AZIONE 131
Synthesis of New Indazol-3-yl derivatives as CDK1 inhibitors 130
Synthesis and antirpoliferative activity of isoxazolo[3,4-d]pyridazin-7(6H)-one derivatives 130
Synthesis, antiproliferative activity, and mechanism of action of new benzamido derivatives 129
Synthesis and antiproliferative activities of two new analogs of tetrazepinones 127
A very promising antibiofilm activity against Candida albicans from an in vitro screening for antimicrobial, antibiofilm and antiproliferative activity of new synthesized 4-cinnamamido- and 2-phenoxyacedamido-1H-pyrazol-5-yl)benzamides 125
Unclassical Pschorr and Sandmeyer reactions in pyrazole series 124
Reazioni consecutive di Pschorr e Sandmeyer non classiche in serie isossazolica. Accesso a composti di interesse farmaceutico 114
Synthesized benzamido derivatives exert antiproliferative effects by DNA damage and ROS generation. 114
Sintesi e valutazione biologica di nuovi nitroderivati analoghi della pirrolomicina D attivi su Pseudomonas aeruginosa 112
Synthesis and Antiproliferative Activity of a New Pyrazolo[3,4-f]1,2,3,5-tetrazepin-4(3H)-one Derivative 111
Synthesis and antiproliferative activity of indazole derivatives 110
SYNTHETIC AND BIOLOGICAL EVALUATION OF SOME NEW 2-CINNAMAMIDOBENZAMIDES AS POTENTIAL ANTAGONIST OF THE HDM2-P53 PROTEIN-PROTEIN INTERACTIONS 109
Synthesis and biological evaluation of new 2-{[(2E)-3-phenylprop-2-enoyl]amino}benzamides 108
Synthesis and antioproliferative activity of new derivatives containing the policyclic sistem 5,7:7,13-dimethanopyrazolo[3,4-b]pyrazolo[3'.4':2,3]azepino[4,5-f]azocine 106
Synthesis of New Pyrazole Derivatives as Potential CDK1 Inhibitors 100
Novel Sortase A (SrtA) inhibitors interfere with the formation of staphylococcal biofilms 99
Reazioni consecutive di Pschorr e Sandmeyer non classiche in serie pirazolo-tiofenica. Accesso a composti di interesse farmaceutico 98
Unexpected synthesis by a non-classical Pschorr reaction of 3,5-dimethyl-1-phenyl-1,5-dihydro-4H-pyrazolo[4,3-c]quinolin-4-one, with binding affinity for the central benzodiazepine receptor 82
Totale 14.504
Categoria #
all - tutte 46.995
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.995


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021217 0 0 0 0 0 0 0 0 0 0 95 122
2021/2022992 74 236 16 19 25 29 27 39 124 132 63 208
2022/20231.141 141 213 22 117 136 172 71 78 142 6 29 14
2023/2024550 24 73 19 102 45 115 44 17 2 10 15 84
2024/20251.365 54 84 49 134 75 33 118 57 103 133 206 319
2025/20264.690 350 127 312 316 447 694 714 535 342 707 146 0
Totale 14.504