Several new 2-cinnamamido, 2-(3-phenylpropiolamido) and 2-(3-phenylpropanamido)benzamides were synthesized by stirring in pyridine the opportune acid chlorides with the appropriate anthranilamide derivatives. Some of the synthesized compounds were evaluated for their in vitro antiproliferative activity against a panel of 5 human cell lines (K562 human chronic myelogenous leukemia cells, MCF-7 breast cancer cells, HTC-116 and HT26 colon cancer cells and NCI H460 non-small cell lung cancer cells).
Raffa, D., Maggio, B., Plescia, F., Cascioferro, S., Raimondi, M., Cusimano, M., et al. (2013). 2-cinnamamido, 2-(3-phenylpropiolamido) and 2-(3-phenylpropanamido)benzamides: synthesis, antiproliferative activity and mechanism of action. In Book of Abstracts of 21th National Meeting on Medicinal Chemistry (pp.111-111).
Autori: | Raffa, D.; Maggio, B.; Plescia, F.; Cascioferro, S.; Raimondi, M.; Cusimano, M.; Schillaci, D.; Daidone, G.; Amico, G.; Carollo, C.; Conaldi, P. | |
Titolo: | 2-cinnamamido, 2-(3-phenylpropiolamido) and 2-(3-phenylpropanamido)benzamides: synthesis, antiproliferative activity and mechanism of action | |
Settore Scientifico Disciplinare: | Settore CHIM/08 - Chimica Farmaceutica Settore BIO/19 - Microbiologia Generale | |
Data di creazione: | 2012-07 | |
Nome del convegno: | 21th National Meeting on Medicinal Chemistry | |
Luogo del convegno: | Palermo | |
Anno del convegno: | 17-20 luglio 2012 | |
Data di pubblicazione: | 2013 | |
Numero di pagine: | 1 | |
Citazione: | Raffa, D., Maggio, B., Plescia, F., Cascioferro, S., Raimondi, M., Cusimano, M., et al. (2013). 2-cinnamamido, 2-(3-phenylpropiolamido) and 2-(3-phenylpropanamido)benzamides: synthesis, antiproliferative activity and mechanism of action. In Book of Abstracts of 21th National Meeting on Medicinal Chemistry (pp.111-111). | |
Tipologia: | 0 - Proceedings (TIPOLOGIA NON ATTIVA) | |
Appare nelle tipologie: | 0 - Proceedings (TIPOLOGIA NON ATTIVA) |
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