N-Isoxazolyl-2-iodobenzamides 3 and 9, with a benodanil-like structure, were synthesized by refluxing in acetic acid the corresponding benzotriazinones 2 and 8 with potassium iodide for 1 h with the aim to ascertain if they were active as fungicides against Phytophthora citricola Saw., Botrytis cinerea Pers., Rhizoctonia sp. and Alternaria sp. Among the tested iodo derivatives, compounds 3b and 9a possess interesting activities against the aforesaid fungal strains in several cases similar to that of benodanil I taken as reference drug.

Raffa, D., Daidone, G., Maggio, B., Schillaci, D., Plescia, F., Torta, L. (1999). Synthesis and antifungal activity of new N-isoxazolyl-2-iodobenzamides. IL FARMACO, 54(1-2), 90-94 [10.1016/S0014-827X(98)00108-6].

Synthesis and antifungal activity of new N-isoxazolyl-2-iodobenzamides

RAFFA, Demetrio;DAIDONE, Giuseppe;MAGGIO, Benedetta;SCHILLACI, Domenico;PLESCIA, Fabiana;TORTA, Livio
1999-01-01

Abstract

N-Isoxazolyl-2-iodobenzamides 3 and 9, with a benodanil-like structure, were synthesized by refluxing in acetic acid the corresponding benzotriazinones 2 and 8 with potassium iodide for 1 h with the aim to ascertain if they were active as fungicides against Phytophthora citricola Saw., Botrytis cinerea Pers., Rhizoctonia sp. and Alternaria sp. Among the tested iodo derivatives, compounds 3b and 9a possess interesting activities against the aforesaid fungal strains in several cases similar to that of benodanil I taken as reference drug.
Settore CHIM/08 - Chimica Farmaceutica
Raffa, D., Daidone, G., Maggio, B., Schillaci, D., Plescia, F., Torta, L. (1999). Synthesis and antifungal activity of new N-isoxazolyl-2-iodobenzamides. IL FARMACO, 54(1-2), 90-94 [10.1016/S0014-827X(98)00108-6].
File in questo prodotto:
File Dimensione Formato  
Il Farmaco 57 (2002) 183-187.pdf

Solo gestori archvio

Dimensione 527.64 kB
Formato Adobe PDF
527.64 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/146161
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 28
  • ???jsp.display-item.citation.isi??? 24
social impact