Archivio istituzionale della ricerca dell'Università degli Studi di Palermo

LAURIA, Antonino
 Distribuzione geografica
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Continente #
NA - Nord America 15.991
EU - Europa 10.097
AS - Asia 7.869
SA - Sud America 1.195
AF - Africa 336
OC - Oceania 23
Continente sconosciuto - Info sul continente non disponibili 16
Totale 35.527
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Nazione #
US - Stati Uniti d'America 15.674
SG - Singapore 2.591
IT - Italia 2.334
RU - Federazione Russa 2.224
CN - Cina 2.153
FI - Finlandia 1.038
DE - Germania 1.033
BR - Brasile 900
UA - Ucraina 885
HK - Hong Kong 781
VN - Vietnam 718
GB - Regno Unito 460
PL - Polonia 458
IE - Irlanda 409
SE - Svezia 387
FR - Francia 354
JP - Giappone 329
BD - Bangladesh 278
IN - India 251
CA - Canada 146
KR - Corea 146
CI - Costa d'Avorio 132
NL - Olanda 118
AR - Argentina 110
PK - Pakistan 99
BE - Belgio 83
MX - Messico 79
IQ - Iraq 78
RO - Romania 59
ZA - Sudafrica 58
TR - Turchia 57
ES - Italia 54
CZ - Repubblica Ceca 46
VE - Venezuela 46
AT - Austria 42
EC - Ecuador 40
MY - Malesia 40
SA - Arabia Saudita 37
UZ - Uzbekistan 36
ID - Indonesia 35
IR - Iran 33
EG - Egitto 29
CL - Cile 28
JO - Giordania 28
MA - Marocco 28
NP - Nepal 22
DZ - Algeria 21
JM - Giamaica 21
AE - Emirati Arabi Uniti 20
CO - Colombia 20
PY - Paraguay 20
AU - Australia 19
CR - Costa Rica 17
CH - Svizzera 16
GR - Grecia 16
KE - Kenya 16
PE - Perù 15
AZ - Azerbaigian 14
LB - Libano 14
TH - Thailandia 14
BH - Bahrain 13
EU - Europa 12
PH - Filippine 12
LT - Lituania 11
ET - Etiopia 10
PA - Panama 10
TN - Tunisia 10
AL - Albania 9
BY - Bielorussia 8
HR - Croazia 8
IL - Israele 8
TW - Taiwan 8
BG - Bulgaria 7
GT - Guatemala 7
OM - Oman 7
UY - Uruguay 7
BO - Bolivia 6
DK - Danimarca 6
DO - Repubblica Dominicana 6
HN - Honduras 6
QA - Qatar 6
RS - Serbia 6
SN - Senegal 6
BB - Barbados 5
HU - Ungheria 5
KZ - Kazakistan 5
MD - Moldavia 5
SV - El Salvador 5
GE - Georgia 4
GH - Ghana 4
KG - Kirghizistan 4
KW - Kuwait 4
NG - Nigeria 4
TT - Trinidad e Tobago 4
AF - Afghanistan, Repubblica islamica di 3
AM - Armenia 3
AO - Angola 3
BZ - Belize 3
MK - Macedonia 3
MN - Mongolia 3
Totale 35.465
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Città #
Ashburn 1.826
Singapore 1.712
Fairfield 1.301
San Jose 1.077
Ann Arbor 931
Chandler 826
Dallas 826
Woodbridge 812
Hong Kong 747
Palermo 680
Wilmington 645
Houston 625
Seattle 517
Jacksonville 454
Cambridge 439
Zgierz 423
Dublin 407
Tokyo 319
Beijing 305
Moscow 305
Medford 273
Nanjing 256
Santa Clara 242
Council Bluffs 241
Frankfurt am Main 241
Ho Chi Minh City 232
Los Angeles 204
Boardman 200
Lauterbourg 188
New York 186
Princeton 185
Des Moines 169
Tulsa 168
Hanoi 161
Hefei 158
Abidjan 132
Milan 129
Dearborn 126
Buffalo 113
Altamura 101
Chicago 96
Jinan 93
Rome 91
San Diego 89
Helsinki 84
Lawrence 84
Shenyang 78
Brussels 77
Nanchang 73
Hebei 72
São Paulo 70
Changsha 68
London 68
Tianjin 65
Ludwigshafen am Rhein 63
The Dalles 62
Munich 57
Orem 53
Amsterdam 52
Atlanta 41
Columbus 41
Zhengzhou 41
Seongnam 40
Jiaxing 39
Brno 38
Saint Petersburg 37
Da Nang 36
Berlin 35
Guangzhou 35
Aversa 34
Chennai 34
Haiphong 33
Ottawa 32
Brooklyn 31
Montreal 31
Johannesburg 30
Auburn Hills 29
San Mateo 29
Mumbai 28
Baghdad 27
Belo Horizonte 27
Faisalabad 27
Redwood City 27
Amman 26
Denver 26
Taizhou 26
Washington 26
Kilburn 25
Lahore 25
Phoenix 25
Warsaw 25
City of London 24
Hangzhou 24
Nuremberg 24
Rio de Janeiro 24
Toronto 24
Naples 23
Cardiff 22
Dhaka 22
Ningbo 22
Totale 21.492
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Nome #
1,2,3-Triazole in Heterocyclic Compounds, Endowed with Biological Activity, through 1,3-Dipolar Cycloadditions 1.223
1,2-Dihydropyrazole[1,2-a]benzo[1,2,4]triazine-3-one: deaza analogue tricyclic scaffold with valuable antiproliferative activity 338
1-Methyl-3H-pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-ones. Design, Synthesis, and Biological Activity of New Antitumor Agents 323
DRUDIT: Web-based DRUgs DIscovery Tools to design small molecules as modulators of biological targets 315
1,3-Dipolar cycloaddition in the synthesis of a new potential DNA-intercalating agent: indolo[3,2-e]pyrrolo[1,2-c]triazolo[1,5-a]pyrimidine 298
In vitro and in silico studies of polycondensed diazine systems as anti-parasitic agents 289
A Multivariate Analysis of HIV-1 Protease Inhibitors and Resistance Induced by Mutation 280
Design, synthesis, and biological evaluation of a new class of benzo[b]furan derivatives as antiproliferative agents, with in silico predicted antitubulin activity 280
Lead optimization through VLAK protocol: New annelated pyrrolo-pyrimidine derivatives as antitumor agents 279
1,3-Dipolar cycloadditions in the synthesis of annelated diazines: design of new scaffolds for anticancer and antimicrobial agents 274
Annelated Pyrrolo-pyrimidines from Amino-cyanopyrroles and BMMAs as Leads for New DNA-interactive Ring Systems 273
Heterocyclic Scaffolds for the Treatment of Alzheimer's Disease 264
Curcumin-like compounds designed to modify amyloid beta peptide aggregation patterns 264
3D-QSAR Pharmacophore Modeling and in Silico Screening of new Bcl-xl Inhibitors 261
Pirazolo[3,4-d][1,2,3]triazolo[1,5-a]pirimidina: accesso sintetico tramite cicloaddizioni 1,3-dipolari e riarrangiamento di Dimroth 248
Pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine: a new ring system through Dimroth rearrangement 248
Hsp60, a novel target for antitumor therapy: Structure-function features and prospective drugs design 246
Antiproliferative activity of Pyrrolo[3,2-c]quinoline derivatives 242
A3 adenosine receptor: Homology modeling and 3D-QSAR studies 239
A human CCT5 gene mutation causing distal neuropathy impairs hexadecamer assembly in an archaeal model 237
Drugs Polypharmacology by In Silico Methods: New Opportunities in Drug Discovery 237
Design, synthesis, and biological evaluation of pyridothienotriazolopyrimidine derivatives as new HSP90 inhibitors 236
A multivariate analysis on HIV-1 protease inhibitors and resistance induced by mutation 235
A multivariate analysis on non-nucleoside HIV-1 reverse transcriptase inhibitors and resistance induced by mutation 235
DNA minor groove binders: an overview on molecular modeling and QSAR approaches 233
A General Treatment of Solubility. 3. Principal Component Analysis (PCA) of the Solubilities of Diverse Solutes in Diverse Solvents 229
COVALENT INHIBITION IN TRIPLE-NEGATIVE BREAST CANCER: DESIGN, SYNTHESIS AND BIOLOGICAL PROFILING OF ACRYLAMIDE-BASED QUINOLINES 228
Docking and synthesis of pyrrolopyrimidodiazepinone derivatives (PPDs) and their precursors: new scaffolds for DNA-interacting agents 227
Molecular Dynamics studies on Mdm2 complexes: an analysis of the inhibitor influence 226
An Unexpected Dimroth Rearrangement Leading to Annelated Thieno[3,2-d][1,2,3]triazolo[1,5-a]pyrimidines with Potent Antitumor Activity 226
Does ligand symmetry play a role in the stabilization of DNA g-quadruplex host-guest complexes? 226
Synthesis and biological activities of a new class of heat shock protein 90 inhibitors, designed by energy-based pharmacophore virtual screening 225
Receptor-guided 3D-QSAR approach for the discovery of c-kit tyrosine kinase inhibitors 223
Design and Synthesis of 4-Substituted Indolo[3,2-e][1,2,3]triazolo[1,5-a]pyrimidine Derivatives with Antitumor Activity 222
Nickel(II), copper(II) and zinc(II) metallo-intercalators: structural details of the DNA-binding by a combined experimental and computational investigation 219
Molecular dynamics studies on HIV-1 protease: a comparison of the flap motions between wild type protease and the M46I/G51D double mutant 217
MADoSPRO: a new Approach to Molecular Modelling Studies on a Series of DNA Minor Groove Binders 217
Molecular modelling and QSAR in the discovery of HIV-1 integrase inhibitors 217
G-quadruplex vs. duplex-DNA binding of nickel(II) and zinc(II) Schiff base complexes 217
A QSAR study investigating the potential anti-HIV-1 effect of some Acyclovir and Ganciclovir analogs 216
Inside the Hsp90 inhibitors binding mode through induced fit docking 216
A3 Adenosine Receptor: homology modeling and 3D-QSAR studies 216
A synthetic approach to new polycyclic ring system of biologial interest through domino reaction: indolo[2,3-e][1,2,3]triazolo[1,5-a]pyrimidine 215
Reactivity of asymmetric benzo-condensed diazines with nitrilimine dipoles in the 1,3-dipolar cycloaddition reactions 213
Bis-1,2,4-triazolo[4,3-a:3',4'-c]quinoxalines of pharmaceutical interest from 1,3-dipolar cycloaddition 212
ISOINDOLO[2,1-C]BENZO[1,2,4]TRIAZINES: A NEW RING SYSTEM WITH ANTIPROLIFERATIVE ACTIVITY 210
2,5-bis(3'-Indolyl)thiophenes, Analogues of Marine Alkaloid Nortopsentin. 207
Sintesi di Nuovi Derivati del Sistema Triciclico Pirazolo[3,4-d][1,2,3]triazolo[1,5-a]pirimidinico DNA interattivi 207
Molecular Docking approach on the Topoisomerase I inhibitors series included in the NCI anti-cancer agents mechanism database 206
Theoretical Determination of the pK a Values of Betalamic Acid Related to the Free Radical Scavenger Capacity: Comparison Between Empirical and Quantum Chemical Methods 204
Nuovi inibitori di Aurora chinasi A come target biologico coinvolto nei processi carcinogenici 202
Melatonin reduces inflammatory response in human intestinal epithelial cells stimulated by interleukin-1β 200
Molecular Modelling on Leptin and the Ob Receptor as anti-obesity target 198
Pharmacophore modelling as useful tool in the lead compounds identification and optimization 195
2-OXO-[1,4]OXAZINO[3,2-E]INDOLE: A NEW RING SYSTEM WITH POTENTIAL PHOTOBIOLOGICAL PROPERTIES 194
Combined use of PCA and QSAR/QSPR to predict the drugs mechanism of action. An application to the NCI ACAM Database 193
Docking of indolo- and pyrrolo-pyrimidines to DNA. New DNA-interactive polycycles from amino-indoles/pyrroles and BMMA. 192
A convenient synthesis of cycloadduct bis-1,2,4-triazolo[4,3-a:3’,4’-c]quinoxalines by 1,3-dipolar cycloaddition 189
Study of the role of “gatekeeper” mutations V654A and T670I of c-kit kinase in the interaction with inhibitors by means mixed molecular dynamics/docking approach 188
Design and synthesis of high affinity compounds for the Hsp60 expression control in carcinogenic processes 188
The interaction of Schiff Base complexes of nickel(II) and zinc(II) with duplex and G-quadruplex DNA 187
In-silico screening of new potential Bcl-2/Bcl-xl inhibitors as apoptosis modulators 187
Synthesis and Antiproliferative Activity of [1,2,3,5]tetrazino[5,4-a]indoles, a New Class of Azolo-tetrazinones 186
Synthesis, antiproliferative activity, and in silico insights of new 3-benzoylamino-benzo[ b ]thiophene derivatives 186
New benzothieno[3,2-d]-1,2,3-triazines with antiproliferative activity: Synthesis, spectroscopic studies, and biological activity 185
Exploring the anticancer potential of pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-one derivatives: The effect on apoptosis induction, cell cycle and proliferation 185
PROGETTAZIONE, SINTESI E VALUTAZIONE BIOLOGICA DI NUOVI INIBITORI DI HSP90 184
Study of Reactivity in the 1,3-Dipolar Cycloaddition Reactions Leading to New Triazolopyrrolopyrazine Ring Systems 183
A novel in silico approach for identifying multi-target JAK/STAT inhibitors as anticancer agents 182
Benzothieno-triazolo-pyrimidine: a new class of potential DNA-binders 182
Synthesis and antiproliferative activity of Naphtalenyl substituted 1,2-dihydropyrazol-5-one and related fused tetrazine 182
IKK-beta inhibitors: An analysis of drug–receptor interaction by using Molecular Docking and Pharmacophore 3D-QSAR approaches 180
The Repurposing of Old Drugs or Unsuccessful Lead Compounds by in Silico Approaches: New Advances and Perspectives 179
Principal component analysis on molecular descriptors as an alternative point of view in the search of new Hsp90 inhibitors 178
IN THE SEARCH OF LEPTIN AGONISTS AS ANTI-OBESITY DRUGS: PROTEIN/PROTEIN DOCKING, MOLECULAR DYNAMICS, AND VIRTUAL SCREENING 178
Bis-1,2,4-triazolo[4,3-a:3’,4’-c]quinoxalines of pharmaceutical interest from 1,3-dipolar cycloaddition 177
Kinase Inhibitors in Multitargeted Cancer Therapy 177
SYNTHESIS AND PHOTOCHEMIOTHERAPEUTIC ACTIVITY OF THIOPYRANO[2,3-E]INDOL-2-ONES 176
Intercalation of daunomycin into stacked DNA base pairs. DFT study of an anticancer drug 176
New annelated thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidines, with potent anticancer activity, designed through VLAK protocol 176
In silico, spectroscopic, and biological insights on annelated pyrrolo[3,2-e]pyrimidines with antiproliferative activity 176
Sintesi di Oligopeptidi Pirrolici Isomeri della Distamicina e della Netropsina 175
DERIVATI TIENO[3,2-d]-1,2,3-TRIAZIN-4(3H)ONI ANELLATI:UNA NUOVA CLASSE DI INIBITORI DI AURORA CHINASI A 175
SYNTHESIS AND EVALUATION OF CURCUMIN ANALOGUES AS NEURO-PROTECTIVE AGENTS FOR THE ALZHEIMER'S DISEASE 175
DNA-binding of nickel(II), copper(II) and zinc(II) complexes: structure-affinity relationships 174
Zinc complexes as fluorescent chemosensors for nucleic acids: New perspectives for a "boring" element 174
Reattività di diazine benzocondensate asimmetriche nelle reazioni di cicloaddizione 1,3-dipolare con dipoli nitriliminici 173
Bcl-2 come target di farmaci antitumorali modulatori dell'apoptosi 173
Antiproliferative Activity Predictor: A New Reliable In Silico Tool for Drug Response Prediction against NCI60 Panel 172
Sintesi di derivati tetraidrobis-triazolochinossalinici e di nuovi sistemi triazolopirrolopirazinici di interesse biologico mediante cicloaddizioni 1,3-dipolari 170
Antiproliferative properties and g-quadruplex-binding of symmetrical naphtho[1,2-b:8,7-b’]dithiophene derivatives 169
Innovative In Silico Method for Discovering Multi-Target JAK/STAT Inhibitors as Potential Anticancer Therapies 167
Sintesi ed Attivita’ Fotobiologica di Tiopirano[2,3-c]indol-2-oni 166
The dimer-monomer equilibrium of SARS-CoV-2 main protease is affected by small molecule inhibitors 166
In silico lead optimization and synthesis of a new series of thieno[3,2-c]quinoline with antiproliferative activity on RET-dependent medullary thyroid cancer cells 165
NiII, and ZnII Schiff Base Complexes: Telomeric G-quadruplex Stabilizers 165
DOCKING AND MULTIVARIATE METHODS TO EXPLORE HIV-1 DRUG-RESISTANCE: A COMPARATIVE ANALYSIS 164
DA-Phen, a new dopamine aminoacid conjugate: in vivo testing and molecular modeling as dopaminergic modulator 164
Identification of biological targets through the correlation between cell line chemosensitivity and protein expression pattern 164
LOOKING FOR NEW HSP-90 INHIBITORS THROUGH A MOLECULAR DOCKING/PHARMACOPHORE APPROACH 163
Totale 21.993
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Categoria #
all - tutte 114.096
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 114.096
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.433 229 506 69 107 38 75 128 99 259 313 137 473
2022/20232.639 312 367 61 256 318 466 139 197 304 68 110 41
2023/20241.525 81 192 95 142 114 244 202 56 28 54 52 265
2024/20253.792 184 180 235 304 147 147 319 291 311 375 431 868
2025/202614.025 755 592 1.289 1.001 1.157 1.769 2.028 1.421 949 1.818 596 650
2026/2027383 383 0 0 0 0 0 0 0 0 0 0 0
Totale 36.372