The title indolo-triazolo-pyrimidines were obtained from 3-azidoindoles and can be used as models for the design of DNA-interactive compounds. Hetero-domino reaction of azidoindoles/pyrroles and acetonitriles constitutes the synthetic entry to annelated 1,2,3-triazolo[1,5-a]pyrimidines.
LAURIA A, PATELLA C, DIANA P, BARRAJA P, MONTALBANO A, CIRRINCIONE G, et al. (2006). A synthetic approach to new polycyclic ring system of biologial interest through domino reaction: indolo[2,3-e][1,2,3]triazolo[1,5-a]pyrimidine. TETRAHEDRON LETTERS, 47(13), 2187-2190 [10.1016/j.tetlet.2006.01.112].
A synthetic approach to new polycyclic ring system of biologial interest through domino reaction: indolo[2,3-e][1,2,3]triazolo[1,5-a]pyrimidine
LAURIA, Antonino;PATELLA, Chiara;DIANA, Patrizia;BARRAJA, Paola;MONTALBANO, Alessandra;CIRRINCIONE, Girolamo;DATTOLO, Gaetano;ALMERICO, Anna Maria
2006-01-01
Abstract
The title indolo-triazolo-pyrimidines were obtained from 3-azidoindoles and can be used as models for the design of DNA-interactive compounds. Hetero-domino reaction of azidoindoles/pyrroles and acetonitriles constitutes the synthetic entry to annelated 1,2,3-triazolo[1,5-a]pyrimidines.
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