Archivio istituzionale della ricerca dell'Università degli Studi di Palermo

D'ALESSANDRO, Natale
 Distribuzione geografica
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Continente #
NA - Nord America 9.489
EU - Europa 6.409
AS - Asia 4.806
SA - Sud America 795
AF - Africa 140
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 2
Totale 21.648
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Nazione #
US - Stati Uniti d'America 9.355
SG - Singapore 1.660
IT - Italia 1.649
RU - Federazione Russa 1.361
CN - Cina 1.234
FI - Finlandia 748
UA - Ucraina 733
BR - Brasile 651
HK - Hong Kong 546
DE - Germania 472
VN - Vietnam 443
PL - Polonia 294
IE - Irlanda 283
GB - Regno Unito 261
FR - Francia 248
JP - Giappone 210
SE - Svezia 118
IN - India 108
TR - Turchia 105
BD - Bangladesh 103
KR - Corea 92
CA - Canada 69
IQ - Iraq 58
AR - Argentina 50
NL - Olanda 42
MX - Messico 40
CI - Costa d'Avorio 38
BE - Belgio 37
IR - Iran 36
RO - Romania 31
PK - Pakistan 29
VE - Venezuela 29
ZA - Sudafrica 27
MA - Marocco 24
AT - Austria 23
UZ - Uzbekistan 22
ES - Italia 21
MY - Malesia 20
EC - Ecuador 19
SA - Arabia Saudita 19
ID - Indonesia 17
CH - Svizzera 15
PH - Filippine 15
AL - Albania 14
CZ - Repubblica Ceca 12
EG - Egitto 12
TN - Tunisia 11
AE - Emirati Arabi Uniti 10
AZ - Azerbaigian 10
CL - Cile 10
SK - Slovacchia (Repubblica Slovacca) 10
CO - Colombia 9
NP - Nepal 9
PY - Paraguay 9
JO - Giordania 8
LB - Libano 8
LT - Lituania 8
BG - Bulgaria 7
KE - Kenya 7
PE - Perù 7
BH - Bahrain 6
DZ - Algeria 6
EU - Europa 6
GR - Grecia 5
JM - Giamaica 5
OM - Oman 5
UY - Uruguay 5
BO - Bolivia 4
GE - Georgia 4
HN - Honduras 4
HU - Ungheria 4
IL - Israele 4
KZ - Kazakistan 4
PS - Palestinian Territory 4
AM - Armenia 3
MM - Myanmar 3
SN - Senegal 3
TH - Thailandia 3
TT - Trinidad e Tobago 3
AO - Angola 2
AU - Australia 2
BB - Barbados 2
CR - Costa Rica 2
DK - Danimarca 2
EE - Estonia 2
ET - Etiopia 2
GH - Ghana 2
GY - Guiana 2
HR - Croazia 2
KH - Cambogia 2
LY - Libia 2
MN - Mongolia 2
NG - Nigeria 2
NI - Nicaragua 2
PR - Porto Rico 2
RS - Serbia 2
BM - Bermuda 1
BY - Bielorussia 1
DO - Repubblica Dominicana 1
GA - Gabon 1
Totale 21.635
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Città #
Ashburn 1.098
Singapore 1.087
Fairfield 776
San Jose 622
Chandler 581
Hong Kong 535
Woodbridge 469
Ann Arbor 430
Houston 415
Wilmington 410
Jacksonville 388
Seattle 295
Dublin 280
Palermo 269
Zgierz 265
Cambridge 246
Des Moines 239
Moscow 215
Beijing 206
Santa Clara 206
Medford 205
Tokyo 203
Frankfurt am Main 177
Nanjing 164
Ho Chi Minh City 153
Los Angeles 135
Princeton 130
New York 122
Boardman 121
Dallas 121
Hanoi 115
Lauterbourg 115
Tulsa 100
Council Bluffs 98
Altamura 89
Dearborn 85
Hefei 83
The Dalles 82
Milan 70
Helsinki 67
Buffalo 64
Lawrence 61
São Paulo 54
Izmir 51
Rome 51
Shenyang 51
Nanchang 46
San Diego 46
Hebei 44
Naples 40
London 39
Abidjan 38
Changsha 38
Venice 37
Chicago 36
Falls Church 34
Brussels 32
Verona 32
Columbus 28
Orem 28
Atlanta 27
Jiaxing 27
Rio de Janeiro 27
Seongnam 27
Ludwigshafen am Rhein 24
Shanghai 24
Bari 23
Toronto 23
Turin 23
Denver 22
Guangzhou 22
Ningbo 22
San Mateo 22
Belo Horizonte 21
Brooklyn 21
Haiphong 21
Jinan 21
Napoli 21
Tianjin 21
Zhengzhou 19
Amsterdam 18
Phoenix 18
Johannesburg 17
Memphis 17
Tashkent 17
Baghdad 16
Nuremberg 16
Auburn Hills 15
Kumar 15
Manchester 15
Montreal 15
Poplar 15
Warsaw 15
Bremen 14
Cardiff 14
Chennai 14
City of London 14
Curitiba 14
Redondo Beach 14
Saint Petersburg 14
Totale 13.082
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Nome #
ANTITUMOR EFFECTS OF CURCUMIN, ALONE OR IN COMBINATION WITH CISPLATIN OR DOXORUBICIN, ON HUMAN HEPATIC CANCER CELLS. ANALYSIS OF THEIR POSSIBLE RELATIONSHIP TO CHANGES IN NF-KB ACTIVATION LEVELS AND IAP GENE EXPRESSION 315
Antitumor effects of curcumin and structurally beta-diketone modified analogs on multidrug resistant cancer cells 295
BRONJ in patients with rheumatoid arthritis: A multicenter case series 276
Farmaci antimicrotubulari 267
Induction of Apoptosis and Chemosensitization by the Histone Deacetylase Inhibitor Trichostatin in Hepatocellular Carcinoma Cells: Molecular Analysis and RKIP Levels 253
"Antitumor effects of the novel NF-kB inhibitor dehydroxymethylepoxyquinomicin (DHMEQ) on human hepatic cancer cells: analysis of synergy with cisplatin and of possible correlation with inhibition of pro-survival genes and IL-6 production”. 249
Analysis of Possible Mechanisms Accounting for Raf-1 Kinase Inhibitor Protein Downregulation in Hepatocellular Carcinoma 249
Epigenetic changes and nuclear factor-κB activation, but not microRNA-224, downregulate Raf-1 kinase inhibitor protein in triple‑negative breast cancer SUM 159 cells 244
Curcumin as a possible lead compound against hormone-independent, multidrug-resistant breast cancer 243
Frequent Alteration of the Yin Yang 1/Raf-1 Kinase Inhibitory Protein Ratio in Hepatocellular Carcinoma 242
Chemotherapy-induced cardiotoxicity: role of the conventional echocardiography and the Tissue Doppler 240
Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells 236
Yin Yang 1 and Raf-1 Kinase Inhibitory Protein Status in Hepatocellular Carcinoma: Future Perspectives 234
Correlation between expression of cyclooxygenase-2 and the presence of inflammatory cells in human primary hepatocellular carcinoma: possible role in tumor promotion and angiogenesis. 231
Farmacovigilanza in oncologia: la nostra esperienza nel "Centro di consulenza ed informazione sugli effetti tossici da farmaci antitumorali e sulle ADR in pazienti neoplastici" della Regione Sicilia 229
The antitumor activities of curcumin and its isoxazole analogue are not affected by multiple gene expression changes in an MDR model of the MCF-7 brest cancer cell line: Analysis of the possible molecular basis. 228
Expression of the IAPs in multidrug resistant tumor cells 227
USE OF HERBAL REMEDIES AMONG CANCER AND TRANSPLANT PATIENTS IN THE TOWN OF PALERMO, SICILY 220
Chemotherapy-induced cardiotoxicity: role of the tissue Doppler in the early diagnosis of left ventricular dysfunction. 219
Sex hormones and risk of liver tumor 215
Effetti della curcumina e di suoi analoghi modificati al frammento beta-dichetone in cellule tumorali multifarmacoresistenti. 214
Alteration of signaling pathways in hepatocellular carcinoma: identification of new pharmacological targets and possible prognosis markers. 214
Interleukin-6 and its soluble receptor in patients with liver cirrhosis and hepatocellular carcinoma. 213
FARMACI INIBITORI DELLE TOPOISOMERASI 213
Pro-oxidant and antitumor effects of curcumin and N-ethylmaleimide in the HA22T/VGH model Overt hepatocellular carcinoma. 212
Uso degli inibitori di pompa protonica in un Policlinico Universitario 208
Expression of WISPs and of their novel alternative variants in human hepatocellular carcinoma cells 207
NF-kB inhibition restores sensitivity to Fas-mediated apoptosis in lymphoma cell lines 206
Cyclooxygenase-2 expression in chronic liver diseases and hepatocellular carcinoma: an immunohistochemical study 206
Multifactorial nature of hepatocellular carcinoma drug resistance: Could plant polyphenols be helpful? 203
Frequent alteration of the Yin Yang 1/Raf-1 Kinase Inhibitory Protein ratio in hepatocellular carcinoma 203
Chemioterapici antibatterici 202
Aspetti etici e controllo di gestione dei farmaci antibiotici antibatterici 200
Novel combination of celecoxib and proteasome inhibitor MG132 provides synergistic antiproliferative and proapoptotic effects in human liver tumor cells 198
Timely recognition of cardiovascular toxicity by anticancer agents: a common objective of the pharmacologist, oncologist and cardiologist. 195
Mechanisms of Raf-1 Kinase Inhibitor Protein Dysregulation in Triple-Negative Breast Cancers and Identification of Possible Novel Therapeutic Approaches for These Tumors 193
Meccanismi di resistenza ai farmaci antitumorali 193
Induction of apoptosis and inhibition of cell growth in human hepatocellular carcinoma cells by COX-2 inhibitors 192
Analysis of UGT1A1*28 and DPYD*2A polymorphisms in Sicilians patients with metastatic colorectal cancer treated with Irinotecan and 5-fluorouracil. 189
Induction of apoptosis by the proteasome inhibitor MG132 in human HCC cells: Possible correlation with specific caspase-dependent cleavage of β-catenin and inhibition of β-catenin-mediated transactivation 187
Fluoroquinolone-induced liver injury: three new cases and a review of the literature. 185
Unusual high dose of tacrolimus in liver transplant patient, a case report. 184
Antitumor effects of the NF-kB inhibitors curcumin and DHMEQ, alone or combined with cisplatin, on hepatic cancer cells. analysis of their relationship to IL-6 production. 183
Antitumor effects of the grape stilbenes resveratrol and piceatannol on multidrug and apoptosis resistant HL60 leukemia cells" 182
The effect of CYP3A5 and ABCB1 single nucleotide polymorphisms on tacrolimus dose requirements in Caucasian liver transplant patients 181
The NF-kB inhibitors curcumin and DHMEQ exert antitumor synergy with cisplatin in hepatic cancer cells. Analysis of relationship to IL-6 production. 178
Commentary. Regulation of drug and immune resistance by YY1 in cancer. 178
Antitumor effects of curcumin in human hepatic cancer cells: Analysis of their relationship to inhibition of NF-kB and pro-survival gene expression. 176
Antitumor effects of curcumin, alone or in combination with cisplatin, on hepatic cancer cells. Analysis of their relationship to IL-6 production 176
Resistance to gemcitabine in a lymphoma cell line resistant to Fas-mediated apoptosis 176
Influence of CYP3A5 and ABCB1 gene polymorphisms and other factors on tacrolimus dosing in Caucasian liver and kidney transplant patients. 176
Findings of osteonecrosis of the jaw under combined bisphosphonate and antiangiogenic therapies: an emergent problem? 174
Pharmacokinetic interaction between tacrolimus and corticosteroids in liver transplant patients 173
Epigenetic agents as an adjunct to active chemotherapy in hematological tumor cell lines 173
Aderenza alle linee guida sulla profilassi antibiotica delle infezioni della ferita chirurgica nel Policlinico Universitario "P. Giaccone" di Palermo 173
Plant polyphenols as possible lead compound against hormone-independent multidrug resistant breast cancer. 169
Pharmacogenetic considerations for optimizing tacrolimus dosing in liver and kidney transplant patients 169
“Antitumor and molecular effects of curcumin and of its isoxazole analogue on multidrug resistant breast cancer cells. New perspectives in tumor theraphy: molecular aspects, 2006”. 168
Farmaci antimicrotubulari. 166
null 164
Lack of nucleophilic addition in the isoxazole and pyrazole diketone modified analogs of curcumin; implications for their antitumor and chemosensitizing activities. 164
From the covalent linkage of drugs to novel inhibitors of ribonucleotide reductase: Synthesis and biological evaluation of valproic esters of 3’-C-methyladenosine 163
Induction of apoptosis by arachidonic acid in human retinoblastoma Y79 cells: involvement of oxidative stress 162
Analysis of pharmacologic approaches able to restore RKIP function in hepatocellular carcinoma 162
NF-kB Is a Potential Molecular Drug Target in Triple-Negative Breast Cancers 162
Induction of apoptosis by the adenosine derivative IB-MECA in parental or multidrug-resistant HL-60 leukemia cells: possibile relationship to the effects on inhibitor of apoptosis protein levels 160
Use of herbal products among cancer and transplanted patients in the town of Palermo,Sicily. 159
Farmaci inibitori delle topoisomerasi 159
Potentiation of the Antitumor Effects of Both Selective Cyclooxygenase-1 and Cyclooxygenase-2 Inhibitors in Human Hepatic Cancer Cells by Inhibition of the MEK/ERK Pathway 159
Le attività antitumorali della curcumina e del suo più potente analogo isossazolico non sono compromesse dal pattern di espressione genica della variante MDR della linea di carcinoma mammario MCF-7 155
Antitumor Effects of Dehydroxymethylepoxyquinomicin, a Novel Nuclear Factor-kappa B Inhibitor, in Human Liver Cancer Cells Are Mediated through a Reactive Oxygen Species-Dependent Mechanism 155
The use of proton pump inhibitors in an Italian hospital: focus on oncologic and critical non-ICU patients 155
Significance of Autologous Interleukin-6 Production in the HA22T/VGH Cell Model of Hepatocellular Carcinoma 155
DISTRIBUTION OF CYP3A5 AND MDR-1 SINGLE NUCLEOTIDE POLYMORPHISMS IN CAUCASIAN LIVER TRANSPLANT PATIENTS 153
Influence of MEK/ERK signaling on apoptosis induced by selective cyclooxygenase-1 and cyclooxygenase-2 inhibitors in human hepatocellular carcinoma cells 153
Expression of IAPs (Inhibitory of Apoptosis Proteins) and of their alternative splice variants in hepatocellular carcinoma tissues and cells 152
Terapia farmacologica in odontoiatria pediatrica 150
Antitumor effects of curcumin and of its combination with cisplatin or doxorubicin on human hepatic cancer cells: possible relationship to NF-kB activation and IAP gene expression. 148
Antitumor effects of novel co-drugs linking histone deacetylase and ribonucleotide reductase inhibitors in hematological tumors 148
Potential Therapeutic Applications of MDA-9/Syntenin-NF-κB-RKIP Loop in Human Liver Carcinoma 148
RUOLO DELL’ECOCOLOR DOPPLER TISSUTALE NELLA VALUTAZIONE DELLA CARDIOTOSSICITÀ DA CHEMIOTERAPICI 147
Prevalence survey of healthcare-associated infections and antimicrobial use at the University Hospital "Paolo Giaccone", Palermo, Italy 147
Circulating IL-6 and sIL-6R in patients with hepatocellular carcinoma 147
Prostaglandin E2 receptors and COX enzymes in human hepatocellular carcinoma: role in the regulation of cell growth 146
Cyclooxygenase-2 expression in chronic liver disease and hepatocellular carcinoma: an immunohistochemical study 145
High dose of trimethoprim-sulfamethoxazole and daptomycin as a therapeutic option for MRSA endocarditis with large vegetation complicated by embolic stroke: a case report and literature review. 143
The antitumor activities of curcumin and of its novel isoxazole analogue MR 39 are not hampered by the multidrug resistant condition of tumor cells expressing both P-glycoprotein and different inhibitory of apoptosis proteins 142
Effetti della curcumina e del suo derivato isossazolico in modelli di neoplasia multifarmacoresistente 141
Possible pharmacological interaction between corticosteroids and a calcineurin inhibitor (tacrolimus) in liver transplant patients. 141
Aspetti etici e Controllo di Gestione dei Farmaci (CoGeF) antibiotici antibatterici. 141
Rash and multiorgan dysfunction following lamotrigine: could genetic be involved? 141
Alteration of the YY1/RKIP ratio is a frequent event in hepatocellular carcinoma 141
ELABORATION OF CURCUMIN INTO DIKETONE MODIFIED ANALOGUES DEVOID OF NUCLEOPHILIC ADDITION CAPABILITY; IMPLICATIONS FOR THEIR ANTITUMOR AND CHEMOSENSITIZING ACTIVITIES 138
NF-κB is a potential pharmacological target in triple negative breast cancers. 136
Anticancer drugs and pharmacovigilance: the Sicilian regional program 132
Effects of curcumin and related analogues on tumor cell lines expressing multiple mechanisms of drug resistance 131
Antitumor effects of curcumin and of its combinations with cisplatin or doxorubicin on human hepatic cancer cells: Possible relationship to NF-kB activation and IAP gene expression 130
Effects of amsacrine (m-AMSA) a new aminoacridine antitumor drug, on the rabbit heart 130
Potential role of the natural multi-targeted agent curcumin in the treatment of oral diseases. 128
Possible mechanisms of Raf-1 Kinase Inhibitor Protein down-regulation in hepatocellular carcinoma 126
Totale 18.359
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Categoria #
all - tutte 69.447
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 69.447
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021153 0 0 0 0 0 0 0 0 0 0 0 153
2021/20221.415 37 342 39 29 79 47 97 60 154 175 73 283
2022/20231.801 187 261 28 180 231 298 187 123 204 13 71 18
2023/2024920 56 163 69 68 60 180 76 61 9 27 22 129
2024/20252.438 46 177 140 247 98 75 195 144 220 257 296 543
2025/20267.979 529 210 436 577 674 1.175 1.062 817 555 1.375 286 283
Totale 22.040