D'ALESSANDRO, Natale
 Distribuzione geografica
Continente #
NA - Nord America 9.689
EU - Europa 6.428
AS - Asia 4.819
SA - Sud America 799
AF - Africa 140
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 2
Totale 21.884
Nazione #
US - Stati Uniti d'America 9.535
IT - Italia 1.666
SG - Singapore 1.663
RU - Federazione Russa 1.361
CN - Cina 1.236
FI - Finlandia 748
UA - Ucraina 733
BR - Brasile 654
HK - Hong Kong 547
DE - Germania 472
VN - Vietnam 444
PL - Polonia 294
IE - Irlanda 283
GB - Regno Unito 261
FR - Francia 249
JP - Giappone 210
SE - Svezia 118
BD - Bangladesh 108
IN - India 108
TR - Turchia 105
KR - Corea 92
CA - Canada 77
IQ - Iraq 58
AR - Argentina 50
NL - Olanda 43
MX - Messico 40
CI - Costa d'Avorio 38
BE - Belgio 37
IR - Iran 36
RO - Romania 31
PK - Pakistan 29
VE - Venezuela 29
ZA - Sudafrica 27
MA - Marocco 24
AT - Austria 23
UZ - Uzbekistan 22
ES - Italia 21
EC - Ecuador 20
MY - Malesia 20
SA - Arabia Saudita 19
ID - Indonesia 18
CH - Svizzera 15
PH - Filippine 15
AL - Albania 14
CZ - Repubblica Ceca 12
EG - Egitto 12
TN - Tunisia 11
AE - Emirati Arabi Uniti 10
AZ - Azerbaigian 10
CL - Cile 10
JM - Giamaica 10
SK - Slovacchia (Repubblica Slovacca) 10
CO - Colombia 9
NP - Nepal 9
PY - Paraguay 9
JO - Giordania 8
LB - Libano 8
LT - Lituania 8
BG - Bulgaria 7
KE - Kenya 7
PE - Perù 7
BH - Bahrain 6
DZ - Algeria 6
EU - Europa 6
CR - Costa Rica 5
GR - Grecia 5
HN - Honduras 5
OM - Oman 5
UY - Uruguay 5
BO - Bolivia 4
GE - Georgia 4
HU - Ungheria 4
IL - Israele 4
KZ - Kazakistan 4
PS - Palestinian Territory 4
TT - Trinidad e Tobago 4
AM - Armenia 3
MM - Myanmar 3
NI - Nicaragua 3
SN - Senegal 3
TH - Thailandia 3
AO - Angola 2
AU - Australia 2
BB - Barbados 2
DK - Danimarca 2
EE - Estonia 2
ET - Etiopia 2
GH - Ghana 2
GY - Guiana 2
HR - Croazia 2
KH - Cambogia 2
LY - Libia 2
MN - Mongolia 2
NG - Nigeria 2
PR - Porto Rico 2
RS - Serbia 2
SV - El Salvador 2
BM - Bermuda 1
BY - Bielorussia 1
DO - Repubblica Dominicana 1
Totale 21.871
Città #
Ashburn 1.103
Singapore 1.088
Fairfield 776
San Jose 653
Chandler 581
Hong Kong 536
Woodbridge 469
Ann Arbor 430
Houston 420
Wilmington 410
Jacksonville 388
Seattle 295
Dublin 280
Palermo 269
Zgierz 265
Cambridge 246
Des Moines 239
Moscow 215
Santa Clara 207
Beijing 206
Medford 205
Tokyo 203
Frankfurt am Main 177
Nanjing 164
Ho Chi Minh City 153
Los Angeles 138
Princeton 130
Dallas 123
New York 123
Boardman 121
Hanoi 116
Lauterbourg 115
Tulsa 100
Council Bluffs 98
Altamura 89
Dearborn 85
Hefei 83
The Dalles 82
Milan 73
Helsinki 67
Buffalo 66
Lawrence 61
Rome 54
São Paulo 54
Izmir 51
Shenyang 51
Nanchang 46
San Diego 46
Hebei 44
London 40
Naples 40
Abidjan 38
Changsha 38
Chicago 37
Venice 37
Falls Church 34
Verona 33
Brussels 32
Atlanta 30
Columbus 29
Orem 28
Jiaxing 27
Rio de Janeiro 27
Seongnam 27
Ludwigshafen am Rhein 24
Shanghai 24
Toronto 24
Bari 23
Brooklyn 23
Turin 23
Denver 22
Guangzhou 22
Ningbo 22
San Mateo 22
Belo Horizonte 21
Haiphong 21
Jinan 21
Napoli 21
Tianjin 21
Phoenix 19
Zhengzhou 19
Amsterdam 18
Johannesburg 17
Memphis 17
Tashkent 17
Baghdad 16
Nuremberg 16
Auburn Hills 15
Kumar 15
Manchester 15
Montreal 15
Poplar 15
Warsaw 15
Bremen 14
Cardiff 14
Chennai 14
City of London 14
Curitiba 14
Redondo Beach 14
Saint Petersburg 14
Totale 13.152
Nome #
ANTITUMOR EFFECTS OF CURCUMIN, ALONE OR IN COMBINATION WITH CISPLATIN OR DOXORUBICIN, ON HUMAN HEPATIC CANCER CELLS. ANALYSIS OF THEIR POSSIBLE RELATIONSHIP TO CHANGES IN NF-KB ACTIVATION LEVELS AND IAP GENE EXPRESSION 316
Antitumor effects of curcumin and structurally beta-diketone modified analogs on multidrug resistant cancer cells 300
BRONJ in patients with rheumatoid arthritis: A multicenter case series 276
Farmaci antimicrotubulari 267
Induction of Apoptosis and Chemosensitization by the Histone Deacetylase Inhibitor Trichostatin in Hepatocellular Carcinoma Cells: Molecular Analysis and RKIP Levels 254
"Antitumor effects of the novel NF-kB inhibitor dehydroxymethylepoxyquinomicin (DHMEQ) on human hepatic cancer cells: analysis of synergy with cisplatin and of possible correlation with inhibition of pro-survival genes and IL-6 production”. 252
Analysis of Possible Mechanisms Accounting for Raf-1 Kinase Inhibitor Protein Downregulation in Hepatocellular Carcinoma 252
Curcumin as a possible lead compound against hormone-independent, multidrug-resistant breast cancer 247
Epigenetic changes and nuclear factor-κB activation, but not microRNA-224, downregulate Raf-1 kinase inhibitor protein in triple‑negative breast cancer SUM 159 cells 245
Frequent Alteration of the Yin Yang 1/Raf-1 Kinase Inhibitory Protein Ratio in Hepatocellular Carcinoma 244
Chemotherapy-induced cardiotoxicity: role of the conventional echocardiography and the Tissue Doppler 240
Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells 237
Yin Yang 1 and Raf-1 Kinase Inhibitory Protein Status in Hepatocellular Carcinoma: Future Perspectives 236
Correlation between expression of cyclooxygenase-2 and the presence of inflammatory cells in human primary hepatocellular carcinoma: possible role in tumor promotion and angiogenesis. 231
The antitumor activities of curcumin and its isoxazole analogue are not affected by multiple gene expression changes in an MDR model of the MCF-7 brest cancer cell line: Analysis of the possible molecular basis. 231
Farmacovigilanza in oncologia: la nostra esperienza nel "Centro di consulenza ed informazione sugli effetti tossici da farmaci antitumorali e sulle ADR in pazienti neoplastici" della Regione Sicilia 231
Expression of the IAPs in multidrug resistant tumor cells 228
USE OF HERBAL REMEDIES AMONG CANCER AND TRANSPLANT PATIENTS IN THE TOWN OF PALERMO, SICILY 223
Chemotherapy-induced cardiotoxicity: role of the tissue Doppler in the early diagnosis of left ventricular dysfunction. 222
FARMACI INIBITORI DELLE TOPOISOMERASI 221
Effetti della curcumina e di suoi analoghi modificati al frammento beta-dichetone in cellule tumorali multifarmacoresistenti. 215
Interleukin-6 and its soluble receptor in patients with liver cirrhosis and hepatocellular carcinoma. 215
Sex hormones and risk of liver tumor 215
Alteration of signaling pathways in hepatocellular carcinoma: identification of new pharmacological targets and possible prognosis markers. 215
Pro-oxidant and antitumor effects of curcumin and N-ethylmaleimide in the HA22T/VGH model Overt hepatocellular carcinoma. 214
Uso degli inibitori di pompa protonica in un Policlinico Universitario 211
Expression of WISPs and of their novel alternative variants in human hepatocellular carcinoma cells 209
NF-kB inhibition restores sensitivity to Fas-mediated apoptosis in lymphoma cell lines 208
Cyclooxygenase-2 expression in chronic liver diseases and hepatocellular carcinoma: an immunohistochemical study 207
Frequent alteration of the Yin Yang 1/Raf-1 Kinase Inhibitory Protein ratio in hepatocellular carcinoma 205
Multifactorial nature of hepatocellular carcinoma drug resistance: Could plant polyphenols be helpful? 204
Chemioterapici antibatterici 202
Aspetti etici e controllo di gestione dei farmaci antibiotici antibatterici 200
Meccanismi di resistenza ai farmaci antitumorali 199
Novel combination of celecoxib and proteasome inhibitor MG132 provides synergistic antiproliferative and proapoptotic effects in human liver tumor cells 198
Timely recognition of cardiovascular toxicity by anticancer agents: a common objective of the pharmacologist, oncologist and cardiologist. 196
Mechanisms of Raf-1 Kinase Inhibitor Protein Dysregulation in Triple-Negative Breast Cancers and Identification of Possible Novel Therapeutic Approaches for These Tumors 195
Induction of apoptosis and inhibition of cell growth in human hepatocellular carcinoma cells by COX-2 inhibitors 193
Analysis of UGT1A1*28 and DPYD*2A polymorphisms in Sicilians patients with metastatic colorectal cancer treated with Irinotecan and 5-fluorouracil. 191
Induction of apoptosis by the proteasome inhibitor MG132 in human HCC cells: Possible correlation with specific caspase-dependent cleavage of β-catenin and inhibition of β-catenin-mediated transactivation 188
Fluoroquinolone-induced liver injury: three new cases and a review of the literature. 188
Antitumor effects of the NF-kB inhibitors curcumin and DHMEQ, alone or combined with cisplatin, on hepatic cancer cells. analysis of their relationship to IL-6 production. 184
Unusual high dose of tacrolimus in liver transplant patient, a case report. 184
Antitumor effects of the grape stilbenes resveratrol and piceatannol on multidrug and apoptosis resistant HL60 leukemia cells" 183
The effect of CYP3A5 and ABCB1 single nucleotide polymorphisms on tacrolimus dose requirements in Caucasian liver transplant patients 183
Commentary. Regulation of drug and immune resistance by YY1 in cancer. 182
The NF-kB inhibitors curcumin and DHMEQ exert antitumor synergy with cisplatin in hepatic cancer cells. Analysis of relationship to IL-6 production. 179
Antitumor effects of curcumin in human hepatic cancer cells: Analysis of their relationship to inhibition of NF-kB and pro-survival gene expression. 178
Antitumor effects of curcumin, alone or in combination with cisplatin, on hepatic cancer cells. Analysis of their relationship to IL-6 production 178
Findings of osteonecrosis of the jaw under combined bisphosphonate and antiangiogenic therapies: an emergent problem? 177
Influence of CYP3A5 and ABCB1 gene polymorphisms and other factors on tacrolimus dosing in Caucasian liver and kidney transplant patients. 177
Resistance to gemcitabine in a lymphoma cell line resistant to Fas-mediated apoptosis 176
Pharmacokinetic interaction between tacrolimus and corticosteroids in liver transplant patients 175
Epigenetic agents as an adjunct to active chemotherapy in hematological tumor cell lines 175
Aderenza alle linee guida sulla profilassi antibiotica delle infezioni della ferita chirurgica nel Policlinico Universitario "P. Giaccone" di Palermo 175
Pharmacogenetic considerations for optimizing tacrolimus dosing in liver and kidney transplant patients 172
Plant polyphenols as possible lead compound against hormone-independent multidrug resistant breast cancer. 171
“Antitumor and molecular effects of curcumin and of its isoxazole analogue on multidrug resistant breast cancer cells. New perspectives in tumor theraphy: molecular aspects, 2006”. 169
Farmaci antimicrotubulari. 167
Analysis of pharmacologic approaches able to restore RKIP function in hepatocellular carcinoma 167
Induction of apoptosis by arachidonic acid in human retinoblastoma Y79 cells: involvement of oxidative stress 165
null 164
Lack of nucleophilic addition in the isoxazole and pyrazole diketone modified analogs of curcumin; implications for their antitumor and chemosensitizing activities. 164
From the covalent linkage of drugs to novel inhibitors of ribonucleotide reductase: Synthesis and biological evaluation of valproic esters of 3’-C-methyladenosine 163
NF-kB Is a Potential Molecular Drug Target in Triple-Negative Breast Cancers 163
Induction of apoptosis by the adenosine derivative IB-MECA in parental or multidrug-resistant HL-60 leukemia cells: possibile relationship to the effects on inhibitor of apoptosis protein levels 162
Farmaci inibitori delle topoisomerasi 160
Potentiation of the Antitumor Effects of Both Selective Cyclooxygenase-1 and Cyclooxygenase-2 Inhibitors in Human Hepatic Cancer Cells by Inhibition of the MEK/ERK Pathway 160
Use of herbal products among cancer and transplanted patients in the town of Palermo,Sicily. 159
The use of proton pump inhibitors in an Italian hospital: focus on oncologic and critical non-ICU patients 158
Le attività antitumorali della curcumina e del suo più potente analogo isossazolico non sono compromesse dal pattern di espressione genica della variante MDR della linea di carcinoma mammario MCF-7 157
Influence of MEK/ERK signaling on apoptosis induced by selective cyclooxygenase-1 and cyclooxygenase-2 inhibitors in human hepatocellular carcinoma cells 157
Significance of Autologous Interleukin-6 Production in the HA22T/VGH Cell Model of Hepatocellular Carcinoma 157
Expression of IAPs (Inhibitory of Apoptosis Proteins) and of their alternative splice variants in hepatocellular carcinoma tissues and cells 155
Antitumor Effects of Dehydroxymethylepoxyquinomicin, a Novel Nuclear Factor-kappa B Inhibitor, in Human Liver Cancer Cells Are Mediated through a Reactive Oxygen Species-Dependent Mechanism 155
DISTRIBUTION OF CYP3A5 AND MDR-1 SINGLE NUCLEOTIDE POLYMORPHISMS IN CAUCASIAN LIVER TRANSPLANT PATIENTS 154
Prevalence survey of healthcare-associated infections and antimicrobial use at the University Hospital "Paolo Giaccone", Palermo, Italy 153
Terapia farmacologica in odontoiatria pediatrica 152
RUOLO DELL’ECOCOLOR DOPPLER TISSUTALE NELLA VALUTAZIONE DELLA CARDIOTOSSICITÀ DA CHEMIOTERAPICI 150
Antitumor effects of novel co-drugs linking histone deacetylase and ribonucleotide reductase inhibitors in hematological tumors 150
Antitumor effects of curcumin and of its combination with cisplatin or doxorubicin on human hepatic cancer cells: possible relationship to NF-kB activation and IAP gene expression. 149
Circulating IL-6 and sIL-6R in patients with hepatocellular carcinoma 149
Potential Therapeutic Applications of MDA-9/Syntenin-NF-κB-RKIP Loop in Human Liver Carcinoma 148
Cyclooxygenase-2 expression in chronic liver disease and hepatocellular carcinoma: an immunohistochemical study 147
Prostaglandin E2 receptors and COX enzymes in human hepatocellular carcinoma: role in the regulation of cell growth 147
High dose of trimethoprim-sulfamethoxazole and daptomycin as a therapeutic option for MRSA endocarditis with large vegetation complicated by embolic stroke: a case report and literature review. 146
Alteration of the YY1/RKIP ratio is a frequent event in hepatocellular carcinoma 144
Effetti della curcumina e del suo derivato isossazolico in modelli di neoplasia multifarmacoresistente 143
The antitumor activities of curcumin and of its novel isoxazole analogue MR 39 are not hampered by the multidrug resistant condition of tumor cells expressing both P-glycoprotein and different inhibitory of apoptosis proteins 143
Possible pharmacological interaction between corticosteroids and a calcineurin inhibitor (tacrolimus) in liver transplant patients. 142
Aspetti etici e Controllo di Gestione dei Farmaci (CoGeF) antibiotici antibatterici. 142
Rash and multiorgan dysfunction following lamotrigine: could genetic be involved? 142
ELABORATION OF CURCUMIN INTO DIKETONE MODIFIED ANALOGUES DEVOID OF NUCLEOPHILIC ADDITION CAPABILITY; IMPLICATIONS FOR THEIR ANTITUMOR AND CHEMOSENSITIZING ACTIVITIES 140
NF-κB is a potential pharmacological target in triple negative breast cancers. 137
Anticancer drugs and pharmacovigilance: the Sicilian regional program 133
Effects of curcumin and related analogues on tumor cell lines expressing multiple mechanisms of drug resistance 132
Antitumor effects of curcumin and of its combinations with cisplatin or doxorubicin on human hepatic cancer cells: Possible relationship to NF-kB activation and IAP gene expression 132
Potential role of the natural multi-targeted agent curcumin in the treatment of oral diseases. 131
Effects of amsacrine (m-AMSA) a new aminoacridine antitumor drug, on the rabbit heart 131
Possible mechanisms of Raf-1 Kinase Inhibitor Protein down-regulation in hepatocellular carcinoma 127
Totale 18.536
Categoria #
all - tutte 70.352
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 70.352


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.415 37 342 39 29 79 47 97 60 154 175 73 283
2022/20231.801 187 261 28 180 231 298 187 123 204 13 71 18
2023/2024920 56 163 69 68 60 180 76 61 9 27 22 129
2024/20252.438 46 177 140 247 98 75 195 144 220 257 296 543
2025/20267.996 529 210 436 577 674 1.175 1.062 817 555 1.375 286 300
2026/2027219 219 0 0 0 0 0 0 0 0 0 0 0
Totale 22.276