Archivio istituzionale della ricerca dell'Università degli Studi di Palermo

PARRINO, Barbara
 Distribuzione geografica
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Continente #
NA - Nord America 6.626
EU - Europa 3.105
AS - Asia 1.372
SA - Sud America 273
AF - Africa 121
OC - Oceania 21
Continente sconosciuto - Info sul continente non disponibili 12
Totale 11.530
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Nazione #
US - Stati Uniti d'America 6.578
IT - Italia 1.334
SG - Singapore 543
CN - Cina 504
DE - Germania 360
FI - Finlandia 351
BR - Brasile 230
SE - Svezia 175
IE - Irlanda 157
GB - Regno Unito 143
UA - Ucraina 134
RU - Federazione Russa 97
FR - Francia 80
CI - Costa d'Avorio 75
IN - India 55
NL - Olanda 46
BE - Belgio 39
RO - Romania 38
GR - Grecia 35
IR - Iran 35
KR - Corea 31
HK - Hong Kong 29
AT - Austria 26
CA - Canada 25
JP - Giappone 25
TR - Turchia 24
CZ - Repubblica Ceca 19
AU - Australia 18
PK - Pakistan 16
MX - Messico 15
CH - Svizzera 14
UZ - Uzbekistan 14
BG - Bulgaria 11
EG - Egitto 11
EU - Europa 11
AR - Argentina 10
ES - Italia 9
IQ - Iraq 9
JO - Giordania 9
MA - Marocco 9
PL - Polonia 9
AE - Emirati Arabi Uniti 7
CL - Cile 7
KE - Kenya 7
LB - Libano 7
RS - Serbia 7
SA - Arabia Saudita 7
VN - Vietnam 7
ZA - Sudafrica 7
MY - Malesia 6
PY - Paraguay 6
BD - Bangladesh 5
CO - Colombia 5
DK - Danimarca 5
DZ - Algeria 5
KZ - Kazakistan 5
PH - Filippine 5
VE - Venezuela 5
BO - Bolivia 4
HR - Croazia 4
ID - Indonesia 4
IL - Israele 4
KG - Kirghizistan 4
TW - Taiwan 4
EC - Ecuador 3
GH - Ghana 3
JM - Giamaica 3
NP - Nepal 3
NZ - Nuova Zelanda 3
AL - Albania 2
AZ - Azerbaigian 2
CU - Cuba 2
LT - Lituania 2
LU - Lussemburgo 2
MD - Moldavia 2
OM - Oman 2
TN - Tunisia 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BH - Bahrain 1
CR - Costa Rica 1
GE - Georgia 1
LA - Repubblica Popolare Democratica del Laos 1
LV - Lettonia 1
MM - Myanmar 1
NO - Norvegia 1
PA - Panama 1
PE - Perù 1
PT - Portogallo 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
SV - El Salvador 1
SY - Repubblica araba siriana 1
TH - Thailandia 1
UG - Uganda 1
Totale 11.530
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Città #
Fairfield 1.031
Ashburn 708
Chandler 480
Woodbridge 462
Palermo 431
Wilmington 413
Seattle 409
Houston 389
Ann Arbor 388
Cambridge 319
Singapore 306
Dublin 155
Medford 151
Nanjing 109
Princeton 104
Altamura 103
Dearborn 80
Abidjan 75
Lawrence 74
San Diego 68
Des Moines 61
Tulsa 61
Ludwigshafen am Rhein 60
Beijing 56
New York 55
Jacksonville 54
Rome 53
Milan 51
Shenyang 50
Boardman 43
Santa Clara 43
Columbus 41
Brussels 35
London 35
Chicago 33
The Dalles 31
Komotiní 30
Tianjin 30
Berlin 29
Nanchang 28
Venice 27
Jinan 26
West Jordan 26
Changsha 24
Hebei 24
Nuremberg 23
Jiaxing 21
Los Angeles 21
Redwood City 21
Council Bluffs 20
Helsinki 20
Timisoara 20
Seongnam 19
Andover 18
San Paolo di Civitate 18
Munich 17
Zhengzhou 17
Central 16
Provo 16
Tokyo 16
Guangzhou 15
Ningbo 15
Saint Petersburg 14
Trapani 14
Frankfurt am Main 13
San Jose 12
São Paulo 12
Brno 11
Falls Church 11
Stockholm 11
Sydney 11
Verona 11
Piscataway 10
Tashkent 10
Tehran 10
Amman 9
Amsterdam 9
Brasília 9
Düsseldorf 9
Hangzhou 9
Hong Kong 9
Lappeenranta 9
Ottawa 9
Toronto 9
Washington 9
Bologna 8
Moscow 8
Mumbai 8
Napoli 8
Pune 8
Vienna 8
Auburn Hills 7
Messina 7
Salerno 7
Sarai Alamgir 7
Buffalo 6
Cagliari 6
Capaci 6
Fremont 6
Kilburn 6
Totale 7.920
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Nome #
1,3,5-Triazines: A promising scaffold for anticancer drugs development 261
[1,2]Oxazolo[5,4-e]isoindoles as promising tubulin polymerization inhibitors 248
2,6-Disubstituted imidazo[2,1-b][1,3,4]thiadiazole derivatives as potent staphylococcal biofilm inhibitors 219
3-[4-(1H-indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, nortopsentin Analogues with antiproliferative activity 215
A Synthetic Derivative of Antimicrobial Peptide Holothuroidin 2 from Mediterranean Sea Cucumber (Holothuria tubulosa) in the Control of Listeria monocytogenes 205
1,2,4-Oxadiazole topsentin analogs as staphylococcal biofilm inhibitors targeting the bacterial transpeptidase sortase A 205
Synthesis and antitumor activity of new thiazole nortopsentin analogs 203
3-(6-Phenylimidazo [2,1-b][1,3,4]thiadiazol-2-yl)-1HIndole derivatives as new anticancer agents in the treatment of pancreatic ductal adenocarcinoma 202
A Facile Synthesis of Deaza-Analogues of the Bisindole Marine Alkaloid Topsentin 187
Synthesis of [1,2]oxazolo[5,4-e]indazoles as antitumour agents 183
Quality, functional and sensory evaluation of pasta fortified with extracts from Opuntia ficus-indica cladodes 173
Polyphenolic Extract from Tarocco (Citrus sinensis L. Osbeck) Clone "Lempso" Exerts Anti-Inflammatory and Antioxidant Effects via NF-kB and Nrf-2 Activation in Murine Macrophages 168
Synthesis of isoindolo[1,4]benzoxazinone and isoindolo[1,5]benzoxazepine: two new ring systems of pharmaceutical interest 166
[1,2]oxazole[5,4-e]isoindoles as promising drugs for anticancer chemotherapy 165
Aza-isoindolo and isoindolo-azaquinoxaline derivatives with antiproliferative activity 165
Synthesis and antiproliferative activity of thiazolyl-bis-pyrrolo[2,3-b]pyridines and indolyl-thiazolyl-pyrrolo[2,3-c]pyridines, nortopsentin analogues 164
CHK1 inhibitor sensitizes resistant colorectal cancer stem cells to nortopsentin 160
An efficient synthesis of pyrrolo[3',2':4,5]thiopyrano[3,2-b]pyridin-2-one: a new ring system of pharmaceutical interest 159
11H‑Pyrido[3′,2′:4,5]pyrrolo[3,2‑c]cinnoline and Pyrido[3′,2′:4,5]pyrrolo[1,2‑c][1,2,3]benzotriazine: Two New Ring Systems with Antitumor Activity 158
Pyrazolo[3,4-h]quinolines promising photosensitizing agents in the treatment of cancer 157
Bacterial Biofilm Inhibition in the Development of Effective Anti-Virulence Strategy 153
New Thiazole Nortopsentin Analogues Inhibit Bacterial Biofilm Formation 148
Synthesis and Antiproliferative Activity of the Ring System[1,2]Oxazolo[4,5-g]indole 147
Convenient synthesis of pyrrolo[3,4-g]indazole 146
Synthesis and antiproliferative mechanism of action of pyrrolo[3′,2′:6,7] cyclohepta[1,2-d]pyrimidin-2-amines as singlet oxygen photosensitizers 142
Nobiletin and Xanthohumol Sensitize Colorectal Cancer Stem Cells to Standard Chemotherapy 141
1,2,4-Amino-triazine derivatives as pyruvate dehydrogenase kinase inhibitors: Synthesis and pharmacological evaluation 140
New 1,2,4-Oxadiazole Nortopsentin Derivatives with Cytotoxic Activity 140
Synthesis and antiproliferative activity of substituted 3[2-(1H-indol-3-yl)-1,3-thiazol-4-yl]-1H-pyrrolo[3,2-b]pyridines, marine alkaloid nortopsentin analogues 140
An overview on the recent developments of 1,2,4-triazine derivatives as anticancer compounds 136
Inhibitors of antibiotic resistance mechanisms: clinical applications and future perspectives 134
Synthesis of pyrazolo[4,3-c][1,2,6]benzothiadiazocine,a new ring system as potential COX inhibitor 133
Water-soluble isoindolo[2,1-a]quinoxalin-6-imines: In vitro antiproliferative activity and molecular mechanism(s) of action 129
Quality characteristics and in vitro digestibility study of barley flour enriched ditalini pasta 128
Synthesis and Antitumor Activity of 3-(2-Phenyl-1,3-thiazol-4-yl)-1H-indoles and 3-(2-Phenyl-1,3-thiazol-4-yl)-1H-7-azaindoles 127
Pharmaceutical Approaches to Target Antibiotic Resistance Mechanisms 127
1,2,4-Oxadiazole Topsentin Analogs with Antiproliferative Activity against Pancreatic Cancer Cells, Targeting GSK3β Kinase 127
Synthesis of the new oligopeptide pyrrole derivative isonetropsin and its one pyrrole unit analogue 124
Synthesis of Triazenoazaindoles: a New Class of Triazenes with Antitumor Activity 123
Synthesis and Antiproliferative Activity of 2,5-bis(3′-Indolyl)pyrroles, Analogues of the Marine Alkaloid Nortopsentin 120
New Tripentone Analogs with Antiproliferative Activity 120
Investigation of Isoindolo[2,1-a] quinoxaline-6-imines as Topoisomerase I Inhibitors with Molecular Modeling Methods 119
Synthesis of substituted isoindolo[2,1-a]quinoxalin-6-yl–amino and 6-imino-5-yl thiourea derivatives 117
‘Interrupted’ diazotization of 3-aminoindoles and 3-aminopyrroles 117
An overview of recent molecular dynamics applications as medicinal chemistry tools for the undruggable site challenge 117
Synthesis of the New Ring System Bispyrido[4',3':4,5]pyrrolo [1,2-a:1',2'-d]pyrazine and Its Deaza Analogue 115
Role of hypoxia in pemetrexed-resistance of mesothelioma mediated by proton-coupled folate transporter, and preclinical activity of new anti-LDH compounds 115
Synthetic small molecules as anti-biofilm agents in the struggle against antibiotic resistance 115
Synthesis of the new ring system pyrrolizino[2,3-b]indol-4(5H)-one 114
Synthesis, antitumor activity and CDK1 inhibiton of new thiazole nortopsentin analogues 113
Synthesis of a new class of pyrrolo[3,4-h]quinazolines with antimitotic activity 112
Synthesis of 5H-pyrido[3,2-b]pyrrolizin-5-one tripentone analogs with antitumor activity 110
Preclinical Activity of New [1,2]Oxazolo[5,4-e]isoindole Derivatives in Diffuse Malignant Peritoneal Mesothelioma 107
Eight-membered heterocycles with two heteroatoms in a 1,5-relationship of interest in medicinal chemistry 105
Derivati di chinossalina, metodi per la loro produzione e loro uso come agenti antitumorali 105
SYNTHESIS AND ANTITUMOR ACTIVITY OF 3-[2-PHENYL-1,3-THIAZOL-4-YL]-1H-7-AZAINDOLES 104
Novel 1H‑Pyrrolo[2,3‑b]pyridine Derivative Nortopsentin Analogues: Synthesis and Antitumor Activity in Peritoneal Mesothelioma Experimental Models 102
Proton-coupled folate transporter as a biomarker of outcome to treatment for pleural mesothelioma 101
Synthesis and photocytotoxic activity of [1,2,3]triazolo[4,5-h][1,6]naphthyridines and [1,3]oxazolo[5,4-h][1,6]naphthyridines 101
Synthesis and antitumor activities of 1,2,3-triazines and their benzo- and heterofused derivatives 98
Multi or Single-Kinase Inhibitors to Counteract Drug Resistance in Cancer: What is New? 96
Imidazo[2,1-b] [1,3,4]thiadiazoles with antiproliferative activity against primary and gemcitabine-resistant pancreatic cancer cells 95
Biological Evaluation of the Antiproliferative and Anti-migratory Activity of a Series of 3-(6-Phenylimidazo[2,1-b][1,3,4]thiadiazol-2-yl)-1H-indole Derivatives against Pancreatic Cancer Cells* 94
Impact of hypoxia on chemoresistance of mesothelioma mediated by the proton-coupled folate transporter, and preclinical activity of new anti-LDH-A compounds 93
Open Sesame? : Biomarker Status of the Human Equilibrative Nucleoside Transporter-1 and Molecular Mechanisms Influencing its Expression and Activity in the Uptake and Cytotoxicity of Gemcitabine in Pancreatic Cancer 90
2-substituted-[1,3]thiazolo[4,5-e]isoindoles as kinases inhibiting compounds 89
A computational study to explore the molecular mechanisms behind the antiproliferative activity of Nortopsentin derivatives 88
Pyrrolo[3′,2′:6,7]cyclohepta[1,2-b]pyridines with potent photo-antiproliferative activity 87
Eight-Membered Rings With Two Heteroatoms 1,5 86
New Imidazo[2,1-b][1,3,4]Thiadiazole Derivatives Inhibit FAK Phosphorylation and Potentiate the Antiproliferative Effects of Gemcitabine Through Modulation of the Human Equilibrative Nucleoside Transporter-1 in Peritoneal Mesothelioma 84
A New Oxadiazole-Based Topsentin Derivative Modulates Cyclin-Dependent Kinase 1 Expression and Exerts Cytotoxic Effects on Pancreatic Cancer Cells 84
Antitumor activity of 2,5-bis-(3’-indolyl)-pyrroles, deaza-analogues of Nortopsentins 78
Dynamic-shared pharmacophore approach as tool to design new allosteric PRC2 inhibitors, targeting EED binding pocket 78
Eight-membered heterocycles with two heteroatoms in a 1,3-relationship of interest in medicinal chemistry 78
Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification 77
7-Azaindole-fused heterocycles with antitumor activity 76
Biological evaluation of new 1,2,4-oxadiazole topsentin analogs as anticancer agents 76
New Topsentin analogs as inhibitors of biofilm formation 76
Therapeutic strategies to counteract antibiotic resistance in MRSA biofilm-associated infections 74
Thiazole Analogues of the Marine Alkaloid Nortopsentin as Inhibitors of Bacterial Biofilm Formation 73
1,3,4-Oxadiazole and 1,3,4-Thiadiazole Nortopsentin Derivatives against Pancreatic Ductal Adenocarcinoma: Synthesis, Cytotoxic Activity, and Inhibition of CDK1 72
Itraconazole inhibits nuclear delivery of extracellular vesicle cargo by disrupting the entry of late endosomes into the nucleoplasmic reticulum 69
Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic Resistance 68
SYNTHESIS OF TETRACYCLIC SYSTEMS WITH POTENT ANTITUMOR ACTIVITY 66
Synthesis and biological evaluation of pyrrolo[3’,2’:6,7]cyclohepta[1,2-d]pyrimidin-2-amines 66
3-[2-(1H-Indol-3-yl)-1,3-thiazol-4-yl)-1H-4-azaindole a new series of kinase inhibitors 65
In vitro digestion of beta glucan enriched pasta: polysaccharide molecular characterization and antioxidant activity of bioaccessible fraction. 63
Pharmacogenetics of treatments for pancreatic cancer 62
A Combination of Polymethoxyflavones from Citrus sinensis and Prenylflavonoids from Humulus lupulus Counteracts IL-1β-Induced Differentiated Caco-2 Cells Dysfunction via a Modulation of NF-κB/Nrf2 Activation 61
SYNTHESYS AND ANTITUMOR ACTIVITY OF ISOINDOLO [2,1-A]QUINOXALIN-6-IMINES AND THEIR AZA-ANALOGUES 61
Nortopsentins as Leads from Marine Organisms for Anticancer and Anti-Inflammatory Agent Development 60
Condensed azaindole with antitumor activity 60
Eight-Membered Rings With Two Heteroatoms 1,2 58
SF3B1 modulators affect key genes in metastasis and drug influx: a new approach to fight pancreatic cancer chemoresistance 57
Eight-membered heterocycles with two heteroatoms in a 1,2-relationship of interest in medicinal chemistry 57
Immunomodulatory activity of Humulus lupulus bitter acids fraction: Enhancement of natural killer cells function by NKp44 activating receptor stimulation 56
Synthesis of condensed quinoxalines with potent antitumor activity 54
Synthesis and antitumor activity of new tetracyclic systems containing the pyrrole ring. 53
In vitro digestion of beta glucan enriched pasta and antioxidant potential of digesta 53
Quality characteristic and in vitro digestibility study of barley flour enriched ditalini pasta 53
Totale 11.561
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Categoria #
all - tutte 53.193
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 53.193
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020416 0 0 0 0 0 0 0 0 0 108 197 111
2020/20211.666 68 100 71 162 194 117 106 192 150 224 147 135
2021/20221.739 142 321 68 56 36 64 76 116 259 219 96 286
2022/20231.743 199 311 41 119 168 239 72 155 221 51 73 94
2023/20241.129 49 116 64 61 85 163 124 113 35 81 43 195
2024/20251.850 133 96 190 196 90 119 210 281 246 289 0 0
Totale 12.336