Archivio istituzionale della ricerca dell'Università degli Studi di Palermo

PARRINO, Barbara
 Distribuzione geografica
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Continente #
NA - Nord America 10.995
EU - Europa 5.294
AS - Asia 4.199
SA - Sud America 739
AF - Africa 212
OC - Oceania 21
Continente sconosciuto - Info sul continente non disponibili 12
Totale 21.472
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Nazione #
US - Stati Uniti d'America 10.822
SG - Singapore 1.599
IT - Italia 1.446
RU - Federazione Russa 1.333
CN - Cina 1.040
BR - Brasile 572
DE - Germania 490
HK - Hong Kong 411
FI - Finlandia 405
VN - Vietnam 383
PL - Polonia 270
FR - Francia 248
GB - Regno Unito 228
SE - Svezia 189
IE - Irlanda 167
UA - Ucraina 167
JP - Giappone 146
IN - India 122
KR - Corea 85
CI - Costa d'Avorio 75
NL - Olanda 69
CA - Canada 66
MX - Messico 66
BD - Bangladesh 64
AR - Argentina 56
IQ - Iraq 42
IR - Iran 41
AT - Austria 40
BE - Belgio 40
RO - Romania 40
GR - Grecia 37
TR - Turchia 33
PK - Pakistan 29
UZ - Uzbekistan 29
ES - Italia 25
ID - Indonesia 25
CL - Cile 24
EG - Egitto 22
CZ - Repubblica Ceca 21
ZA - Sudafrica 21
EC - Ecuador 20
SA - Arabia Saudita 19
AU - Australia 18
KE - Kenya 18
VE - Venezuela 18
MA - Marocco 17
MY - Malesia 17
CO - Colombia 16
JO - Giordania 16
CH - Svizzera 14
NG - Nigeria 14
BG - Bulgaria 13
DZ - Algeria 13
PH - Filippine 13
RS - Serbia 13
NP - Nepal 12
PY - Paraguay 12
EU - Europa 11
AE - Emirati Arabi Uniti 10
TN - Tunisia 10
BO - Bolivia 8
IL - Israele 8
LB - Libano 8
LT - Lituania 8
TW - Taiwan 8
KZ - Kazakistan 7
UY - Uruguay 7
JM - Giamaica 6
KG - Kirghizistan 6
PA - Panama 6
SN - Senegal 6
CR - Costa Rica 5
DK - Danimarca 5
OM - Oman 5
PE - Perù 5
TH - Thailandia 5
AL - Albania 4
BY - Bielorussia 4
ET - Etiopia 4
GT - Guatemala 4
HR - Croazia 4
AZ - Azerbaigian 3
BH - Bahrain 3
GA - Gabon 3
GH - Ghana 3
HN - Honduras 3
MD - Moldavia 3
ME - Montenegro 3
NZ - Nuova Zelanda 3
TT - Trinidad e Tobago 3
CU - Cuba 2
DO - Repubblica Dominicana 2
GE - Georgia 2
LU - Lussemburgo 2
NI - Nicaragua 2
NO - Norvegia 2
PR - Porto Rico 2
PS - Palestinian Territory 2
SV - El Salvador 2
SY - Repubblica araba siriana 2
Totale 21.452
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Città #
Dallas 2.238
Ashburn 1.116
Fairfield 1.031
Singapore 950
Chandler 481
Woodbridge 462
San Jose 440
Palermo 439
Wilmington 414
Seattle 411
Houston 400
Ann Arbor 388
Hong Kong 381
Cambridge 319
Zgierz 235
Moscow 188
Beijing 180
Council Bluffs 173
Dublin 164
Medford 151
Tokyo 135
Ho Chi Minh City 131
Los Angeles 124
Frankfurt am Main 113
New York 112
Nanjing 110
Lauterbourg 104
Princeton 104
Altamura 103
Santa Clara 99
Dearborn 80
Hanoi 78
Des Moines 77
Hefei 77
Abidjan 75
Lawrence 74
Buffalo 71
Chicago 71
San Diego 68
Rome 64
The Dalles 63
Tulsa 62
Helsinki 61
Ludwigshafen am Rhein 60
Milan 59
Jacksonville 57
Shenyang 50
Boardman 48
London 48
São Paulo 47
Columbus 46
Tianjin 37
Brussels 36
Komotiní 30
Nuremberg 30
Berlin 29
Jinan 29
Nanchang 28
Changsha 27
Redondo Beach 27
Venice 27
West Jordan 26
Hebei 24
Kyiv 24
Tashkent 24
Guangzhou 22
Munich 22
Paris 22
Warsaw 22
Baghdad 21
Jiaxing 21
Redwood City 21
Amsterdam 20
Chennai 20
Orem 20
Stockholm 20
Timisoara 20
Zhengzhou 20
Da Nang 19
Denver 19
Seongnam 19
Toronto 19
Andover 18
Brooklyn 18
Phoenix 18
San Paolo di Civitate 18
Mumbai 17
Central 16
Ningbo 16
Provo 16
Rio de Janeiro 16
Vienna 16
Belfast 15
Montreal 15
Amman 14
Brasília 14
Lappeenranta 14
Mexico City 14
Saint Petersburg 14
Tehran 14
Totale 14.060
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Nome #
1,2,4-Oxadiazole topsentin analogs as staphylococcal biofilm inhibitors targeting the bacterial transpeptidase sortase A 1.073
1,2,4-Amino-triazine derivatives as pyruvate dehydrogenase kinase inhibitors: Synthesis and pharmacological evaluation 975
1,2,4-Oxadiazole Topsentin Analogs with Antiproliferative Activity against Pancreatic Cancer Cells, Targeting GSK3β Kinase 954
1,3,5-Triazines: A promising scaffold for anticancer drugs development 377
3-(6-Phenylimidazo [2,1-b][1,3,4]thiadiazol-2-yl)-1HIndole derivatives as new anticancer agents in the treatment of pancreatic ductal adenocarcinoma 338
[1,2]Oxazolo[5,4-e]isoindoles as promising tubulin polymerization inhibitors 330
3-[4-(1H-indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, nortopsentin Analogues with antiproliferative activity 315
2,6-Disubstituted imidazo[2,1-b][1,3,4]thiadiazole derivatives as potent staphylococcal biofilm inhibitors 300
A Synthetic Derivative of Antimicrobial Peptide Holothuroidin 2 from Mediterranean Sea Cucumber (Holothuria tubulosa) in the Control of Listeria monocytogenes 293
A Facile Synthesis of Deaza-Analogues of the Bisindole Marine Alkaloid Topsentin 273
Quality, functional and sensory evaluation of pasta fortified with extracts from Opuntia ficus-indica cladodes 264
CHK1 inhibitor sensitizes resistant colorectal cancer stem cells to nortopsentin 259
Synthesis and antitumor activity of new thiazole nortopsentin analogs 257
An efficient synthesis of pyrrolo[3',2':4,5]thiopyrano[3,2-b]pyridin-2-one: a new ring system of pharmaceutical interest 246
Aza-isoindolo and isoindolo-azaquinoxaline derivatives with antiproliferative activity 246
Nobiletin and Xanthohumol Sensitize Colorectal Cancer Stem Cells to Standard Chemotherapy 244
11H‑Pyrido[3′,2′:4,5]pyrrolo[3,2‑c]cinnoline and Pyrido[3′,2′:4,5]pyrrolo[1,2‑c][1,2,3]benzotriazine: Two New Ring Systems with Antitumor Activity 243
[1,2]oxazole[5,4-e]isoindoles as promising drugs for anticancer chemotherapy 240
Synthesis of [1,2]oxazolo[5,4-e]indazoles as antitumour agents 237
Synthesis of isoindolo[1,4]benzoxazinone and isoindolo[1,5]benzoxazepine: two new ring systems of pharmaceutical interest 235
Synthesis and antiproliferative activity of thiazolyl-bis-pyrrolo[2,3-b]pyridines and indolyl-thiazolyl-pyrrolo[2,3-c]pyridines, nortopsentin analogues 215
Pyrazolo[3,4-h]quinolines promising photosensitizing agents in the treatment of cancer 214
An overview of recent molecular dynamics applications as medicinal chemistry tools for the undruggable site challenge 211
An overview on the recent developments of 1,2,4-triazine derivatives as anticancer compounds 209
Synthesis and antiproliferative mechanism of action of pyrrolo[3′,2′:6,7] cyclohepta[1,2-d]pyrimidin-2-amines as singlet oxygen photosensitizers 208
Polyphenolic Extract from Tarocco (Citrus sinensis L. Osbeck) Clone "Lempso" Exerts Anti-Inflammatory and Antioxidant Effects via NF-kB and Nrf-2 Activation in Murine Macrophages 205
Water-soluble isoindolo[2,1-a]quinoxalin-6-imines: In vitro antiproliferative activity and molecular mechanism(s) of action 202
Synthesis of pyrazolo[4,3-c][1,2,6]benzothiadiazocine,a new ring system as potential COX inhibitor 200
Role of hypoxia in pemetrexed-resistance of mesothelioma mediated by proton-coupled folate transporter, and preclinical activity of new anti-LDH compounds 199
2-substituted-[1,3]thiazolo[4,5-e]isoindoles as kinases inhibiting compounds 197
Convenient synthesis of pyrrolo[3,4-g]indazole 195
Inhibitors of antibiotic resistance mechanisms: clinical applications and future perspectives 192
Synthesis and antiproliferative activity of substituted 3[2-(1H-indol-3-yl)-1,3-thiazol-4-yl]-1H-pyrrolo[3,2-b]pyridines, marine alkaloid nortopsentin analogues 192
New Thiazole Nortopsentin Analogues Inhibit Bacterial Biofilm Formation 188
Synthesis and Antiproliferative Activity of the Ring System[1,2]Oxazolo[4,5-g]indole 186
Bacterial Biofilm Inhibition in the Development of Effective Anti-Virulence Strategy 185
‘Interrupted’ diazotization of 3-aminoindoles and 3-aminopyrroles 182
A Combination of Polymethoxyflavones from Citrus sinensis and Prenylflavonoids from Humulus lupulus Counteracts IL-1β-Induced Differentiated Caco-2 Cells Dysfunction via a Modulation of NF-κB/Nrf2 Activation 180
New 1,2,4-Oxadiazole Nortopsentin Derivatives with Cytotoxic Activity 180
Synthesis and Antitumor Activity of 3-(2-Phenyl-1,3-thiazol-4-yl)-1H-indoles and 3-(2-Phenyl-1,3-thiazol-4-yl)-1H-7-azaindoles 178
Biological Evaluation of the Antiproliferative and Anti-migratory Activity of a Series of 3-(6-Phenylimidazo[2,1-b][1,3,4]thiadiazol-2-yl)-1H-indole Derivatives against Pancreatic Cancer Cells* 178
Pharmaceutical Approaches to Target Antibiotic Resistance Mechanisms 178
Open Sesame? : Biomarker Status of the Human Equilibrative Nucleoside Transporter-1 and Molecular Mechanisms Influencing its Expression and Activity in the Uptake and Cytotoxicity of Gemcitabine in Pancreatic Cancer 176
Synthesis of substituted isoindolo[2,1-a]quinoxalin-6-yl–amino and 6-imino-5-yl thiourea derivatives 171
Eight-membered heterocycles with two heteroatoms in a 1,5-relationship of interest in medicinal chemistry 171
A New Oxadiazole-Based Topsentin Derivative Modulates Cyclin-Dependent Kinase 1 Expression and Exerts Cytotoxic Effects on Pancreatic Cancer Cells 171
Eight-Membered Rings With Two Heteroatoms 1,5 169
New Tripentone Analogs with Antiproliferative Activity 169
Synthesis of Triazenoazaindoles: a New Class of Triazenes with Antitumor Activity 169
1,3,4-Oxadiazole and 1,3,4-Thiadiazole Nortopsentin Derivatives against Pancreatic Ductal Adenocarcinoma: Synthesis, Cytotoxic Activity, and Inhibition of CDK1 168
7-Azaindole-fused heterocycles with antitumor activity 164
SYNTHESIS AND ANTITUMOR ACTIVITY OF 3-[2-PHENYL-1,3-THIAZOL-4-YL]-1H-7-AZAINDOLES 162
Pyrrolo[3′,2′:6,7]cyclohepta[1,2-b]pyridines with potent photo-antiproliferative activity 162
A computational study to explore the molecular mechanisms behind the antiproliferative activity of Nortopsentin derivatives 162
Multi or Single-Kinase Inhibitors to Counteract Drug Resistance in Cancer: What is New? 160
Synthesis and Antiproliferative Activity of 2,5-bis(3′-Indolyl)pyrroles, Analogues of the Marine Alkaloid Nortopsentin 160
Quality characteristics and in vitro digestibility study of barley flour enriched ditalini pasta 160
New Imidazo[2,1-b][1,3,4]Thiadiazole Derivatives Inhibit FAK Phosphorylation and Potentiate the Antiproliferative Effects of Gemcitabine Through Modulation of the Human Equilibrative Nucleoside Transporter-1 in Peritoneal Mesothelioma 160
Synthesis of the new ring system pyrrolizino[2,3-b]indol-4(5H)-one 159
Investigation of Isoindolo[2,1-a] quinoxaline-6-imines as Topoisomerase I Inhibitors with Molecular Modeling Methods 158
Synthesis of the new oligopeptide pyrrole derivative isonetropsin and its one pyrrole unit analogue 157
Synthesis of a new class of pyrrolo[3,4-h]quinazolines with antimitotic activity 157
Synthesis of 5H-pyrido[3,2-b]pyrrolizin-5-one tripentone analogs with antitumor activity 156
Synthesis of the New Ring System Bispyrido[4',3':4,5]pyrrolo [1,2-a:1',2'-d]pyrazine and Its Deaza Analogue 154
Preclinical Activity of New [1,2]Oxazolo[5,4-e]isoindole Derivatives in Diffuse Malignant Peritoneal Mesothelioma 154
Proton-coupled folate transporter as a biomarker of outcome to treatment for pleural mesothelioma 153
Synthetic small molecules as anti-biofilm agents in the struggle against antibiotic resistance 153
Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification 150
Synthesis and biological evaluation of pyrrolo[3’,2’:6,7]cyclohepta[1,2-d]pyrimidin-2-amines 149
Synthesis, antitumor activity and CDK1 inhibiton of new thiazole nortopsentin analogues 148
Therapeutic strategies to counteract antibiotic resistance in MRSA biofilm-associated infections 148
Impact of hypoxia on chemoresistance of mesothelioma mediated by the proton-coupled folate transporter, and preclinical activity of new anti-LDH-A compounds 148
Eight-membered heterocycles with two heteroatoms in a 1,3-relationship of interest in medicinal chemistry 146
Novel 1H‑Pyrrolo[2,3‑b]pyridine Derivative Nortopsentin Analogues: Synthesis and Antitumor Activity in Peritoneal Mesothelioma Experimental Models 144
Biological evaluation of new 1,2,4-oxadiazole topsentin analogs as anticancer agents 143
New Marine-Inspired Oxadiazole Derivatives for Use Against Pancreatic Ductal Adenocarcinoma 142
Dynamic-shared pharmacophore approach as tool to design new allosteric PRC2 inhibitors, targeting EED binding pocket 142
Itraconazole inhibits nuclear delivery of extracellular vesicle cargo by disrupting the entry of late endosomes into the nucleoplasmic reticulum 141
Eight-membered heterocycles with two heteroatoms in a 1,2-relationship of interest in medicinal chemistry 141
Imidazo[2,1-b] [1,3,4]thiadiazoles with antiproliferative activity against primary and gemcitabine-resistant pancreatic cancer cells 140
Derivati di chinossalina, metodi per la loro produzione e loro uso come agenti antitumorali 140
3-[2-(1H-Indol-3-yl)-1,3-thiazol-4-yl)-1H-4-azaindole a new series of kinase inhibitors 137
Nortopsentins as Leads from Marine Organisms for Anticancer and Anti-Inflammatory Agent Development 136
Synthesis and photocytotoxic activity of [1,2,3]triazolo[4,5-h][1,6]naphthyridines and [1,3]oxazolo[5,4-h][1,6]naphthyridines 134
Synthesis and antitumor activities of 1,2,3-triazines and their benzo- and heterofused derivatives 133
In vitro digestion of beta glucan enriched pasta: polysaccharide molecular characterization and antioxidant activity of bioaccessible fraction. 128
Exploring the therapeutic potential of focal adhesion kinase inhibition in overcoming chemoresistance in pancreatic ductal adenocarcinoma 124
Eight-Membered Rings With Two Heteroatoms 1,2 123
Antitumor activity of 2,5-bis-(3’-indolyl)-pyrroles, deaza-analogues of Nortopsentins 119
New Topsentin analogs as inhibitors of biofilm formation 117
SF3B1 modulators affect key genes in metastasis and drug influx: a new approach to fight pancreatic cancer chemoresistance 117
Eight-Membered Rings With Two Heteroatoms 1,3 114
Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic Resistance 114
Thiazole Analogues of the Marine Alkaloid Nortopsentin as Inhibitors of Bacterial Biofilm Formation 112
SYNTHESIS OF TETRACYCLIC SYSTEMS WITH POTENT ANTITUMOR ACTIVITY 111
Pharmacogenetics of treatments for pancreatic cancer 111
SYNTHESYS AND ANTITUMOR ACTIVITY OF ISOINDOLO [2,1-A]QUINOXALIN-6-IMINES AND THEIR AZA-ANALOGUES 104
SYNTHESIS AND ANTITUMOR ACTIVITY IN PERITONEAL MESOTHELIOMA EXPERIMENTAL MODELS OF 1H-PIRROLO[2,3-b]PYRIDINE DERIVATIVES 103
Discovery of the 3-Amino-1,2,4-triazine-Based Library as Selective PDK1 Inhibitors with Therapeutic Potential in Highly Aggressive Pancreatic Ductal Adenocarcinoma 102
Immunomodulatory activity of Humulus lupulus bitter acids fraction: Enhancement of natural killer cells function by NKp44 activating receptor stimulation 102
Totale 20.291
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Categoria #
all - tutte 74.234
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 74.234
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021282 0 0 0 0 0 0 0 0 0 0 147 135
2021/20221.739 142 321 68 56 36 64 76 116 259 219 96 286
2022/20231.743 199 311 41 119 168 239 72 155 221 51 73 94
2023/20241.129 49 116 64 61 85 163 124 113 35 81 43 195
2024/20252.665 133 96 190 196 90 119 210 281 246 297 297 510
2025/20269.142 543 987 1.868 628 697 913 1.106 778 656 678 288 0
Totale 22.293