Archivio istituzionale della ricerca dell'Università degli Studi di Palermo
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EnglishThis review covering literature reports from the beginning of this century to 2016 describes the synthetic pathways, the antitumor activity, the structure-activity relationship and, whenever reported, the possible mechanism of action of 1,3,5-triazine derivatives as well as of their hetero-fused compounds. Many 1,3,5-triazine derivatives, both uncondensed and hetero-fused, have shown remarkable antitumor activities and some of them reached clinical development.
Cascioferro, S., Parrino, B., Spanò, V., Carbone, A., Montalbano, A., Barraja, P., et al. (2017). 1,3,5-Triazines: A promising scaffold for anticancer drugs development. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 142, 523-549.
| Data di pubblicazione: | 2017 |
| Titolo: | 1,3,5-Triazines: A promising scaffold for anticancer drugs development |
| Autori: | |
| Citazione: | Cascioferro, S., Parrino, B., Spanò, V., Carbone, A., Montalbano, A., Barraja, P., et al. (2017). 1,3,5-Triazines: A promising scaffold for anticancer drugs development. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 142, 523-549. |
| Rivista: | |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/j.ejmech.2017.09.035 |
| Abstract: | This review covering literature reports from the beginning of this century to 2016 describes the synthetic pathways, the antitumor activity, the structure-activity relationship and, whenever reported, the possible mechanism of action of 1,3,5-triazine derivatives as well as of their hetero-fused compounds. Many 1,3,5-triazine derivatives, both uncondensed and hetero-fused, have shown remarkable antitumor activities and some of them reached clinical development. |
| URL: | http://www.journals.elsevier.com/european-journal-of-medicinal-chemistry/ |
| Appare nelle tipologie: | 1.01 Articolo in rivista |
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