Derivatives of the new ring system 1,4-dihydropyrazolo[4,3-c][1,2,6] benzothiadiazocin-11(10H)one 5,5-dioxide were synthesized in five or six steps in 57-66% overall yields and tested as COX inhibitors.
Migliara, O., Spanò, V., Parrino, B., Ciancimino, C., Diana, P. (2012). Synthesis of pyrazolo[4,3-c][1,2,6]benzothiadiazocine,a new ring system as potential COX inhibitor. ARKIVOC, II, 41-49.
Synthesis of pyrazolo[4,3-c][1,2,6]benzothiadiazocine,a new ring system as potential COX inhibitor
SPANO', Virginia;PARRINO, Barbara;CIANCIMINO, Cristina;DIANA, Patrizia
2012-01-01
Abstract
Derivatives of the new ring system 1,4-dihydropyrazolo[4,3-c][1,2,6] benzothiadiazocin-11(10H)one 5,5-dioxide were synthesized in five or six steps in 57-66% overall yields and tested as COX inhibitors.
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