SPANO', Virginia
 Distribuzione geografica
Continente #
NA - Nord America 7.373
EU - Europa 4.375
AS - Asia 3.365
SA - Sud America 628
AF - Africa 137
Continente sconosciuto - Info sul continente non disponibili 15
OC - Oceania 11
Totale 15.904
Nazione #
US - Stati Uniti d'America 7.238
IT - Italia 1.336
SG - Singapore 1.193
RU - Federazione Russa 1.015
CN - Cina 836
BR - Brasile 494
FI - Finlandia 401
DE - Germania 358
HK - Hong Kong 336
VN - Vietnam 330
PL - Polonia 210
IE - Irlanda 185
GB - Regno Unito 184
FR - Francia 157
UA - Ucraina 148
JP - Giappone 140
SE - Svezia 134
KR - Corea 106
BD - Bangladesh 84
IN - India 69
CA - Canada 65
NL - Olanda 62
IQ - Iraq 52
AR - Argentina 46
MX - Messico 36
BE - Belgio 33
CI - Costa d'Avorio 32
AT - Austria 31
RO - Romania 26
TR - Turchia 26
UZ - Uzbekistan 24
ID - Indonesia 22
TW - Taiwan 22
MY - Malesia 21
EG - Egitto 20
EC - Ecuador 18
CH - Svizzera 17
IR - Iran 17
ES - Italia 16
ZA - Sudafrica 16
VE - Venezuela 15
CL - Cile 14
CO - Colombia 14
CZ - Repubblica Ceca 14
EU - Europa 13
NG - Nigeria 13
PK - Pakistan 13
PY - Paraguay 13
DZ - Algeria 12
KE - Kenya 12
MA - Marocco 11
SA - Arabia Saudita 11
NP - Nepal 9
TN - Tunisia 9
BG - Bulgaria 8
GR - Grecia 8
PH - Filippine 8
AU - Australia 7
JM - Giamaica 7
PA - Panama 7
TH - Thailandia 7
UY - Uruguay 7
KZ - Kazakistan 6
BO - Bolivia 5
HU - Ungheria 5
LB - Libano 5
AL - Albania 4
IL - Israele 4
NZ - Nuova Zelanda 4
RS - Serbia 4
AE - Emirati Arabi Uniti 3
AZ - Azerbaigian 3
BY - Bielorussia 3
CR - Costa Rica 3
DK - Danimarca 3
DO - Repubblica Dominicana 3
ET - Etiopia 3
JO - Giordania 3
ME - Montenegro 3
OM - Oman 3
SV - El Salvador 3
TT - Trinidad e Tobago 3
AO - Angola 2
BA - Bosnia-Erzegovina 2
BH - Bahrain 2
BS - Bahamas 2
CG - Congo 2
GH - Ghana 2
GT - Guatemala 2
NO - Norvegia 2
PE - Perù 2
PS - Palestinian Territory 2
SY - Repubblica araba siriana 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BN - Brunei Darussalam 1
CW - ???statistics.table.value.countryCode.CW??? 1
EE - Estonia 1
GA - Gabon 1
GD - Grenada 1
GE - Georgia 1
Totale 15.890
Città #
Ashburn 887
Fairfield 863
Singapore 725
Palermo 442
San Jose 435
Woodbridge 401
Houston 395
Chandler 382
Wilmington 361
Ann Arbor 339
Seattle 339
Hong Kong 292
Cambridge 264
Zgierz 189
Dublin 179
Beijing 163
Council Bluffs 153
Moscow 152
Medford 126
Tokyo 126
Ho Chi Minh City 111
Nanjing 92
Dallas 90
Hanoi 90
Los Angeles 88
Princeton 84
Santa Clara 83
Lauterbourg 77
New York 74
Dearborn 71
Jacksonville 68
Altamura 67
Des Moines 66
Frankfurt am Main 65
Helsinki 63
The Dalles 62
Tulsa 62
Chicago 55
San Diego 55
Boardman 54
Lawrence 54
Milan 49
Hefei 44
Shenyang 41
Buffalo 39
Seongnam 38
Ludwigshafen am Rhein 36
Rome 34
São Paulo 34
Abidjan 32
London 32
Brussels 29
Nanchang 27
Hebei 26
Jinan 25
Nuremberg 25
Columbus 22
Berlin 21
Tianjin 21
Baghdad 20
Orem 20
San Paolo di Civitate 20
Tashkent 20
Napoli 19
Guangzhou 18
Rio de Janeiro 18
Zhengzhou 18
Changsha 17
Redondo Beach 17
Toronto 17
Vienna 17
Naples 16
Andover 15
Montreal 15
Paris 15
Redwood City 15
Central 14
Ningbo 14
Saint Petersburg 14
Stockholm 14
Timisoara 14
Amsterdam 12
Denver 12
Erbil 12
Hangzhou 12
Kuala Lumpur 12
Munich 12
Piscataway 12
Salt Lake City 12
Warsaw 12
Abuja 11
Atlanta 11
Belfast 11
Belo Horizonte 11
Cairo 11
Da Nang 11
Haiphong 11
Ottawa 11
Venice 11
Washington 11
Totale 9.904
Nome #
1,3,5-Triazines: A promising scaffold for anticancer drugs development 380
[1,2]Oxazolo[5,4-e]isoindoles as promising tubulin polymerization inhibitors 332
3-[4-(1H-indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, nortopsentin Analogues with antiproliferative activity 320
Targeting Multiple Myeloma with natural polyphenols 279
A Facile Synthesis of Deaza-Analogues of the Bisindole Marine Alkaloid Topsentin 277
Current development of CFTR potentiators in the last decade 268
Quality, functional and sensory evaluation of pasta fortified with extracts from Opuntia ficus-indica cladodes 265
Synthesis and antitumor activity of new thiazole nortopsentin analogs 261
Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds 257
11H‑Pyrido[3′,2′:4,5]pyrrolo[3,2‑c]cinnoline and Pyrido[3′,2′:4,5]pyrrolo[1,2‑c][1,2,3]benzotriazine: Two New Ring Systems with Antitumor Activity 254
An efficient synthesis of pyrrolo[3',2':4,5]thiopyrano[3,2-b]pyridin-2-one: a new ring system of pharmaceutical interest 251
Aza-isoindolo and isoindolo-azaquinoxaline derivatives with antiproliferative activity 247
[1,2]oxazole[5,4-e]isoindoles as promising drugs for anticancer chemotherapy 243
Synthesis of [1,2]oxazolo[5,4-e]indazoles as antitumour agents 239
Synthesis of isoindolo[1,4]benzoxazinone and isoindolo[1,5]benzoxazepine: two new ring systems of pharmaceutical interest 237
Bioactive pyrrole-based compounds with target selectivity 222
Synthesis and antiproliferative activity of thiazolyl-bis-pyrrolo[2,3-b]pyridines and indolyl-thiazolyl-pyrrolo[2,3-c]pyridines, nortopsentin analogues 217
Pyrazolo[3,4-h]quinolines promising photosensitizing agents in the treatment of cancer 217
An overview on the recent developments of 1,2,4-triazine derivatives as anticancer compounds 212
Synthesis and antiproliferative mechanism of action of pyrrolo[3′,2′:6,7] cyclohepta[1,2-d]pyrimidin-2-amines as singlet oxygen photosensitizers 211
Water-soluble isoindolo[2,1-a]quinoxalin-6-imines: In vitro antiproliferative activity and molecular mechanism(s) of action 205
2-substituted-[1,3]thiazolo[4,5-e]isoindoles as kinases inhibiting compounds 203
Synthesis of pyrazolo[4,3-c][1,2,6]benzothiadiazocine,a new ring system as potential COX inhibitor 202
Pyrano[2,3-e]isoindol-2-ones, new angelicin heteroanalogues 197
Convenient synthesis of pyrrolo[3,4-g]indazole 196
Synthesis and antiproliferative activity of substituted 3[2-(1H-indol-3-yl)-1,3-thiazol-4-yl]-1H-pyrrolo[3,2-b]pyridines, marine alkaloid nortopsentin analogues 194
4,5,6,9-TETRAHYDROPYRROLO[2',3'-3,4]CYCLOEPTA[1,2-d]ISOSSAZOLE, PROCESS FOR THEIR PRODUCTION AND THEIR USES AS ANTITUMOR AGENTS 193
New Thiazole Nortopsentin Analogues Inhibit Bacterial Biofilm Formation 192
Synthesis and Antiproliferative Activity of the Ring System[1,2]Oxazolo[4,5-g]indole 187
Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors 187
Citrus wastewater as a source of value‐added products: Quali‐quantitative analysis and in vitro screening on breast cancer cell lines 185
‘Interrupted’ diazotization of 3-aminoindoles and 3-aminopyrroles 184
Composti a struttura ossazolica, procedimenti per la loro produzione e loro impiego per la cura di patologie a carattere iperproliferativo 181
Pharmaceutical Approaches to Target Antibiotic Resistance Mechanisms 179
NUOVI COMPOSTI PIRAZOLO[3,4-H]CHINOLINICI, LORO PREPARAZIONE ED USO MEDICO 176
Synthesis of substituted isoindolo[2,1-a]quinoxalin-6-yl–amino and 6-imino-5-yl thiourea derivatives 175
GPCR Inhibition in Treating Lymphoma 174
Evaluation of [1,2]oxazolo[5,4-e]isoindoles in lymphoma cells 173
New Tripentone Analogs with Antiproliferative Activity 170
4,5,6,9-tetraidropirrolo[2',3':3,4] cicloepta[1,2-d] isossazoli, procedimento per la loro produzione e loro uso come antitumorali 164
Pyrrolo[3′,2′:6,7]cyclohepta[1,2-b]pyridines with potent photo-antiproliferative activity 163
Pyrrolo[2',3':3,4]cyclohepta[1,2-d][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types 163
Quality characteristics and in vitro digestibility study of barley flour enriched ditalini pasta 162
Synthesis and Antiproliferative Activity of 2,5-bis(3′-Indolyl)pyrroles, Analogues of the Marine Alkaloid Nortopsentin 161
Investigation of Isoindolo[2,1-a] quinoxaline-6-imines as Topoisomerase I Inhibitors with Molecular Modeling Methods 161
Synthesis of the new ring system 6,8-dihydro-5H-pyrrolo[3,4-h]quinazoline 158
Synthesis of the new oligopeptide pyrrole derivative isonetropsin and its one pyrrole unit analogue 158
Marine Anticancer Agents: An Overview with a Particular Focus on Their Chemical Classes 158
Synthesis of a new class of pyrrolo[3,4-h]quinazolines with antimitotic activity 157
Synthesis of 5H-pyrido[3,2-b]pyrrolizin-5-one tripentone analogs with antitumor activity 157
Preclinical Activity of New [1,2]Oxazolo[5,4-e]isoindole Derivatives in Diffuse Malignant Peritoneal Mesothelioma 155
Synthesis of the New Ring System Bispyrido[4',3':4,5]pyrrolo [1,2-a:1',2'-d]pyrazine and Its Deaza Analogue 154
An overview on chemical structures as ΔF508-CFTR correctors 153
Exploring the anticancer activity and the mechanism of action of pyrrolomycins F obtained by microwave-assisted total synthesis 152
Synthesis and biological evaluation of pyrrolo[3’,2’:6,7]cyclohepta[1,2-d]pyrimidin-2-amines 151
Furocoumarins as multi-target agents in the treatment of cystic fibrosis 151
Synthesis, antitumor activity and CDK1 inhibiton of new thiazole nortopsentin analogues 149
Evaluation of Fused Pyrrolothiazole Systems as Correctors of Mutant CFTR Protein 146
Novel 1H‑Pyrrolo[2,3‑b]pyridine Derivative Nortopsentin Analogues: Synthesis and Antitumor Activity in Peritoneal Mesothelioma Experimental Models 145
Editorial: Emerging heterocycles as bioactive compounds 144
THE KEY ROLE OF THE CLINICAL PHARMACIST IN THE MANAGEMENT OF ANTICANCER THERAPIES: A PILOT STUDY IN THE TREATMENT OF PATIENTS WITH NON-SMALL CELL LUNG CANCER 139
Insight on pyrimido[5,4-g]indolizine and pyrimido[4,5-c]pyrrolo[1,2-a]azepine systems as promising photosensitizers on malignant cells 139
Chaperoning system: Intriguing target to modulate the expression of CFTR in cystic fibrosis 138
A Convenient Synthesis of Pyrano[2,3-e]isoindol-2-one : a new heteroanalogue of angelicin 137
Biological evaluation of Pyrrolo[3,4-h]quinazolines 137
NUOVI AGENTI TERAPEUTICI PER IL TRATTAMENTO DI PATOLOGIE EMATOLOGICHE 137
Synthesis and antitumor activities of 1,2,3-triazines and their benzo- and heterofused derivatives 136
Synthesis and photocytotoxic activity of [1,2,3]triazolo[4,5-h][1,6]naphthyridines and [1,3]oxazolo[5,4-h][1,6]naphthyridines 135
Insight into non-nucleoside triazole-based systems as viral polymerases inhibitors 130
Transcriptome and computational analysis assess the anti-tubulin activity of [1,2]oxazole derivatives in lymphoma 128
In vitro digestion of beta glucan enriched pasta: polysaccharide molecular characterization and antioxidant activity of bioaccessible fraction. 128
Novel tricyclic pyrrolo-quinolines as pharmacological correctors of the mutant CFTR chloride channel 127
SYNTHESIS OF PYRROLO[3,4-H]QUINAZOLIN-2-ONE A NEW RING SYSTEM WITH POTENTIAL PHOTOTHERAPEUTIC ACTIVITY 125
Isoxazolo[5,4-e]isoindole a new ring system with potent antitumor activity 125
PYRANO[2,3-E]ISOINDOL-2-ONE: A NEW RING SYSTEM WITH POTENTIAL PHOTOBIOLOGICAL PROPERTIES 124
Identification of 6,9-dihydro-5H-pyrrolo[3,2-h]quinazolines as a new class of F508del-CFTR correctors for the treatment of cystic fibrosis 120
SINTESI DI NUOVI DERIVATI[2,3-E]ISOINDOL-2-ONI A POTENZIALE ATTIVITA' FOTOCHEMIOTERAPICA 118
Recurrence of the oxazole motif in tubulin colchicine site inhibitors with anti-tumor activity 118
PYRROLO[3,4-H]QUINAZOLINES WITH ANTITUMOR ACTIVITY 117
Pyrazolo[3,4-h]quinolin-2-ones with photobiological properties 113
Modulators of anion channels and transporters as alternative therapeutic agents to normalize airway surface liquid in cystic fibrosis 112
Novel insights on [1,2]oxazolo[5,4‐e]isoindoles on multidrug resistant acute myeloid leukemia cell line 110
Identification of pyrrolo[3′,4’:3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas 107
Pyrrolo-fused heterocycles as photochemotherapeutic agents 107
New topoisomerase I inhibitors with condensed-azaindole structure 107
ISOXAZOLO[5,4-E]ISOINDOLE: A NEW RING SYSTEM WITH POTETIAL PHOTOBIOLOGICAL PROPERTIES 104
New tricyclic systems as photosensitizers towards triple negative breast cancer cells 103
In silico-guided exploration of SIRT6 modulation: Discovery of new fragments hits inhibitors 103
In vitro digestion of beta glucan enriched pasta and antioxidant potential of digesta 99
Quality characteristic and in vitro digestibility study of barley flour enriched ditalini pasta 99
Development of [1,2]oxazoloisoindoles tubulin polymerization inhibitors: Further chemical modifications and potential therapeutic effects against lymphomas 96
SYNTHESIS AND PHOTOBIOLOGICAL ACTIVITY OF PYRROLO-FUSED HETEROCYCLES 95
NEW THERAPEUTIC AGENTS FOR THE TREATMENT OF HAEMATOLOGICAL PATHOLOGIES 94
HETEROCYCLIC COMPOUNDS AND MEDICAL USE THEREOF 90
Synthesis of 2H-Imidazo[2′,1':2,3] [1,3]thiazolo[4,5-e]isoindol-8-yl-phenylureas with promising therapeutic features for the treatment of acute myeloid leukemia (AML) with FLT3/ITD mutations 86
Synthesis and antitumor activity of new 7-azaindole derivative nortopsentin analogues 84
The New Microtubule-Targeting Agent SIX2G Induces Immunogenic Cell Death in Multiple Myeloma 83
Pirazolo[3,4-h]chinoline come nuova classe di agenti fotosensibilizzanti 83
Pyrrolocycloheptaoxazole as potent antitumor agents 81
Microwave‐Enhanced Synthesis of 2‐Styrylquinoline‐4‐Carboxamides With Promising Anti‐Lymphoma Activity 70
Totale 16.488
Categoria #
all - tutte 60.376
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 60.376


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.224 141 243 27 27 20 36 54 40 199 171 56 210
2022/20231.353 158 223 27 101 165 196 64 92 139 59 100 29
2023/2024752 39 95 42 72 57 94 92 59 8 24 29 141
2024/20252.057 88 111 130 173 69 77 200 185 158 219 246 401
2025/20265.850 381 201 421 497 527 763 871 644 492 555 247 251
2026/20278 8 0 0 0 0 0 0 0 0 0 0 0
Totale 16.558