Archivio istituzionale della ricerca dell'Università degli Studi di Palermo

SPINELLO, Angelo
 Distribuzione geografica
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Continente #
NA - Nord America 2.828
EU - Europa 1.063
AS - Asia 396
AF - Africa 23
SA - Sud America 9
Continente sconosciuto - Info sul continente non disponibili 1
Totale 4.320
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Nazione #
US - Stati Uniti d'America 2.815
IT - Italia 495
CN - Cina 180
SG - Singapore 153
FI - Finlandia 142
IE - Irlanda 94
DE - Germania 86
GB - Regno Unito 54
SE - Svezia 47
RU - Federazione Russa 43
IN - India 26
FR - Francia 20
UA - Ucraina 20
CI - Costa d'Avorio 15
RO - Romania 11
ES - Italia 10
BE - Belgio 9
HK - Hong Kong 9
PL - Polonia 9
CA - Canada 8
NL - Olanda 8
BR - Brasile 5
IL - Israele 5
KR - Corea 5
AT - Austria 4
CY - Cipro 4
SA - Arabia Saudita 4
CH - Svizzera 3
IR - Iran 3
JP - Giappone 3
MX - Messico 3
SC - Seychelles 3
CL - Cile 2
CO - Colombia 2
CU - Cuba 2
LB - Libano 2
MA - Marocco 2
NG - Nigeria 2
PT - Portogallo 2
A1 - Anonimo 1
AL - Albania 1
BG - Bulgaria 1
DZ - Algeria 1
HR - Croazia 1
KZ - Kazakistan 1
LT - Lituania 1
MN - Mongolia 1
NO - Norvegia 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 4.320
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Città #
Fairfield 415
Ashburn 246
Chandler 244
Woodbridge 219
Seattle 175
Ann Arbor 168
Houston 166
Wilmington 162
Cambridge 144
Singapore 127
Palermo 124
Dublin 94
Medford 82
Altamura 62
Santa Clara 60
Princeton 56
Lawrence 47
Nanjing 40
San Diego 29
Dearborn 27
Boardman 22
New York 21
Piscataway 20
Ludwigshafen am Rhein 19
Rome 19
Beijing 18
Changsha 16
Abidjan 15
Milan 15
Nanchang 15
London 14
San Paolo di Civitate 14
Ningbo 13
Shenyang 12
Tianjin 11
Des Moines 10
Kumar 10
Sciacca 10
Brussels 9
Helsinki 9
Naples 9
Napoli 9
Trieste 9
Frankfurt 8
Jacksonville 8
Jinan 8
Kilburn 8
Aversa 7
Berlin 7
Chicago 7
Derio 7
Hebei 7
Munich 7
Redwood City 7
Saint Petersburg 7
Atlanta 6
Verona 6
Jiaxing 5
Los Angeles 5
Paris 5
Phoenix 5
Taizhou 5
Tulsa 5
Cagliari 4
Central 4
Guangzhou 4
Haikou 4
Hangzhou 4
Hong Kong 4
Lappeenranta 4
Moscow 4
Nicosia 4
North Kansas City 4
Polska 4
Riyadh 4
Seongnam 4
Toronto 4
Bangalore 3
Bremen 3
Campinas 3
Düsseldorf 3
Erice 3
Falls Church 3
Ivry-sur-Seine 3
Little Rock 3
Monreale 3
Muenster 3
Orange 3
Partinico 3
Philadelphia 3
Vienna 3
Washington 3
Zhengzhou 3
Acton 2
Amsterdam 2
Auburn Hills 2
Bogotá 2
Carini 2
Chennai 2
Cosenza 2
Totale 3.254
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Nome #
Antimicrobial and Antibiofilm Activity of a Recombinant Fragment of β-Thymosin of Sea Urchin Paracentrotus lividus 214
DNA-Binding and Anticancer Activity of Pyrene-Imidazolium Derivatives 207
A Synthetic Derivative of Antimicrobial Peptide Holothuroidin 2 from Mediterranean Sea Cucumber (Holothuria tubulosa) in the Control of Listeria monocytogenes 185
Enhancement of premature stop codon readthrough in the CFTR gene by Ataluren (PTC124) derivatives 183
Toward a Rationale for the PTC124 (Ataluren) Promoted Readthrough of Premature Stop Codons: A Computational Approach and GFP-Reporter Cell-Based Assay 181
The Interaction of Metal Complexes with G-quadruplex DNA 173
The Binding Mechanism of Epolactaene to Hsp60 Unveiled by in Silico Modelling 171
(Dipyrido[3,2-a:2',3'-c]phenazine)(glycinato)copper(II) perchlorate: A novel DNA-intercalator with anti-proliferative activity against thyroid cancer cell lines 170
G-quadruplex vs. duplex-DNA binding of nickel(II) and zinc(II) Schiff base complexes 151
A peptide from human β thymosin as a platform for the development of new anti-biofilm agents for Staphylococcus spp. and Pseudomonas aeruginosa 150
Paracentrin 1, a synthetic antimicrobial peptide from the sea-urchin Paracentrotus lividus, interferes with staphylococcal and Pseudomonas aeruginosa biofilm formation 139
The interaction of Schiff Base complexes of nickel(II) and zinc(II) with duplex and G-quadruplex DNA 136
A Theoretical and Experimental Investigation of the Spectroscopic Properties of a DNA-Intercalator Salphen-Type ZnIIComplex 134
Quaternary structures of GroEL and naïve-Hsp60 chaperonins in solution: A combined SAXS-MD study 129
Circular Dichroism of DNA G-Quadruplexes: Combining Modeling and Spectroscopy to Unravel Complex Structures 129
Nickel(II), copper(II) and zinc(II) metallo-intercalators: structural details of the DNA-binding by a combined experimental and computational investigation 128
Metal ions and metal complexes in Alzheimer’s disease 118
Molecular recognition of naphthalene diimide ligands by telomeric quadruplex-DNA: The importance of the protonation state and mediated hydrogen bonds 112
The Right Answer for the Right Electrostatics: Force Field Methods Are Able to Describe Relative Energies of DNA Guanine Quadruplexes 103
The inhibition of glycerol permeation through aquaglyceroporin-3 induced by mercury(II): A molecular dynamics study 101
Metal Complex–DNA Binding: Insights from Molecular Dynamics and DFT/MM Calculations 100
Selective G-Quadruplex Stabilizers: Schiff-base Metal Complexes with Anticancer Activity 87
Targeting G-quadruplexes with organic dyes: Chelerythrine–DNA binding elucidated by combining molecular modeling and optical spectroscopy 87
The Interaction of Small Molecules with Biomolecules 84
G4-DNA vs. B-DNA binding of Schiff base transition metal complexes 65
The interaction of DNA with metal complexes: experimental and computational studies 64
Frontiers of metal-coordinating drug design 64
NiII, and ZnII Schiff Base Complexes: Telomeric G-quadruplex Stabilizers 63
Novel half Salphen cobalt(III) complexes: synthesis, DNA binding and anticancer studies 61
DNA-Binding of NiII, CuII and ZnII Complexes of Salen Derivatives 52
Ni(II) and Zn(II) Schiff Base complexes: B-DNA vs G4-DNA binding 49
The catalytic mechanism of steroidogenic cytochromes P450 from all-atom simulations: Entwinement with membrane environment, redox partners, and post-transcriptional regulation 48
The interaction of DNA with metal complexes: computational investigations 45
Allosteric Cross-Talk among Spike’s Receptor-Binding Domain Mutations of the SARS-CoV-2 South African Variant Triggers an Effective Hijacking of Human Cell Receptor 45
Exploiting Cryo-EM Structural Information and All-Atom Simulations to Decrypt the Molecular Mechanism of Splicing Modulators 43
All-Atom simulations disclose how cytochrome reductase reshapes the substrate access/egress routes of its partner cyp450s 42
Balanced dual acting compounds targeting aromatase and estrogen receptor α as an emerging therapeutic opportunity to counteract estrogen responsive breast cancer 40
Recent advances in computational design of potent aromatase inhibitors: open-eye on endocrine-resistant breast cancers 38
A Dehydrogenase Dual Hydrogen Abstraction Mechanism Promotes Estrogen Biosynthesis: Can We Expand the Functional Annotation of the Aromatase Enzyme? 37
All-atom simulations to studying metallodrugs/target interactions 37
Molecular Basis of SARS-CoV-2 Nsp1-Induced Immune Translational Shutdown as Revealed by All-Atom Simulations 36
A Novel Peptide with Antifungal Activity from Red Swamp Crayfish Procambarus clarkii 35
A Computational Assay of Estrogen Receptor α Antagonists Reveals the Key Common Structural Traits of Drugs Effectively Fighting Refractory Breast Cancers 35
Computing Metal-Binding Proteins for Therapeutic Benefit 34
How the Metal Ion Affects the 1H NMR Chemical Shift Values of Schiff Base Metal Complexes: Rationalization by DFT Calculations 32
Can multiscale simulations unravel the function of metallo-enzymes to improve knowledge-based drug discovery? 31
All-atom simulations disentangle the functional dynamics underlying gene maturation in the intron lariat spliceosome 31
How Can Interleukin-1 Receptor Antagonist Modulate Distinct Cell Death Pathways? 31
An omics perspective to the molecular mechanisms of anticancer metallo-drugs in the computational microscope era 27
Is the Rigidity of SARS-CoV-2 Spike Receptor-Binding Motif the Hallmark for Its Enhanced Infectivity? Insights from All-Atom Simulations 26
Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment 24
Molecular basis for endocrine disruption by pesticides targeting aromatase and estrogen receptor 22
Investigating the molecular mechanism of h3b‐8800: A splicing modulator inducing preferential lethality in spliceosome‐mutant cancers 22
Anticancer Activity, Reduction Mechanism and G-Quadruplex DNA Binding of a Redox-Activated Platinum(IV)–Salphen Complex 21
Targeting Orthosteric and Allosteric Pockets of Aromatase via Dual-Mode Novel Azole Inhibitors 21
Post-Translational Regulation of CYP450s Metabolism As Revealed by All-Atoms Simulations of the Aromatase Enzyme 20
Molecular Mechanisms of the Blockage of Glioblastoma Motility 20
The avidin-theophylline complex: A structural and computational study 18
Mechanism of the Covalent Inhibition of Human Transmembrane Protease Serine 2 as an Original Antiviral Strategy 18
Structural, Thermodynamic, and Kinetic Traits of Antiestrogen-Compounds Selectively Targeting the Y537S Mutant Estrogen Receptor α Transcriptional Activity in Breast Cancer Cell Lines 18
Rational design of allosteric modulators of the aromatase enzyme: An unprecedented therapeutic strategy to fight breast cancer 17
Role of computational and structural biology in the development of small-molecule modulators of the spliceosome 16
Predicting the Three-Dimensional Structure of the c-KIT Proto-Oncogene Promoter and the Dynamics of Its Strongly Coupled Guanine Quadruplexes 16
Single-digit nanomolar inhibitors lock the aromatase active site via a dualsteric targeting strategy 16
Cancer-Related Mutations Alter RNA-Driven Functional Cross-Talk Underlying Premature-Messenger RNA Recognition by Splicing Factor SF3b 14
Totale 4.766
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Categoria #
all - tutte 21.879
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 21.879
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020824 0 0 0 122 123 122 107 78 101 61 77 33
2020/2021527 31 42 46 53 38 35 27 47 55 79 33 41
2021/2022783 33 87 31 17 6 26 17 221 49 90 68 138
2022/2023821 79 179 11 60 72 144 15 59 106 8 57 31
2023/2024446 32 50 45 31 31 61 70 17 3 3 25 78
2024/2025404 78 209 110 7 0 0 0 0 0 0 0 0
Totale 4.766