Archivio istituzionale della ricerca dell'Università degli Studi di Palermo

SPINELLO, Angelo
 Distribuzione geografica
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Continente #
NA - Nord America 5.269
EU - Europa 2.547
AS - Asia 2.210
SA - Sud America 552
Continente sconosciuto - Info sul continente non disponibili 503
AF - Africa 89
OC - Oceania 3
Totale 11.173
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Nazione #
US - Stati Uniti d'America 5.096
IT - Italia 762
RU - Federazione Russa 723
SG - Singapore 698
CN - Cina 565
BR - Brasile 431
HK - Hong Kong 232
VN - Vietnam 216
FI - Finlandia 169
PL - Polonia 164
DE - Germania 150
FR - Francia 124
GB - Regno Unito 109
IE - Irlanda 100
CA - Canada 85
BD - Bangladesh 83
JP - Giappone 72
IN - India 68
SE - Svezia 63
KR - Corea 49
AR - Argentina 41
IL - Israele 36
UA - Ucraina 36
ES - Italia 35
MX - Messico 33
NL - Olanda 33
IQ - Iraq 28
TR - Turchia 22
AT - Austria 19
VE - Venezuela 18
CI - Costa d'Avorio 17
CO - Colombia 17
PK - Pakistan 16
NP - Nepal 15
SA - Arabia Saudita 15
EC - Ecuador 14
MA - Marocco 14
ZA - Sudafrica 14
RO - Romania 13
JM - Giamaica 11
ID - Indonesia 10
SC - Seychelles 10
BE - Belgio 9
DZ - Algeria 8
HN - Honduras 8
MY - Malesia 8
PY - Paraguay 8
UY - Uruguay 8
CR - Costa Rica 7
JO - Giordania 7
PE - Perù 7
AE - Emirati Arabi Uniti 6
EG - Egitto 6
GT - Guatemala 6
KE - Kenya 6
LT - Lituania 6
UZ - Uzbekistan 6
CL - Cile 5
CY - Cipro 5
KZ - Kazakistan 5
LB - Libano 5
TH - Thailandia 5
TT - Trinidad e Tobago 5
BH - Bahrain 4
DO - Repubblica Dominicana 4
OM - Oman 4
PH - Filippine 4
AZ - Azerbaigian 3
BG - Bulgaria 3
CH - Svizzera 3
CZ - Repubblica Ceca 3
IR - Iran 3
KG - Kirghizistan 3
MN - Mongolia 3
NG - Nigeria 3
NI - Nicaragua 3
PT - Portogallo 3
QA - Qatar 3
RS - Serbia 3
AU - Australia 2
BO - Bolivia 2
CU - Cuba 2
DK - Danimarca 2
EE - Estonia 2
ET - Etiopia 2
GE - Georgia 2
HR - Croazia 2
IS - Islanda 2
KH - Cambogia 2
MM - Myanmar 2
SK - Slovacchia (Repubblica Slovacca) 2
SN - Senegal 2
SV - El Salvador 2
TN - Tunisia 2
A1 - Anonimo 1
AL - Albania 1
AM - Armenia 1
AO - Angola 1
BB - Barbados 1
BW - Botswana 1
Totale 10.650
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Città #
Ashburn 732
Singapore 460
San Jose 453
Fairfield 415
Chandler 244
Hong Kong 225
Palermo 220
Woodbridge 219
Houston 180
Seattle 178
Ann Arbor 168
Wilmington 163
Cambridge 144
Zgierz 140
Moscow 123
Beijing 115
Council Bluffs 111
Santa Clara 106
Dublin 100
Dallas 90
Medford 82
Ho Chi Minh City 69
Tokyo 69
Lauterbourg 65
Los Angeles 65
New York 63
Altamura 62
Chicago 58
Princeton 56
Hanoi 54
Lawrence 47
Hefei 46
Nanjing 45
Boardman 43
Milan 41
Buffalo 39
Rome 34
Toronto 34
Helsinki 31
São Paulo 30
San Diego 29
Dearborn 27
Frankfurt am Main 27
Atlanta 23
London 22
Piscataway 21
The Dalles 21
Changsha 20
Ludwigshafen am Rhein 19
Orem 19
Abidjan 17
Denver 17
Nanchang 17
Phoenix 17
Montreal 16
Munich 16
Amsterdam 15
Naples 15
Washington 15
Paris 14
San Paolo di Civitate 14
Tianjin 14
Chennai 13
Ningbo 13
Porto Alegre 13
Brooklyn 12
Campinas 12
Mumbai 12
Shenyang 12
Charlotte 11
Des Moines 11
Rio de Janeiro 11
Vienna 11
Belo Horizonte 10
Brasília 10
Kumar 10
Mexico City 10
Nuremberg 10
Riyadh 10
Sciacca 10
Seoul 10
Warsaw 10
Brussels 9
Haiphong 9
Jinan 9
Napoli 9
Redondo Beach 9
San Francisco 9
Shanghai 9
Stockholm 9
Trieste 9
Boydton 8
Columbus 8
Frankfurt 8
Jacksonville 8
Johannesburg 8
Kilburn 8
Memphis 8
Philadelphia 8
Poplar 8
Totale 6.408
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Nome #
(Dipyrido[3,2-a:2',3'-c]phenazine)(glycinato)copper(II) perchlorate: A novel DNA-intercalator with anti-proliferative activity against thyroid cancer cell lines 333
DNA-Binding and Anticancer Activity of Pyrene-Imidazolium Derivatives 332
Antimicrobial and Antibiofilm Activity of a Recombinant Fragment of β-Thymosin of Sea Urchin Paracentrotus lividus 327
A Synthetic Derivative of Antimicrobial Peptide Holothuroidin 2 from Mediterranean Sea Cucumber (Holothuria tubulosa) in the Control of Listeria monocytogenes 327
A peptide from human β thymosin as a platform for the development of new anti-biofilm agents for Staphylococcus spp. and Pseudomonas aeruginosa 322
Novel half Salphen cobalt(III) complexes: synthesis, DNA binding and anticancer studies 292
Enhancement of premature stop codon readthrough in the CFTR gene by Ataluren (PTC124) derivatives 292
The Interaction of Metal Complexes with G-quadruplex DNA 278
Toward a Rationale for the PTC124 (Ataluren) Promoted Readthrough of Premature Stop Codons: A Computational Approach and GFP-Reporter Cell-Based Assay 262
A Theoretical and Experimental Investigation of the Spectroscopic Properties of a DNA-Intercalator Salphen-Type ZnIIComplex 244
Nickel(II), copper(II) and zinc(II) metallo-intercalators: structural details of the DNA-binding by a combined experimental and computational investigation 243
Circular Dichroism of DNA G-Quadruplexes: Combining Modeling and Spectroscopy to Unravel Complex Structures 229
The Binding Mechanism of Epolactaene to Hsp60 Unveiled by in Silico Modelling 228
G-quadruplex vs. duplex-DNA binding of nickel(II) and zinc(II) Schiff base complexes 226
Paracentrin 1, a synthetic antimicrobial peptide from the sea-urchin Paracentrotus lividus, interferes with staphylococcal and Pseudomonas aeruginosa biofilm formation 223
The interaction of Schiff Base complexes of nickel(II) and zinc(II) with duplex and G-quadruplex DNA 197
Ni(II) and Zn(II) Schiff Base complexes: B-DNA vs G4-DNA binding 195
NiII, and ZnII Schiff Base Complexes: Telomeric G-quadruplex Stabilizers 192
The Interaction of Small Molecules with Biomolecules 181
Quaternary structures of GroEL and naïve-Hsp60 chaperonins in solution: A combined SAXS-MD study 181
Metal ions and metal complexes in Alzheimer’s disease 177
Allosteric Cross-Talk among Spike’s Receptor-Binding Domain Mutations of the SARS-CoV-2 South African Variant Triggers an Effective Hijacking of Human Cell Receptor 174
Selective G-Quadruplex Stabilizers: Schiff-base Metal Complexes with Anticancer Activity 171
A Novel Peptide with Antifungal Activity from Red Swamp Crayfish Procambarus clarkii 169
The Right Answer for the Right Electrostatics: Force Field Methods Are Able to Describe Relative Energies of DNA Guanine Quadruplexes 168
Molecular recognition of naphthalene diimide ligands by telomeric quadruplex-DNA: The importance of the protonation state and mediated hydrogen bonds 162
G4-DNA vs. B-DNA binding of Schiff base transition metal complexes 161
Metal Complex–DNA Binding: Insights from Molecular Dynamics and DFT/MM Calculations 159
DNA-Binding of NiII, CuII and ZnII Complexes of Salen Derivatives 152
The inhibition of glycerol permeation through aquaglyceroporin-3 induced by mercury(II): A molecular dynamics study 148
DNA Binding Activity of Functionalized Schiff Base Metal Complexes 147
The interaction of DNA with metal complexes: experimental and computational studies 146
How the Metal Ion Affects the 1H NMR Chemical Shift Values of Schiff Base Metal Complexes: Rationalization by DFT Calculations 142
Resolving the Structure of a Guanine Quadruplex in TMPRSS2 Messenger RNA by Circular Dichroism and Molecular Modeling 137
Targeting G-quadruplexes with organic dyes: Chelerythrine–DNA binding elucidated by combining molecular modeling and optical spectroscopy 136
Rationalizing the structural basis of organic-platinum hybrid complexes binding towards quadruplex-duplex hybrids through all-atom simulations 135
Mechanism of the Covalent Inhibition of Human Transmembrane Protease Serine 2 as an Original Antiviral Strategy 130
Unraveling the molecular basis for G‐quadruplex‐binders to ALS/FTD‐associated G4C2 repeats of the C9orf72 gene 126
Frontiers of metal-coordinating drug design 125
Epigallocatechin-3-gallate binds tandem RNA recognition motifs of TDP-43 and inhibits its aggregation 120
Predicting the Three-Dimensional Structure of the c-KIT Proto-Oncogene Promoter and the Dynamics of Its Strongly Coupled Guanine Quadruplexes 119
Metal centers and aromatic moieties in Schiff base complexes: impact on G-quadruplex stabilization and oncogene downregulation 117
Balanced dual acting compounds targeting aromatase and estrogen receptor α as an emerging therapeutic opportunity to counteract estrogen responsive breast cancer 117
Computational modeling and experimental validation of the interaction between tumor biomarker mesothelin and an engineered targeting protein with therapeutic activity 114
Anticancer Activity, Reduction Mechanism and G-Quadruplex DNA Binding of a Redox-Activated Platinum(IV)–Salphen Complex 113
All-Atom simulations disclose how cytochrome reductase reshapes the substrate access/egress routes of its partner cyp450s 113
All-atom simulations disentangle the functional dynamics underlying gene maturation in the intron lariat spliceosome 112
The catalytic mechanism of steroidogenic cytochromes P450 from all-atom simulations: Entwinement with membrane environment, redox partners, and post-transcriptional regulation 111
A Dehydrogenase Dual Hydrogen Abstraction Mechanism Promotes Estrogen Biosynthesis: Can We Expand the Functional Annotation of the Aromatase Enzyme? 110
A Computational Assay of Estrogen Receptor α Antagonists Reveals the Key Common Structural Traits of Drugs Effectively Fighting Refractory Breast Cancers 110
All-atom simulations to studying metallodrugs/target interactions 109
Is the Rigidity of SARS-CoV-2 Spike Receptor-Binding Motif the Hallmark for Its Enhanced Infectivity? Insights from All-Atom Simulations 107
Can multiscale simulations unravel the function of metallo-enzymes to improve knowledge-based drug discovery? 107
How Can Interleukin-1 Receptor Antagonist Modulate Distinct Cell Death Pathways? 107
Computing Metal-Binding Proteins for Therapeutic Benefit 104
The interaction of DNA with metal complexes: computational investigations 102
Post-Translational Regulation of CYP450s Metabolism As Revealed by All-Atoms Simulations of the Aromatase Enzyme 95
Exploiting Cryo-EM Structural Information and All-Atom Simulations to Decrypt the Molecular Mechanism of Splicing Modulators 93
An omics perspective to the molecular mechanisms of anticancer metallo-drugs in the computational microscope era 93
Cancer-Related Mutations Alter RNA-Driven Functional Cross-Talk Underlying Premature-Messenger RNA Recognition by Splicing Factor SF3b 92
Recent advances in computational design of potent aromatase inhibitors: open-eye on endocrine-resistant breast cancers 91
Molecular Basis of SARS-CoV-2 Nsp1-Induced Immune Translational Shutdown as Revealed by All-Atom Simulations 88
Targeting Orthosteric and Allosteric Pockets of Aromatase via Dual-Mode Novel Azole Inhibitors 80
The avidin-theophylline complex: A structural and computational study 78
Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment 77
Role of computational and structural biology in the development of small-molecule modulators of the spliceosome 76
Molecular Mechanisms of the Blockage of Glioblastoma Motility 68
Investigating the molecular mechanism of h3b‐8800: A splicing modulator inducing preferential lethality in spliceosome‐mutant cancers 67
Molecular basis for endocrine disruption by pesticides targeting aromatase and estrogen receptor 64
Self-assembling Depsipeptides on Aggregation-Induced Emission Luminogens: A New Way to Create Programmable Nanovesicles and Soft Nanocarriers 59
Rational design of allosteric modulators of the aromatase enzyme: An unprecedented therapeutic strategy to fight breast cancer 59
Single-digit nanomolar inhibitors lock the aromatase active site via a dualsteric targeting strategy 59
Structural, Thermodynamic, and Kinetic Traits of Antiestrogen-Compounds Selectively Targeting the Y537S Mutant Estrogen Receptor α Transcriptional Activity in Breast Cancer Cell Lines 58
Unlocking G4 DNA affinity through aromatic side chains: a comparative study of nickel(ii), copper(ii), and zinc(ii) salnaphen derivatives ), and zinc( ii ) salnaphen derivatives 15
Totale 11.173
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Categoria #
all - tutte 41.518
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 41.518
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022632 0 0 0 17 6 26 17 221 49 90 68 138
2022/2023821 79 179 11 60 72 144 15 59 106 8 57 31
2023/2024446 32 50 45 31 31 61 70 17 3 3 25 78
2024/20251.560 78 209 110 106 53 38 131 96 110 123 166 340
2025/20264.182 309 189 324 435 394 500 558 463 316 293 226 175
2026/20271.069 237 129 434 269 0 0 0 0 0 0 0 0
Totale 11.173