Archivio istituzionale della ricerca dell'Università degli Studi di Palermo

SPINELLO, Angelo
 Distribuzione geografica
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Continente #
NA - Nord America 4.217
EU - Europa 2.440
AS - Asia 2.134
SA - Sud America 519
AF - Africa 87
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 1
Totale 9.401
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Nazione #
US - Stati Uniti d'America 4.130
RU - Federazione Russa 721
IT - Italia 696
SG - Singapore 695
CN - Cina 550
BR - Brasile 417
HK - Hong Kong 231
VN - Vietnam 212
FI - Finlandia 168
PL - Polonia 164
DE - Germania 148
FR - Francia 120
IE - Irlanda 100
GB - Regno Unito 95
JP - Giappone 71
IN - India 67
SE - Svezia 54
BD - Bangladesh 52
KR - Corea 47
CA - Canada 41
AR - Argentina 40
UA - Ucraina 36
ES - Italia 32
NL - Olanda 32
IL - Israele 31
IQ - Iraq 28
MX - Messico 25
TR - Turchia 20
AT - Austria 19
CI - Costa d'Avorio 17
PK - Pakistan 15
SA - Arabia Saudita 15
MA - Marocco 14
NP - Nepal 14
VE - Venezuela 14
RO - Romania 13
ZA - Sudafrica 13
CO - Colombia 11
EC - Ecuador 10
ID - Indonesia 10
BE - Belgio 9
SC - Seychelles 9
DZ - Algeria 8
PY - Paraguay 8
JO - Giordania 7
MY - Malesia 7
UY - Uruguay 7
AE - Emirati Arabi Uniti 6
EG - Egitto 6
KE - Kenya 6
LT - Lituania 6
PE - Perù 6
UZ - Uzbekistan 6
CL - Cile 5
CY - Cipro 5
KZ - Kazakistan 5
LB - Libano 5
BH - Bahrain 4
DO - Repubblica Dominicana 4
OM - Oman 4
PH - Filippine 4
AZ - Azerbaigian 3
BG - Bulgaria 3
CH - Svizzera 3
GT - Guatemala 3
HN - Honduras 3
IR - Iran 3
JM - Giamaica 3
KG - Kirghizistan 3
NG - Nigeria 3
RS - Serbia 3
AU - Australia 2
CR - Costa Rica 2
CU - Cuba 2
CZ - Repubblica Ceca 2
DK - Danimarca 2
ET - Etiopia 2
HR - Croazia 2
IS - Islanda 2
KH - Cambogia 2
MM - Myanmar 2
MN - Mongolia 2
PT - Portogallo 2
QA - Qatar 2
SK - Slovacchia (Repubblica Slovacca) 2
SN - Senegal 2
TN - Tunisia 2
TT - Trinidad e Tobago 2
A1 - Anonimo 1
AL - Albania 1
AM - Armenia 1
AO - Angola 1
BB - Barbados 1
BW - Botswana 1
BY - Bielorussia 1
BZ - Belize 1
CG - Congo 1
GE - Georgia 1
GR - Grecia 1
GY - Guiana 1
Totale 9.391
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Città #
Ashburn 552
Singapore 457
Fairfield 415
San Jose 264
Chandler 244
Hong Kong 224
Woodbridge 219
Palermo 211
Seattle 177
Houston 173
Ann Arbor 168
Wilmington 163
Cambridge 144
Zgierz 140
Moscow 123
Beijing 111
Dublin 100
Santa Clara 84
Medford 82
Dallas 78
Ho Chi Minh City 69
Tokyo 68
Council Bluffs 66
Lauterbourg 65
Altamura 62
Princeton 56
Hanoi 52
Los Angeles 51
New York 50
Lawrence 47
Hefei 46
Nanjing 45
Buffalo 36
Milan 35
Chicago 31
Helsinki 31
Rome 31
San Diego 29
São Paulo 29
Dearborn 27
Frankfurt am Main 25
Boardman 24
Piscataway 21
Atlanta 20
Changsha 20
London 20
Ludwigshafen am Rhein 19
Orem 19
The Dalles 19
Abidjan 17
Munich 16
Amsterdam 15
Nanchang 15
San Paolo di Civitate 14
Tianjin 14
Chennai 13
Ningbo 13
Campinas 12
Denver 12
Montreal 12
Mumbai 12
Phoenix 12
Porto Alegre 12
Shenyang 12
Des Moines 11
Paris 11
Rio de Janeiro 11
Vienna 11
Belo Horizonte 10
Kumar 10
Naples 10
Nuremberg 10
Riyadh 10
Sciacca 10
Toronto 10
Brooklyn 9
Brussels 9
Haiphong 9
Jinan 9
Napoli 9
Redondo Beach 9
Trieste 9
Warsaw 9
Brasília 8
Frankfurt 8
Jacksonville 8
Kilburn 8
Poplar 8
Seoul 8
Shanghai 8
Zhengzhou 8
Ankara 7
Aversa 7
Baghdad 7
Berlin 7
Charlotte 7
Derio 7
Guangzhou 7
Hebei 7
Johannesburg 7
Totale 5.756
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Nome #
(Dipyrido[3,2-a:2',3'-c]phenazine)(glycinato)copper(II) perchlorate: A novel DNA-intercalator with anti-proliferative activity against thyroid cancer cell lines 316
DNA-Binding and Anticancer Activity of Pyrene-Imidazolium Derivatives 311
Antimicrobial and Antibiofilm Activity of a Recombinant Fragment of β-Thymosin of Sea Urchin Paracentrotus lividus 306
A peptide from human β thymosin as a platform for the development of new anti-biofilm agents for Staphylococcus spp. and Pseudomonas aeruginosa 299
A Synthetic Derivative of Antimicrobial Peptide Holothuroidin 2 from Mediterranean Sea Cucumber (Holothuria tubulosa) in the Control of Listeria monocytogenes 293
Enhancement of premature stop codon readthrough in the CFTR gene by Ataluren (PTC124) derivatives 277
Novel half Salphen cobalt(III) complexes: synthesis, DNA binding and anticancer studies 273
Toward a Rationale for the PTC124 (Ataluren) Promoted Readthrough of Premature Stop Codons: A Computational Approach and GFP-Reporter Cell-Based Assay 246
The Interaction of Metal Complexes with G-quadruplex DNA 237
A Theoretical and Experimental Investigation of the Spectroscopic Properties of a DNA-Intercalator Salphen-Type ZnIIComplex 221
G-quadruplex vs. duplex-DNA binding of nickel(II) and zinc(II) Schiff base complexes 214
The Binding Mechanism of Epolactaene to Hsp60 Unveiled by in Silico Modelling 214
Nickel(II), copper(II) and zinc(II) metallo-intercalators: structural details of the DNA-binding by a combined experimental and computational investigation 210
Circular Dichroism of DNA G-Quadruplexes: Combining Modeling and Spectroscopy to Unravel Complex Structures 209
Paracentrin 1, a synthetic antimicrobial peptide from the sea-urchin Paracentrotus lividus, interferes with staphylococcal and Pseudomonas aeruginosa biofilm formation 195
The interaction of Schiff Base complexes of nickel(II) and zinc(II) with duplex and G-quadruplex DNA 185
Quaternary structures of GroEL and naïve-Hsp60 chaperonins in solution: A combined SAXS-MD study 161
Metal ions and metal complexes in Alzheimer’s disease 160
NiII, and ZnII Schiff Base Complexes: Telomeric G-quadruplex Stabilizers 159
A Novel Peptide with Antifungal Activity from Red Swamp Crayfish Procambarus clarkii 157
The Interaction of Small Molecules with Biomolecules 156
Allosteric Cross-Talk among Spike’s Receptor-Binding Domain Mutations of the SARS-CoV-2 South African Variant Triggers an Effective Hijacking of Human Cell Receptor 151
Molecular recognition of naphthalene diimide ligands by telomeric quadruplex-DNA: The importance of the protonation state and mediated hydrogen bonds 149
The Right Answer for the Right Electrostatics: Force Field Methods Are Able to Describe Relative Energies of DNA Guanine Quadruplexes 147
Metal Complex–DNA Binding: Insights from Molecular Dynamics and DFT/MM Calculations 146
The inhibition of glycerol permeation through aquaglyceroporin-3 induced by mercury(II): A molecular dynamics study 137
G4-DNA vs. B-DNA binding of Schiff base transition metal complexes 135
The interaction of DNA with metal complexes: experimental and computational studies 132
Ni(II) and Zn(II) Schiff Base complexes: B-DNA vs G4-DNA binding 132
Selective G-Quadruplex Stabilizers: Schiff-base Metal Complexes with Anticancer Activity 131
How the Metal Ion Affects the 1H NMR Chemical Shift Values of Schiff Base Metal Complexes: Rationalization by DFT Calculations 130
Targeting G-quadruplexes with organic dyes: Chelerythrine–DNA binding elucidated by combining molecular modeling and optical spectroscopy 127
Resolving the Structure of a Guanine Quadruplex in TMPRSS2 Messenger RNA by Circular Dichroism and Molecular Modeling 124
DNA-Binding of NiII, CuII and ZnII Complexes of Salen Derivatives 124
DNA Binding Activity of Functionalized Schiff Base Metal Complexes 123
Mechanism of the Covalent Inhibition of Human Transmembrane Protease Serine 2 as an Original Antiviral Strategy 115
Frontiers of metal-coordinating drug design 115
Unraveling the molecular basis for G‐quadruplex‐binders to ALS/FTD‐associated G4C2 repeats of the C9orf72 gene 111
Rationalizing the structural basis of organic-platinum hybrid complexes binding towards quadruplex-duplex hybrids through all-atom simulations 110
Balanced dual acting compounds targeting aromatase and estrogen receptor α as an emerging therapeutic opportunity to counteract estrogen responsive breast cancer 105
The catalytic mechanism of steroidogenic cytochromes P450 from all-atom simulations: Entwinement with membrane environment, redox partners, and post-transcriptional regulation 103
All-atom simulations disentangle the functional dynamics underlying gene maturation in the intron lariat spliceosome 102
Epigallocatechin-3-gallate binds tandem RNA recognition motifs of TDP-43 and inhibits its aggregation 101
All-atom simulations to studying metallodrugs/target interactions 100
Anticancer Activity, Reduction Mechanism and G-Quadruplex DNA Binding of a Redox-Activated Platinum(IV)–Salphen Complex 99
Predicting the Three-Dimensional Structure of the c-KIT Proto-Oncogene Promoter and the Dynamics of Its Strongly Coupled Guanine Quadruplexes 99
All-Atom simulations disclose how cytochrome reductase reshapes the substrate access/egress routes of its partner cyp450s 99
A Dehydrogenase Dual Hydrogen Abstraction Mechanism Promotes Estrogen Biosynthesis: Can We Expand the Functional Annotation of the Aromatase Enzyme? 99
The interaction of DNA with metal complexes: computational investigations 98
A Computational Assay of Estrogen Receptor α Antagonists Reveals the Key Common Structural Traits of Drugs Effectively Fighting Refractory Breast Cancers 97
Metal centers and aromatic moieties in Schiff base complexes: impact on G-quadruplex stabilization and oncogene downregulation 96
Can multiscale simulations unravel the function of metallo-enzymes to improve knowledge-based drug discovery? 96
Computing Metal-Binding Proteins for Therapeutic Benefit 93
How Can Interleukin-1 Receptor Antagonist Modulate Distinct Cell Death Pathways? 92
Is the Rigidity of SARS-CoV-2 Spike Receptor-Binding Motif the Hallmark for Its Enhanced Infectivity? Insights from All-Atom Simulations 91
Computational modeling and experimental validation of the interaction between tumor biomarker mesothelin and an engineered targeting protein with therapeutic activity 84
Cancer-Related Mutations Alter RNA-Driven Functional Cross-Talk Underlying Premature-Messenger RNA Recognition by Splicing Factor SF3b 83
Exploiting Cryo-EM Structural Information and All-Atom Simulations to Decrypt the Molecular Mechanism of Splicing Modulators 83
An omics perspective to the molecular mechanisms of anticancer metallo-drugs in the computational microscope era 83
Molecular Basis of SARS-CoV-2 Nsp1-Induced Immune Translational Shutdown as Revealed by All-Atom Simulations 82
Recent advances in computational design of potent aromatase inhibitors: open-eye on endocrine-resistant breast cancers 76
Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment 68
Role of computational and structural biology in the development of small-molecule modulators of the spliceosome 66
Targeting Orthosteric and Allosteric Pockets of Aromatase via Dual-Mode Novel Azole Inhibitors 66
The avidin-theophylline complex: A structural and computational study 62
Post-Translational Regulation of CYP450s Metabolism As Revealed by All-Atoms Simulations of the Aromatase Enzyme 62
Molecular Mechanisms of the Blockage of Glioblastoma Motility 60
Molecular basis for endocrine disruption by pesticides targeting aromatase and estrogen receptor 56
Investigating the molecular mechanism of h3b‐8800: A splicing modulator inducing preferential lethality in spliceosome‐mutant cancers 54
Single-digit nanomolar inhibitors lock the aromatase active site via a dualsteric targeting strategy 54
Structural, Thermodynamic, and Kinetic Traits of Antiestrogen-Compounds Selectively Targeting the Y537S Mutant Estrogen Receptor α Transcriptional Activity in Breast Cancer Cell Lines 53
Rational design of allosteric modulators of the aromatase enzyme: An unprecedented therapeutic strategy to fight breast cancer 50
Self-assembling Depsipeptides on Aggregation-Induced Emission Luminogens: A New Way to Create Programmable Nanovesicles and Soft Nanocarriers 48
Totale 9.898
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Categoria #
all - tutte 37.044
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37.044
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202174 0 0 0 0 0 0 0 0 0 0 33 41
2021/2022783 33 87 31 17 6 26 17 221 49 90 68 138
2022/2023821 79 179 11 60 72 144 15 59 106 8 57 31
2023/2024446 32 50 45 31 31 61 70 17 3 3 25 78
2024/20251.560 78 209 110 106 53 38 131 96 110 123 166 340
2025/20263.976 309 189 324 435 394 500 558 463 316 293 195 0
Totale 9.898