SPINELLO, Angelo
SPINELLO, Angelo
Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche
(Dipyrido[3,2-a:2',3'-c]phenazine)(glycinato)copper(II) perchlorate: A novel DNA-intercalator with anti-proliferative activity against thyroid cancer cell lines
2012-01-01 Terenzi, A; Tomasello, L; Spinello, A; Bruno, G; Giordano, C; Barone, G
A Computational Assay of Estrogen Receptor α Antagonists Reveals the Key Common Structural Traits of Drugs Effectively Fighting Refractory Breast Cancers
2018-12-01 Pavlin M.; Spinello A.; Pennati M.; Zaffaroni N.; Gobbi S.; Bisi A.; Colombo G.; Magistrato A.
A Dehydrogenase Dual Hydrogen Abstraction Mechanism Promotes Estrogen Biosynthesis: Can We Expand the Functional Annotation of the Aromatase Enzyme?
2018-07-25 Spinello A.; Pavlin M.; Casalino L.; Magistrato A.
A Novel Peptide with Antifungal Activity from Red Swamp Crayfish Procambarus clarkii
2022-12-10 Punginelli, Diletta; Catania, Valentina; Vazzana, Mirella; Mauro, Manuela; Spinello, Angelo; Barone, Giampaolo; Barberi, Giuseppe; Fiorica, Calogero; Vitale, Maria; Cunsolo, Vincenzo; Saletti, Rosaria; Di Francesco, Antonella; Arizza, Vincenzo; Schillaci, Domenico
A peptide from human β thymosin as a platform for the development of new anti-biofilm agents for Staphylococcus spp. and Pseudomonas aeruginosa
2016-01-01 Schillaci, D; Spinello, A; Cusimano, M.G; Cascioferro, S; Barone, G; Vitale, M; Arizza, V
A Synthetic Derivative of Antimicrobial Peptide Holothuroidin 2 from Mediterranean Sea Cucumber (Holothuria tubulosa) in the Control of Listeria monocytogenes
2019-03-08 Cusimano, Maria Grazia; Spinello, Angelo; Barone, Giampaolo; Schillaci, Domenico; Cascioferro, Stella; Magistrato, Alessandra; Parrino, Barbara; Arizza, Vincenzo; Vitale, Maria
A Theoretical and Experimental Investigation of the Spectroscopic Properties of a DNA-Intercalator Salphen-Type ZnIIComplex
2014-01-01 Biancardi, A; Burgalassi, A; Terenzi, A; Spinello, A; Barone, G; Biver, T; Mennucci, B
All-Atom simulations disclose how cytochrome reductase reshapes the substrate access/egress routes of its partner cyp450s
2020-01-27 Ritacco I.; Saltalamacchia A.; Spinello A.; Ippoliti E.; Magistrato A.
All-atom simulations disentangle the functional dynamics underlying gene maturation in the intron lariat spliceosome
2018-06-26 Casalino L.; Palermo G.; Spinello A.; Rothlisberger U.; Magistrato A.
All-atom simulations to studying metallodrugs/target interactions
2021-04-01 Janos P.; Spinello A.; Magistrato A.
Allosteric Cross-Talk among Spike’s Receptor-Binding Domain Mutations of the SARS-CoV-2 South African Variant Triggers an Effective Hijacking of Human Cell Receptor
2021-06-23 Spinello A.; Saltalamacchia A.; Borisek J.; Magistrato A.
An omics perspective to the molecular mechanisms of anticancer metallo-drugs in the computational microscope era
2017-08-01 Spinello A.; Magistrato A.
Anticancer Activity, Reduction Mechanism and G-Quadruplex DNA Binding of a Redox-Activated Platinum(IV)–Salphen Complex
2022-12-08 Vigna, Vincenzo; Scoditti, Stefano; Spinello, Angelo; Mazzone, Gloria; Sicilia, Emilia
Antimicrobial and Antibiofilm Activity of a Recombinant Fragment of β-Thymosin of Sea Urchin Paracentrotus lividus
2018-10-02 Spinello, Angelo; Cusimano, Maria Grazia; Schillaci, Domenico; Inguglia, Luigi; Barone, Giampaolo; Arizza, Vincenzo
Balanced dual acting compounds targeting aromatase and estrogen receptor α as an emerging therapeutic opportunity to counteract estrogen responsive breast cancer
2021-11-15 Caciolla J.; Martini S.; Spinello A.; Pavlin M.; Turrini E.; Simonelli F.; Belluti F.; Rampa A.; Bisi A.; Fimognari C.; Zaffaroni N.; Gobbi S.; Magistrato A.
Can multiscale simulations unravel the function of metallo-enzymes to improve knowledge-based drug discovery?
2019-04-01 Sgrignani J.; Casalino L.; Doro F.; Spinello A.; Magistrato A.
Circular Dichroism of DNA G-Quadruplexes: Combining Modeling and Spectroscopy to Unravel Complex Structures
2016-01-01 Gattuso, H.; Spinello, A.; Terenzi, A.; Assfeld, X.; Barone, G.; Monari, A.
Computing Metal-Binding Proteins for Therapeutic Benefit
2021-07-06 Spinello A.; Borisek J.; Pavlin M.; Janos P.; Magistrato A.
DNA-Binding and Anticancer Activity of Pyrene-Imidazolium Derivatives
2016-01-01 Bonsignore, 1.; Notaro, A.; Salvo, A.; Spinello, A.; Fiasconaro, G.; Terenzi, A.; Giacalone, F.; Keppler, B.; Giuliano, M.; Gruttadauria, M.; Barone, G.
DNA-Binding of NiII, CuII and ZnII Complexes of Salen Derivatives
2014-01-01 Terenzi, A; Bonsignore, R; Spinello, A; Almerico, AM; Lauria, A; Barone, G