PERRIERA, Riccardo
PERRIERA, Riccardo
Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche
Inhibition of FTSJ1, a tryptophan tRNA-specific 2’-O-methyltransferase as possible mechanism to readthrough premature termination codons (UGAs) of the CFTR mRNA
2022-09-01 Pietro Salvatore Carollo; Marco Tutone; Riccardo Perriera; Rossella Rizzo; Federica Corrao; Ivana Pibiri; Aldo Di Leonardo; Maria Grazia Zizzo; Andrea Pace; Laura Lentini
Nonsense codons suppression. An acute toxicity study of three optimized TRIDs in murine model, safety and tolerability evaluation
2022-12-01 Corrao, Federica; Zizzo, Maria Grazia; Tutone, Marco; Melfi, Raffaella; Fiduccia, Ignazio; Carollo, Pietro Salvatore; Leonardo, Aldo Di; Caldara, Gaetano; Perriera, Riccardo; Pace, Andrea; Belmonte, Beatrice; Sammataro, Selene; Pibiri, Ivana; Lentini, Laura
P015 Translational readthrough inducing drugs: a study of toxicity in mice models and in vitro safety validation of the specific readthrough process.
2022-06-08 Federica Corrao, Riccardo Perriera, Laura Lentini, Maria Grazia Zizzo, Raffaella Melfi, Pietro Salvatore Carollo, Ignazio Fiduccia, Andrea Pace, Marco Tutone, Aldo Di Leonardo, Ivana Pibiri.
Pharmacophore-Based Design of New Chemical Scaffolds as Translational Readthrough-Inducing Drugs (TRIDs)
2020-01-01 Tutone M.; Pibiri I.; Perriera R.; Campofelice A.; Culletta G.; Melfi R.; Pace A.; Almerico A.M.; Lentini L.
Promoting readthrough of nonsense mutations in CF mouse model: Biodistribution and efficacy of NV848 in rescuing CFTR protein expression
2024-01-01 Fiduccia I.; Corrao F.; Zizzo M.G.; Perriera R.; Genovese F.; Vitale E.; Ricci D.; Melfi R.; Tutone M.; Pace A.; Lentini L.; Pibiri I.
Readthrough Approach Using NV Translational Readthrough-Inducing Drugs (TRIDs): A Study of the Possible Off-Target Effects on Natural Termination Codons (NTCs) on TP53 and Housekeeping Gene Expression
2023-10-11 Perriera, Riccardo; Vitale, Emanuele; Pibiri, Ivana; Carollo, Pietro Salvatore; Ricci, Davide; Corrao, Federica; Fiduccia, Ignazio; Melfi, Raffaella; Zizzo, Maria Grazia; Tutone, Marco; Pace, Andrea; Lentini, Laura
Readthrough Inducing Drugs (TRIDs) in human fibroblasts harboring the c.5047 C>T (R1683*) nonsense mutation
2022-09-01 Federica Corrao, Raffaella Melfi, Marco Tutone, Ignazio Fiduccia, Riccardo Perriera, Pietro Salvatore Carollo, Emanuele Vitale, Andrea Pace, Laura Lentini, A. Colige, P. Delvenne, B. Grimbacher, M. Moutschen, I. Pibiri
RESCUE OF LRBA GENE EXPRESSION IN PRIMARY HUMAN FIBROBLASTS CHARACTERISED BY NONSENSE MUTATION c. 5047 (C>T).
2021-04-22 Riccardo PERRIERA, Federica CORRAO, Ivana PIBIRI, Andrea PACE, Laura LENTINI
STUDY OF SMALL MOLECULES IN THE FIGHT AGAINST NONSENSE AND SPLICING MUTATIONS THAT CAUSE CYSTIC FIBROSIS.
2023-06-30
The innovative role of the readthrough inducing drugs in the translation rescue of mRNAs characterized by premature stop codon (PTCs).
Translational Readthrough Inducing Drugs (TRIDs): a study of biodistribution evaluation in mice models
I. Fiduccia, F. Corrao, R. Perriera, A. Di Leonardo, R. Melfi, A. Pace, M. Tutone, M.G. Zizzo, L. Lentini, I. Pibiri