FIDUCCIA, IGNAZIO
FIDUCCIA, IGNAZIO
Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche
A study on molecules promoting the readthrough of nonsense mutations (TRIDs)
2024-12-18
Investigating the inhibition of FTSJ1 a tryptophan tRNA-specific 2’-O-methyltransferase by NV TRIDs, as a mechanism of readthrough in nonsense mutated CFTR
2023-06-01 Pietro Salvatore Carollo; Marco Tutone; Giulia Culletta; Ignazio Fiduccia; Federica Corrao; Ivana Pibiri; Maria Grazia Zizzo; Raffaella Melfi; Andrea Pace; Anna Maria Almerico; Laura Lentini
Nonsense codons suppression. An acute toxicity study of three optimized TRIDs in murine model, safety and tolerability evaluation
2022-12-01 Corrao, Federica; Zizzo, Maria Grazia; Tutone, Marco; Melfi, Raffaella; Fiduccia, Ignazio; Carollo, Pietro Salvatore; Leonardo, Aldo Di; Caldara, Gaetano; Perriera, Riccardo; Pace, Andrea; Belmonte, Beatrice; Sammataro, Selene; Pibiri, Ivana; Lentini, Laura
P015 Translational readthrough inducing drugs: a study of toxicity in mice models and in vitro safety validation of the specific readthrough process.
2022-06-08 Federica Corrao, Riccardo Perriera, Laura Lentini, Maria Grazia Zizzo, Raffaella Melfi, Pietro Salvatore Carollo, Ignazio Fiduccia, Andrea Pace, Marco Tutone, Aldo Di Leonardo, Ivana Pibiri.
Promoting readthrough of nonsense mutations in CF mouse model: Biodistribution and efficacy of NV848 in rescuing CFTR protein expression
2024-01-01 Fiduccia I.; Corrao F.; Zizzo M.G.; Perriera R.; Genovese F.; Vitale E.; Ricci D.; Melfi R.; Tutone M.; Pace A.; Lentini L.; Pibiri I.
Readthrough Approach Using NV Translational Readthrough-Inducing Drugs (TRIDs): A Study of the Possible Off-Target Effects on Natural Termination Codons (NTCs) on TP53 and Housekeeping Gene Expression
2023-10-11 Perriera, Riccardo; Vitale, Emanuele; Pibiri, Ivana; Carollo, Pietro Salvatore; Ricci, Davide; Corrao, Federica; Fiduccia, Ignazio; Melfi, Raffaella; Zizzo, Maria Grazia; Tutone, Marco; Pace, Andrea; Lentini, Laura
Readthrough Inducing Drugs (TRIDs) in human fibroblasts harboring the c.5047 C>T (R1683*) nonsense mutation
2022-09-01 Federica Corrao, Raffaella Melfi, Marco Tutone, Ignazio Fiduccia, Riccardo Perriera, Pietro Salvatore Carollo, Emanuele Vitale, Andrea Pace, Laura Lentini, A. Colige, P. Delvenne, B. Grimbacher, M. Moutschen, I. Pibiri
Shaping 1,2,4-Triazolium Fluorinated Ionic Liquid Crystals
2023-02-24 Rizzo C.; Fiduccia I.; Buscemi S.; Palumbo Piccionello A.; Pace A.; Pibiri I.
Translational Readthrough Inducing Drugs (TRIDs): a study of biodistribution evaluation in mice models
I. Fiduccia, F. Corrao, R. Perriera, A. Di Leonardo, R. Melfi, A. Pace, M. Tutone, M.G. Zizzo, L. Lentini, I. Pibiri
Unlocking Cellular Secrets: Charting Proteomic Frontiers in LRBA Deficiency Through the Lens of Readthrough Promoters
I. Fiduccia, D. Ricci, F. Corrao, E. Vitale, R. Melfi, A. Pace, M. Tutone, M.G. Zizzo, L. Lentini, I. Pibiri, Michel Moutschen, Samuel Meier-Menches