Archivio istituzionale della ricerca dell'Università degli Studi di Palermo

LENTINI, Laura
 Distribuzione geografica
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Continente #
NA - Nord America 7.995
EU - Europa 6.472
AS - Asia 4.820
SA - Sud America 668
AF - Africa 177
Continente sconosciuto - Info sul continente non disponibili 20
OC - Oceania 13
Totale 20.165
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Nazione #
US - Stati Uniti d'America 7.848
IT - Italia 1.914
SG - Singapore 1.701
RU - Federazione Russa 1.506
CN - Cina 1.247
DE - Germania 560
BR - Brasile 514
FI - Finlandia 485
VN - Vietnam 480
HK - Hong Kong 439
UA - Ucraina 417
PL - Polonia 309
FR - Francia 288
GB - Regno Unito 254
JP - Giappone 237
IN - India 222
IE - Irlanda 197
SE - Svezia 154
NL - Olanda 109
CA - Canada 80
KR - Corea 75
TR - Turchia 64
ES - Italia 63
CI - Costa d'Avorio 60
AR - Argentina 56
BD - Bangladesh 54
AT - Austria 48
IQ - Iraq 45
MX - Messico 44
BE - Belgio 41
IL - Israele 35
CH - Svizzera 26
ID - Indonesia 26
ZA - Sudafrica 25
RO - Romania 24
IR - Iran 22
UZ - Uzbekistan 22
PT - Portogallo 20
EC - Ecuador 19
CL - Cile 18
PK - Pakistan 18
VE - Venezuela 18
MY - Malesia 17
XK - ???statistics.table.value.countryCode.XK??? 17
SA - Arabia Saudita 16
MA - Marocco 15
PY - Paraguay 15
CO - Colombia 14
DZ - Algeria 13
EG - Egitto 13
NG - Nigeria 13
KE - Kenya 12
AU - Australia 11
PH - Filippine 11
CZ - Repubblica Ceca 9
JO - Giordania 9
TN - Tunisia 9
AZ - Azerbaigian 8
GR - Grecia 8
TW - Taiwan 8
AE - Emirati Arabi Uniti 7
JM - Giamaica 7
LT - Lituania 7
KZ - Kazakistan 6
LB - Libano 6
QA - Qatar 6
RS - Serbia 6
UY - Uruguay 6
BG - Bulgaria 5
BO - Bolivia 5
ET - Etiopia 5
NP - Nepal 5
SY - Repubblica araba siriana 5
DK - Danimarca 4
GE - Georgia 4
HN - Honduras 4
NO - Norvegia 4
TH - Thailandia 4
AL - Albania 3
BY - Bielorussia 3
CR - Costa Rica 3
CY - Cipro 3
KH - Cambogia 3
KW - Kuwait 3
PE - Perù 3
PS - Palestinian Territory 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BH - Bahrain 2
HU - Ungheria 2
KG - Kirghizistan 2
MD - Moldavia 2
NE - Niger 2
NZ - Nuova Zelanda 2
OM - Oman 2
PA - Panama 2
SK - Slovacchia (Repubblica Slovacca) 2
TZ - Tanzania 2
AM - Armenia 1
AO - Angola 1
BB - Barbados 1
Totale 20.147
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Città #
Singapore 1.233
Ashburn 1.000
Palermo 667
Fairfield 613
San Jose 585
Chandler 430
Hong Kong 422
Ann Arbor 357
Houston 344
Woodbridge 331
Wilmington 294
Zgierz 259
Moscow 248
Jacksonville 222
Seattle 207
Dublin 196
Cambridge 191
Beijing 188
Tokyo 171
Council Bluffs 166
Medford 156
Ho Chi Minh City 143
Los Angeles 142
Dallas 126
New York 123
Des Moines 122
Hanoi 122
Santa Clara 119
Helsinki 118
Lauterbourg 115
Nanjing 107
Princeton 100
Bremen 96
Frankfurt am Main 95
Hyderabad 95
Rome 95
Hefei 94
The Dalles 83
Milan 76
Buffalo 73
Boardman 68
Philadelphia 65
Abidjan 60
Tulsa 58
São Paulo 52
San Diego 46
Altamura 45
Dearborn 44
Shenyang 43
Orem 42
Amsterdam 39
Changsha 39
Jinan 39
Lawrence 37
Tianjin 36
Brussels 34
Ludwigshafen am Rhein 34
Guangzhou 33
London 33
Paris 32
Phoenix 31
Warsaw 31
Düsseldorf 30
Hebei 30
Montreal 30
Barcelona 28
Chicago 28
Munich 27
Nanchang 27
Jiaxing 26
Da Nang 25
Izmir 25
Ningbo 25
Chennai 24
Haiphong 24
Redwood City 24
Catania 22
Tel Aviv 22
Vienna 22
Brooklyn 21
Columbus 21
Naples 21
Venice 21
Manassas 20
Verona 20
Atlanta 19
Birmingham 18
Partanna 17
Chikmagalūr 16
Johannesburg 16
Mumbai 16
Seongnam 16
Berlin 15
Boston 15
Denver 15
Nuremberg 15
Poplar 15
Taizhou 15
Tashkent 15
Zhengzhou 15
Totale 12.066
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Nome #
Deciphering the Nonsense Readthrough Mechanism of Action of Ataluren: An in Silico Compared Study 318
COMBINING TRANSLATION READTHROUGH INDUCING DRUGS AND NONSENSE MEDIATED DECAY PATWHAY INHIBITION TO THE CFTR RESCUE IN CYSTIC FIBROSIS CELL MODEL SYSTEM 288
Inhibition of FTSJ1, a tryptophan tRNA-specific 2’-O-methyltransferase as possible mechanism to readthrough premature termination codons (UGAs) of the CFTR mRNA 287
P015 Translational readthrough inducing drugs: a study of toxicity in mice models and in vitro safety validation of the specific readthrough process. 279
Enhancement of premature stop codon readthrough in the CFTR gene by Ataluren (PTC124) derivatives 277
Caffeine boosts Ataluren's readthrough activity 277
Bypass of cell cycle arrest induced by transient DNMT1 post-transcriptional silencing triggers aneuploidy in human cells 260
CENPA overexpression promotes genome instability in pRb-depleted human cells. 250
Toward a Rationale for the PTC124 (Ataluren) Promoted Readthrough of Premature Stop Codons: A Computational Approach and GFP-Reporter Cell-Based Assay 246
Retinoblastoma epidemiology: Does the evidence matter? 240
Aurora-A transcriptional silencing and Vincristine treatment show a synergistic effect in human tumor cells 233
AZIONE READTHROUGH DI DERIVATI DEL PTC124 SU SISTEMI MODELLO CELLULARI E IN CELLULE DI EPITELIO BRONCHIALE-FC IB3.1 (CFTR F508/W1282X ) 231
Adenosine negatively regulates duodenal motility in mice: role of A1 and A2a receptors . 230
Uno studio comparativo in silico sui possibili target di Ataluren e analoghi farmaci promotori di readthrough di codoni di stop prematuri 228
Simultaneous Aurora-A/STK15 overexpression and centrosome amplification induce chromosomal instability in tumour cells with a MIN phenotype 224
p14(ARF) Prevents Proliferation of Aneuploid Cells by Inducing p53-Dependent Apoptosis 221
Derivati Ossadiazolici per il trattamento della fibrosi cistica: Readthrough di mutazioni nonsense 218
DNA demethylation caused By 5-Aza-2'-Deoxycytidine induces mitotic alterations and aneuploidy 212
DNMT1 depletion activates a pathway p14ARF/TP53 controlled that induces G1 arrest preventing DNA demethylation and aneuploidy 210
Centrosome amplification induced by hydroxyurea leads to aneuploidy in pRB deficient human and mouse fibroblasts 208
Exploring the readthrough of nonsense mutations by non-acidic Ataluren analogues selected by ligand-based virtual screening 197
Strategies against nonsense: oxadiazoles as translational readthrough-inducing drugs (TRIDs) 197
Pharmacophore-Based Design of New Chemical Scaffolds as Translational Readthrough-Inducing Drugs (TRIDs) 197
Glucagon-like peptide-1 relaxes gastric antrum through nitric oxide in mice. 195
Rescuing the CFTR protein function: Introducing 1,3,4-oxadiazoles as translational readthrough inducing drugs 193
Identification of pathways involved in aneuploidy onset and its tolerance using a DNA microarray approach 192
RNAi mediated acute depletion of Retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation 186
Premature termination codon 124 derivatives as a novel approach to improve the read-through of premature amber and ochre stop codons 186
RESTORING MMACHC EXPRESSION: TRIDs AS A PROMISING APPROACH FOR cblC DEFICIENCY TREATMENT 185
Translational Readthrough Inducing Drugs (TRIDs): a study of biodistribution evaluation in mice models 183
Gastric relaxation induced by glucagon-like peptide-2 in mice fed a high-fat diet or fasted. 183
A1 ADENOSINE RECEPTOR MODULATION OF CONTRACTILITY IN MOUSE DUODENUM LONGITUDINAL MUSCLE 182
MAD2 depletion triggers premature cellular senescence in human primary fibroblasts by activating a P53 pathway preventing aneuploid cells propagation. 179
Glucagon-like peptide-2 analog and inflammatory state in obese mice 179
AN APPROACH AGAINST CANCER: TRANSLATIONAL READTHROUGH INDUCING DRUGS (TRIDs) FOR RESTORING P53 EXPRESSION IN STOP MUTATED CELLS 178
NEW TRANSLATIONAL READTHROUGH INDUCING DRUGS RESCUING NONSENSE MUTATED TP53: STRATEGIES AGAINST CANCER 178
Perfluorocarbons-graphene oxide nanoplatforms as biocompatible oxygen reservoirs 178
Acute loss of pRB function induces centrosome amplification and aneuploidy both in murine and human fibroblasts 177
Simultaneous reduction of MAD2 and BUBR1 expression induces mitotic spindle alterations associated with p53 dependent cell cycle arrest and death 177
Targeting nonsense: Optimization of 1,2,4-oxadiazole trids to rescue cftr expression and functionality in cystic fibrosis cell model systems 177
Preventive Impact of Long-Term Ingestion of Chestnut Honey on Glucose Disorders and Neurodegeneration in Obese Mice 176
EFFECTS OF PLK1 DEPLETION IN CENTROSOME DUPLICATIONS AND CELL CYCLEPROGRESSION IN HCT116 TUMOR CELLS. 175
Acute loss of retinoblastoma function induces centrosomes amplification both in murine and human fibroblasts 175
Aurora-A/STK15 transcriptional silencing and Vincristine treatment show a synergistic effect in human tumour cells 175
Nonsense codons suppression. An acute toxicity study of three optimized TRIDs in murine model, safety and tolerability evaluation 174
RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts 174
Potential translational readthough inducin drugs: an optimized design and synthesis of new chemical scaffolds 172
Investigating REPAIRv2 as a Tool to Edit CFTR mRNA with Premature Stop Codons 172
Low doses of Hydroxyurea induce centrosome amplification and aneuploidy in primary human fibroblasts in culture 170
Aurora A overexpression leads centrosome amplification and aneuploidy in human colon cancer cells with MIN phenotype 169
Bypass of G1 arrest induced by DNMT1 posttranscriptional silencing triggers aneuploidy in human cells. 168
Optimization of a new lead promoting the readthrough of the nonsense mutations for CFTR rescue in human CF cells 167
Acute loss of retinoblastoma function induces centrosome amplification and aneuploidy both in human and murine primary fibroblasts 164
Functional inactivation of pRB results in aneuploid mammalian cells after release from a mitotic block 164
Rescuing nonsense in cancer: recovering p53 tumor suppressor gene expression by translational readthrough inducing drugs (TRIDs) 163
Investigating the inhibition of FTSJ1 a tryptophan tRNA-specific 2’-O-methyltransferase by NV TRIDs, as a mechanism of readthrough in nonsense mutated CFTR 163
Readthrough Inducing Drugs (TRIDs) in human fibroblasts harboring the c.5047 C>T (R1683*) nonsense mutation 163
Promoting readthrough of nonsense mutations in CF mouse model: Biodistribution and efficacy of NV848 in rescuing CFTR protein expression 161
Micronuclei generation and chromosomal instability after RB interferences in human fibroblasts 157
DNA Methyltransferase1 post-transcriptional silencing induces aneuploidy and cell cycle arrest in human cells. 157
RESCUE OF LRBA GENE EXPRESSION IN PRIMARY HUMAN FIBROBLASTS CHARACTERISED BY NONSENSE MUTATION c. 5047 (C>T). 157
PERSONALIZED MEDICINE FIGHTING NONSENSE DISEASES: EXPLORATION OF NV MOLECULES MECHANISM OF ACTION IN PURE-LITE SYSTEM AND THEIR READTHROUGH ACTIVITY IN CHOROIDEREMIA NONSENSE MODEL 156
Design of small molecules and identification of putative anticancer therapeutic targets via in silico tools 155
PTC124 derivatives as a novel approach to improve the readthrough of premature stop codons in the CFTR gene. 153
Does the evidence matter in medicine? The retinoblastoma paradigm. 152
ADENOSINE IS A MODULATOR OF THE CONTRACTILITY OF THE DUODENAL LONGITUDINAL MUSCLE IN MICE 152
RESCUING P53 BY NEW TRANSLATIONAL READTHROUGH INDUCING DRUGS 151
Chromosomal instability promoted by RB depletion relied neither on p53 nor SAC dysfunction in HCT116 tumor cells 148
Gastric relaxation induced by glucagon-like peptide-2 and receptorial expression in fasted or high-fat diet fed mice. 148
AURKA (aurora kinase A) 145
Valutazione dell'azione readthorough della molecola PTC124 su sistemi modello cellulari contenenti mutazioni non senso e in cellule epiteliali bronchiali IB3.1 (delF508/W1282X) derivate da pazienti affetti da fibrosi cistica. 145
FTSJ1 INHIBITION AS A STRATEGY FOR NONSENSE MUTATION SUPPRESSION IN TP53: INTEGRATIVE COMPUTATIONAL AND EXPERIMENTAL ANALYSIS 144
Identification and validation of novel molecules obtained by integrated computational and experimental approaches for the read-through of PTCs in CF cells 144
TRPM8 channel activation reduces the spontaneous contractions in human distal colon 144
Silencing of serine threonine kinase Aurora-2 gene cause G2/M arrest and apotosis in human carcinoma lung large cells 143
Aneuploidy induced by MAD2 haploinsufficiency triggers premature senescence in human primary fibroblast 143
Unlocking Cellular Secrets: Charting Proteomic Frontiers in LRBA Deficiency Through the Lens of Readthrough Promoters 141
Identification of New Translational Readthrough Inducing Drugs 140
Hydroxyurea induces centrosome amplification and slowing down of cell cycle in colo-cancer cells SW480 140
Effetti del Silenziamento dei geni Plk1, Brca1 e Rb nella duplicazione dei centrosomi in cellule tumorali HCT116 140
Evidence for region-specific effects of glucagone-like peptide-2 in mouse stomach 139
Hydroxiurea induces centrosome amplification and slowing down of cell cycle in colo-cancer cells SW480 138
Rescuing CFTR Protein Function: 1,3,4-oxadiazoles versus 1,2,4-oxadiazoles as readthrough inducing drugs 138
Silencing of serine threonine kinase Aurora-2 gene causes G2/M arrest and apoptosis in human carcinoma lung large cells. 137
CFTR G542X/ G542X mouse model carrying nonsense mutations, useful tool to test the efficacy of translational readthrough-based therapy in Cystic Fibrosis 135
Does GLP-2 receptor expression change dynamically in fed and fasted states? 135
TRIDs therapy for restoring p53 expression on stop mutated cells 133
Inhalable nano into micro dry powders for ivacaftor delivery: the role of mannitol and cysteamine as mucus-active agents 133
PTC124 DERIVATIVES AS A NOVEL APPROACH TO IMPROVE THE READTHROUGH OF PREMATURE AMBER AND OCHRE STOP CODONS 129
Aging modifies receptor expression but not muscular contractile response to angiotensin II in rat jejunum 129
A precision medicine approach to primary immunodeficiency disease: Ataluren strikes nonsense mutations once again 127
Identification of a new molecule with readthrough activity to rescue CFTR protein function 127
A new approach against cancer: translational readthrough inducing drugs rescuing nonsense mutated TP53 126
Sensitizing tumor cells via rescue of nonsense driver mutations: a promising therapeutic strategy 125
Transient silencing of MAD2 induces mitotic abnormalities and p21waf1 overexpression in primary human fibroblasts 125
RB acute loss affects expression of mitotic genes and is associated with centrosome amplification and aneuploidy 124
X CONVENTION OF INVESTIGATORS IN CYSTIC FIBROSIS 124
DNMT1 transient silencing induces aneuploidy, premature separated chromatids and centromeric chromatin alterations 122
Identification of mechanism(s) leading to hyperdiploidy in progenitor tumor cells derived from MCF7 breast cancer cells 122
Identification and validation of novel molecules obtained by integrated computational and experimental approaches for the readthrough of PTCs in CF cells 122
Totale 17.526
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Categoria #
all - tutte 63.240
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 63.240
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021294 0 0 0 0 0 0 0 0 0 0 135 159
2021/20221.230 80 291 29 24 30 40 37 78 148 167 67 239
2022/20231.741 164 171 54 317 174 272 130 99 172 46 85 57
2023/20241.086 73 125 53 99 85 160 107 161 5 34 18 166
2024/20252.739 98 149 136 178 134 163 141 242 150 401 344 603
2025/20268.781 579 228 538 890 956 1.270 1.332 998 728 953 309 0
Totale 20.837