Archivio istituzionale della ricerca dell'Università degli Studi di Palermo

LENTINI, Laura
 Distribuzione geografica
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Continente #
NA - Nord America 8.927
EU - Europa 6.663
AS - Asia 4.975
Continente sconosciuto - Info sul continente non disponibili 699
SA - Sud America 694
AF - Africa 177
OC - Oceania 22
Totale 22.157
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Nazione #
US - Stati Uniti d'America 8.691
IT - Italia 2.062
SG - Singapore 1.708
RU - Federazione Russa 1.506
CN - Cina 1.251
DE - Germania 560
BR - Brasile 520
FI - Finlandia 485
VN - Vietnam 485
HK - Hong Kong 446
UA - Ucraina 417
PL - Polonia 312
FR - Francia 302
GB - Regno Unito 254
JP - Giappone 239
IN - India 228
IE - Irlanda 197
BD - Bangladesh 170
SE - Svezia 169
CA - Canada 118
NL - Olanda 113
KR - Corea 75
ES - Italia 66
TR - Turchia 65
CI - Costa d'Avorio 60
AR - Argentina 59
MX - Messico 52
AT - Austria 48
IQ - Iraq 45
BE - Belgio 41
IL - Israele 35
ID - Indonesia 27
CH - Svizzera 26
ZA - Sudafrica 25
RO - Romania 24
EC - Ecuador 23
IR - Iran 22
UZ - Uzbekistan 22
VE - Venezuela 22
PT - Portogallo 21
AU - Australia 20
CO - Colombia 20
MY - Malesia 19
CL - Cile 18
PK - Pakistan 18
PY - Paraguay 17
XK - ???statistics.table.value.countryCode.XK??? 17
JM - Giamaica 16
SA - Arabia Saudita 16
MA - Marocco 15
DZ - Algeria 13
EG - Egitto 13
NG - Nigeria 13
KE - Kenya 12
PH - Filippine 12
CR - Costa Rica 11
CZ - Repubblica Ceca 11
JO - Giordania 9
SV - El Salvador 9
TN - Tunisia 9
AZ - Azerbaigian 8
GR - Grecia 8
HN - Honduras 8
QA - Qatar 8
TW - Taiwan 8
AE - Emirati Arabi Uniti 7
LT - Lituania 7
KZ - Kazakistan 6
LB - Libano 6
RS - Serbia 6
UY - Uruguay 6
BG - Bulgaria 5
BO - Bolivia 5
ET - Etiopia 5
NP - Nepal 5
SY - Repubblica araba siriana 5
DK - Danimarca 4
GE - Georgia 4
NI - Nicaragua 4
NO - Norvegia 4
PE - Perù 4
TH - Thailandia 4
AL - Albania 3
BY - Bielorussia 3
CY - Cipro 3
KH - Cambogia 3
KW - Kuwait 3
MD - Moldavia 3
PA - Panama 3
PR - Porto Rico 3
PS - Palestinian Territory 3
TT - Trinidad e Tobago 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BB - Barbados 2
BH - Bahrain 2
CW - ???statistics.table.value.countryCode.CW??? 2
DO - Repubblica Dominicana 2
GT - Guatemala 2
HU - Ungheria 2
KG - Kirghizistan 2
Totale 21.452
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Città #
Singapore 1.239
Ashburn 1.058
San Jose 766
Palermo 688
Fairfield 613
Chandler 430
Hong Kong 426
Ann Arbor 357
Houston 348
Woodbridge 332
Wilmington 295
Council Bluffs 259
Zgierz 259
Moscow 248
Jacksonville 224
Seattle 210
Dublin 197
Cambridge 193
Beijing 189
Tokyo 172
Los Angeles 166
Medford 156
Ho Chi Minh City 144
Santa Clara 137
New York 135
Dallas 131
Hanoi 123
Des Moines 122
Helsinki 118
Lauterbourg 115
Nanjing 107
Rome 105
Princeton 100
Bremen 96
Hyderabad 96
Frankfurt am Main 95
Hefei 94
Boardman 91
Milan 88
The Dalles 86
Buffalo 80
Philadelphia 71
Abidjan 60
Tulsa 58
São Paulo 52
San Diego 46
Altamura 45
Dearborn 44
Shenyang 43
Orem 42
Changsha 41
Amsterdam 39
Jinan 39
Phoenix 38
Chicago 37
Lawrence 37
Tianjin 36
Brussels 34
Ludwigshafen am Rhein 34
Montreal 34
Guangzhou 33
London 33
Paris 32
Warsaw 31
Düsseldorf 30
Hebei 30
Barcelona 28
Naples 28
Munich 27
Nanchang 27
Jiaxing 26
Toronto 26
Da Nang 25
Haiphong 25
Izmir 25
Ningbo 25
Brooklyn 24
Chennai 24
Redwood City 24
Catania 22
Columbus 22
Tel Aviv 22
Vienna 22
Venice 21
Atlanta 20
Manassas 20
Mumbai 20
Verona 20
Birmingham 19
Partanna 17
Boston 16
Chikmagalūr 16
Denver 16
Johannesburg 16
Memphis 16
Mexico City 16
Seongnam 16
Berlin 15
Nuremberg 15
Poplar 15
Totale 12.623
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Nome #
Deciphering the Nonsense Readthrough Mechanism of Action of Ataluren: An in Silico Compared Study 330
COMBINING TRANSLATION READTHROUGH INDUCING DRUGS AND NONSENSE MEDIATED DECAY PATWHAY INHIBITION TO THE CFTR RESCUE IN CYSTIC FIBROSIS CELL MODEL SYSTEM 311
Inhibition of FTSJ1, a tryptophan tRNA-specific 2’-O-methyltransferase as possible mechanism to readthrough premature termination codons (UGAs) of the CFTR mRNA 296
Caffeine boosts Ataluren's readthrough activity 287
P015 Translational readthrough inducing drugs: a study of toxicity in mice models and in vitro safety validation of the specific readthrough process. 287
Enhancement of premature stop codon readthrough in the CFTR gene by Ataluren (PTC124) derivatives 285
Bypass of cell cycle arrest induced by transient DNMT1 post-transcriptional silencing triggers aneuploidy in human cells 264
CENPA overexpression promotes genome instability in pRb-depleted human cells. 257
Toward a Rationale for the PTC124 (Ataluren) Promoted Readthrough of Premature Stop Codons: A Computational Approach and GFP-Reporter Cell-Based Assay 254
Retinoblastoma epidemiology: Does the evidence matter? 245
AZIONE READTHROUGH DI DERIVATI DEL PTC124 SU SISTEMI MODELLO CELLULARI E IN CELLULE DI EPITELIO BRONCHIALE-FC IB3.1 (CFTR F508/W1282X ) 239
Aurora-A transcriptional silencing and Vincristine treatment show a synergistic effect in human tumor cells 236
Adenosine negatively regulates duodenal motility in mice: role of A1 and A2a receptors . 236
Uno studio comparativo in silico sui possibili target di Ataluren e analoghi farmaci promotori di readthrough di codoni di stop prematuri 235
Derivati Ossadiazolici per il trattamento della fibrosi cistica: Readthrough di mutazioni nonsense 232
p14(ARF) Prevents Proliferation of Aneuploid Cells by Inducing p53-Dependent Apoptosis 229
Simultaneous Aurora-A/STK15 overexpression and centrosome amplification induce chromosomal instability in tumour cells with a MIN phenotype 228
DNA demethylation caused By 5-Aza-2'-Deoxycytidine induces mitotic alterations and aneuploidy 218
DNMT1 depletion activates a pathway p14ARF/TP53 controlled that induces G1 arrest preventing DNA demethylation and aneuploidy 215
Centrosome amplification induced by hydroxyurea leads to aneuploidy in pRB deficient human and mouse fibroblasts 214
Glucagon-like peptide-1 relaxes gastric antrum through nitric oxide in mice. 214
Nonsense codons suppression. An acute toxicity study of three optimized TRIDs in murine model, safety and tolerability evaluation 210
Strategies against nonsense: oxadiazoles as translational readthrough-inducing drugs (TRIDs) 208
AN APPROACH AGAINST CANCER: TRANSLATIONAL READTHROUGH INDUCING DRUGS (TRIDs) FOR RESTORING P53 EXPRESSION IN STOP MUTATED CELLS 205
FTSJ1 INHIBITION AS A STRATEGY FOR NONSENSE MUTATION SUPPRESSION IN TP53: INTEGRATIVE COMPUTATIONAL AND EXPERIMENTAL ANALYSIS 204
PERSONALIZED MEDICINE FIGHTING NONSENSE DISEASES: EXPLORATION OF NV MOLECULES MECHANISM OF ACTION IN PURE-LITE SYSTEM AND THEIR READTHROUGH ACTIVITY IN CHOROIDEREMIA NONSENSE MODEL 204
Pharmacophore-Based Design of New Chemical Scaffolds as Translational Readthrough-Inducing Drugs (TRIDs) 204
Exploring the readthrough of nonsense mutations by non-acidic Ataluren analogues selected by ligand-based virtual screening 202
Rescuing the CFTR protein function: Introducing 1,3,4-oxadiazoles as translational readthrough inducing drugs 201
RESTORING MMACHC EXPRESSION: TRIDs AS A PROMISING APPROACH FOR cblC DEFICIENCY TREATMENT 197
Identification of pathways involved in aneuploidy onset and its tolerance using a DNA microarray approach 197
Premature termination codon 124 derivatives as a novel approach to improve the read-through of premature amber and ochre stop codons 195
NEW TRANSLATIONAL READTHROUGH INDUCING DRUGS RESCUING NONSENSE MUTATED TP53: STRATEGIES AGAINST CANCER 193
Glucagon-like peptide-2 analog and inflammatory state in obese mice 192
Translational Readthrough Inducing Drugs (TRIDs): a study of biodistribution evaluation in mice models 190
RNAi mediated acute depletion of Retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation 190
Gastric relaxation induced by glucagon-like peptide-2 in mice fed a high-fat diet or fasted. 189
A1 ADENOSINE RECEPTOR MODULATION OF CONTRACTILITY IN MOUSE DUODENUM LONGITUDINAL MUSCLE 188
Targeting nonsense: Optimization of 1,2,4-oxadiazole trids to rescue cftr expression and functionality in cystic fibrosis cell model systems 186
RESCUE OF LRBA GENE EXPRESSION IN PRIMARY HUMAN FIBROBLASTS CHARACTERISED BY NONSENSE MUTATION c. 5047 (C>T). 185
Aurora-A/STK15 transcriptional silencing and Vincristine treatment show a synergistic effect in human tumour cells 184
MAD2 depletion triggers premature cellular senescence in human primary fibroblasts by activating a P53 pathway preventing aneuploid cells propagation. 184
Promoting readthrough of nonsense mutations in CF mouse model: Biodistribution and efficacy of NV848 in rescuing CFTR protein expression 183
EFFECTS OF PLK1 DEPLETION IN CENTROSOME DUPLICATIONS AND CELL CYCLEPROGRESSION IN HCT116 TUMOR CELLS. 183
Simultaneous reduction of MAD2 and BUBR1 expression induces mitotic spindle alterations associated with p53 dependent cell cycle arrest and death 183
Perfluorocarbons-graphene oxide nanoplatforms as biocompatible oxygen reservoirs 183
Acute loss of retinoblastoma function induces centrosomes amplification both in murine and human fibroblasts 182
Investigating REPAIRv2 as a Tool to Edit CFTR mRNA with Premature Stop Codons 182
Acute loss of pRB function induces centrosome amplification and aneuploidy both in murine and human fibroblasts 181
RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts 181
Preventive Impact of Long-Term Ingestion of Chestnut Honey on Glucose Disorders and Neurodegeneration in Obese Mice 181
Rescuing nonsense in cancer: recovering p53 tumor suppressor gene expression by translational readthrough inducing drugs (TRIDs) 178
Potential translational readthough inducin drugs: an optimized design and synthesis of new chemical scaffolds 178
Low doses of Hydroxyurea induce centrosome amplification and aneuploidy in primary human fibroblasts in culture 178
Optimization of a new lead promoting the readthrough of the nonsense mutations for CFTR rescue in human CF cells 175
Aurora A overexpression leads centrosome amplification and aneuploidy in human colon cancer cells with MIN phenotype 174
Bypass of G1 arrest induced by DNMT1 posttranscriptional silencing triggers aneuploidy in human cells. 172
Readthrough Inducing Drugs (TRIDs) in human fibroblasts harboring the c.5047 C>T (R1683*) nonsense mutation 168
Acute loss of retinoblastoma function induces centrosome amplification and aneuploidy both in human and murine primary fibroblasts 168
Functional inactivation of pRB results in aneuploid mammalian cells after release from a mitotic block 168
Investigating the inhibition of FTSJ1 a tryptophan tRNA-specific 2’-O-methyltransferase by NV TRIDs, as a mechanism of readthrough in nonsense mutated CFTR 166
Design of small molecules and identification of putative anticancer therapeutic targets via in silico tools 164
Micronuclei generation and chromosomal instability after RB interferences in human fibroblasts 164
DNA Methyltransferase1 post-transcriptional silencing induces aneuploidy and cell cycle arrest in human cells. 162
PTC124 derivatives as a novel approach to improve the readthrough of premature stop codons in the CFTR gene. 162
Sensitizing tumor cells via rescue of nonsense driver mutations: a promising therapeutic strategy 161
ADENOSINE IS A MODULATOR OF THE CONTRACTILITY OF THE DUODENAL LONGITUDINAL MUSCLE IN MICE 161
AURKA (aurora kinase A) 159
RESCUING P53 BY NEW TRANSLATIONAL READTHROUGH INDUCING DRUGS 157
Gastric relaxation induced by glucagon-like peptide-2 and receptorial expression in fasted or high-fat diet fed mice. 157
Does the evidence matter in medicine? The retinoblastoma paradigm. 154
Chromosomal instability promoted by RB depletion relied neither on p53 nor SAC dysfunction in HCT116 tumor cells 154
Identification and validation of novel molecules obtained by integrated computational and experimental approaches for the read-through of PTCs in CF cells 154
Rescuing CFTR Protein Function: 1,3,4-oxadiazoles versus 1,2,4-oxadiazoles as readthrough inducing drugs 153
Aneuploidy induced by MAD2 haploinsufficiency triggers premature senescence in human primary fibroblast 151
TRPM8 channel activation reduces the spontaneous contractions in human distal colon 150
Effetti del Silenziamento dei geni Plk1, Brca1 e Rb nella duplicazione dei centrosomi in cellule tumorali HCT116 148
Silencing of serine threonine kinase Aurora-2 gene cause G2/M arrest and apotosis in human carcinoma lung large cells 148
Valutazione dell'azione readthorough della molecola PTC124 su sistemi modello cellulari contenenti mutazioni non senso e in cellule epiteliali bronchiali IB3.1 (delF508/W1282X) derivate da pazienti affetti da fibrosi cistica. 148
Hydroxiurea induces centrosome amplification and slowing down of cell cycle in colo-cancer cells SW480 147
Identification of New Translational Readthrough Inducing Drugs 146
CFTR G542X/ G542X mouse model carrying nonsense mutations, useful tool to test the efficacy of translational readthrough-based therapy in Cystic Fibrosis 145
Hydroxyurea induces centrosome amplification and slowing down of cell cycle in colo-cancer cells SW480 145
Unlocking Cellular Secrets: Charting Proteomic Frontiers in LRBA Deficiency Through the Lens of Readthrough Promoters 143
Evidence for region-specific effects of glucagone-like peptide-2 in mouse stomach 143
Silencing of serine threonine kinase Aurora-2 gene causes G2/M arrest and apoptosis in human carcinoma lung large cells. 143
Missing evidences in cancer genetics: The retinoblastoma paradigm. 143
Inhalable nano into micro dry powders for ivacaftor delivery: the role of mannitol and cysteamine as mucus-active agents 143
TRIDs therapy for restoring p53 expression on stop mutated cells 139
Does GLP-2 receptor expression change dynamically in fed and fasted states? 139
A precision medicine approach to primary immunodeficiency disease: Ataluren strikes nonsense mutations once again 137
Aging modifies receptor expression but not muscular contractile response to angiotensin II in rat jejunum 137
PTC124 DERIVATIVES AS A NOVEL APPROACH TO IMPROVE THE READTHROUGH OF PREMATURE AMBER AND OCHRE STOP CODONS 134
Identification and validation of novel molecules obtained by integrated computational and experimental approaches for the readthrough of PTCs in CF cells 133
Identification of a new molecule with readthrough activity to rescue CFTR protein function 133
Transient silencing of MAD2 induces mitotic abnormalities and p21waf1 overexpression in primary human fibroblasts 132
A new approach against cancer: translational readthrough inducing drugs rescuing nonsense mutated TP53 130
X CONVENTION OF INVESTIGATORS IN CYSTIC FIBROSIS 130
Correcting CFTR mRNA splicing defects with the plant cytokine kinetin and its analogues 128
RB acute loss affects expression of mitotic genes and is associated with centrosome amplification and aneuploidy 128
Totale 18.489
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Categoria #
all - tutte 68.765
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 68.765
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.150 0 291 29 24 30 40 37 78 148 167 67 239
2022/20231.741 164 171 54 317 174 272 130 99 172 46 85 57
2023/20241.086 73 125 53 99 85 160 107 161 5 34 18 166
2024/20252.739 98 149 136 178 134 163 141 242 150 401 344 603
2025/20269.355 579 228 538 890 956 1.270 1.332 998 728 953 428 455
2026/2027746 463 283 0 0 0 0 0 0 0 0 0 0
Totale 22.157