Archivio istituzionale della ricerca dell'Università degli Studi di Palermo

LENTINI, Laura
 Distribuzione geografica
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Continente #
NA - Nord America 5.108
EU - Europa 3.242
AS - Asia 1.215
AF - Africa 65
SA - Sud America 20
Continente sconosciuto - Info sul continente non disponibili 8
OC - Oceania 8
Totale 9.666
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Nazione #
US - Stati Uniti d'America 5.096
IT - Italia 1.300
CN - Cina 557
FI - Finlandia 399
UA - Ucraina 398
SG - Singapore 368
DE - Germania 328
IE - Irlanda 186
GB - Regno Unito 154
SE - Svezia 133
IN - India 128
FR - Francia 74
RU - Federazione Russa 65
CI - Costa d'Avorio 58
JP - Giappone 52
NL - Olanda 49
BE - Belgio 41
TR - Turchia 27
ES - Italia 25
RO - Romania 24
HK - Hong Kong 22
KR - Corea 17
CH - Svizzera 12
IR - Iran 12
PL - Polonia 12
AT - Austria 9
CA - Canada 9
CL - Cile 8
GR - Grecia 7
IL - Israele 7
AU - Australia 6
BR - Brasile 6
PT - Portogallo 6
UZ - Uzbekistan 6
XK - ???statistics.table.value.countryCode.XK??? 5
CO - Colombia 4
DK - Danimarca 4
DZ - Algeria 4
NO - Norvegia 4
TW - Taiwan 4
BG - Bulgaria 3
CZ - Repubblica Ceca 3
MX - Messico 3
QA - Qatar 3
RS - Serbia 3
VN - Vietnam 3
A2 - ???statistics.table.value.countryCode.A2??? 2
LB - Libano 2
MY - Malesia 2
NZ - Nuova Zelanda 2
UY - Uruguay 2
AE - Emirati Arabi Uniti 1
EU - Europa 1
HU - Ungheria 1
ID - Indonesia 1
LK - Sri Lanka 1
MD - Moldavia 1
NG - Nigeria 1
PS - Palestinian Territory 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
TN - Tunisia 1
ZA - Sudafrica 1
Totale 9.666
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Città #
Fairfield 613
Ashburn 448
Palermo 441
Chandler 430
Ann Arbor 357
Woodbridge 331
Houston 327
Singapore 307
Wilmington 293
Jacksonville 222
Seattle 202
Cambridge 191
Dublin 185
Medford 156
Des Moines 112
Nanjing 107
Princeton 99
Bremen 96
Hyderabad 87
Boardman 66
Milan 60
Abidjan 58
Tulsa 58
Helsinki 53
Santa Clara 48
Beijing 46
San Diego 46
Altamura 45
Dearborn 44
Shenyang 43
New York 42
Jinan 39
Lawrence 37
Brussels 34
Ludwigshafen am Rhein 34
Hebei 30
Tianjin 30
Changsha 29
Rome 28
Nanchang 27
Düsseldorf 26
Jiaxing 25
Ningbo 24
Redwood City 24
Philadelphia 23
Izmir 21
Amsterdam 19
London 19
Venice 19
Los Angeles 18
Verona 18
Paris 17
Phoenix 17
Barcelona 16
Chikmagalūr 16
Guangzhou 16
Seongnam 16
Columbus 15
Taizhou 15
Zhengzhou 15
Saint Petersburg 14
Hong Kong 13
Kumar 13
Tokyo 13
Edinburgh 12
Haikou 12
Kunming 11
Volturara Irpina 11
Favara 10
Lanzhou 10
Naples 9
San Paolo di Civitate 9
Sciacca 9
Trapani 9
Apeldoorn 8
Bari 8
Ferrara 8
Washington 8
Bacoli 7
Catania 7
Dallas 7
Turin 7
Baltimore 6
Carini 6
Carovigno 6
Kilburn 6
Moscow 6
Ravenna 6
Taiyuan 6
Berlin 5
Falkenstein 5
Frankfurt 5
Fuzhou 5
Hangzhou 5
Hefei 5
Hoover 5
Liège 5
Marcallo con Casone 5
Norwalk 5
Orange 5
Totale 6.592
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Nome #
Deciphering the Nonsense Readthrough Mechanism of Action of Ataluren: An in Silico Compared Study 266
Caffeine boosts Ataluren's readthrough activity 189
Enhancement of premature stop codon readthrough in the CFTR gene by Ataluren (PTC124) derivatives 187
Toward a Rationale for the PTC124 (Ataluren) Promoted Readthrough of Premature Stop Codons: A Computational Approach and GFP-Reporter Cell-Based Assay 184
Bypass of cell cycle arrest induced by transient DNMT1 post-transcriptional silencing triggers aneuploidy in human cells 183
Retinoblastoma epidemiology: Does the evidence matter? 175
CENPA overexpression promotes genome instability in pRb-depleted human cells. 175
Inhibition of FTSJ1, a tryptophan tRNA-specific 2’-O-methyltransferase as possible mechanism to readthrough premature termination codons (UGAs) of the CFTR mRNA 173
Uno studio comparativo in silico sui possibili target di Ataluren e analoghi farmaci promotori di readthrough di codoni di stop prematuri 166
COMBINING TRANSLATION READTHROUGH INDUCING DRUGS AND NONSENSE MEDIATED DECAY PATWHAY INHIBITION TO THE CFTR RESCUE IN CYSTIC FIBROSIS CELL MODEL SYSTEM 165
Simultaneous Aurora-A/STK15 overexpression and centrosome amplification induce chromosomal instability in tumour cells with a MIN phenotype 163
P015 Translational readthrough inducing drugs: a study of toxicity in mice models and in vitro safety validation of the specific readthrough process. 163
p14(ARF) Prevents Proliferation of Aneuploid Cells by Inducing p53-Dependent Apoptosis 160
Exploring the readthrough of nonsense mutations by non-acidic Ataluren analogues selected by ligand-based virtual screening 156
Adenosine negatively regulates duodenal motility in mice: role of A1 and A2a receptors . 143
Perfluorocarbons-graphene oxide nanoplatforms as biocompatible oxygen reservoirs 143
Derivati Ossadiazolici per il trattamento della fibrosi cistica: Readthrough di mutazioni nonsense 140
Aurora-A transcriptional silencing and Vincristine treatment show a synergistic effect in human tumor cells 139
Rescuing the CFTR protein function: Introducing 1,3,4-oxadiazoles as translational readthrough inducing drugs 139
AZIONE READTHROUGH DI DERIVATI DEL PTC124 SU SISTEMI MODELLO CELLULARI E IN CELLULE DI EPITELIO BRONCHIALE-FC IB3.1 (CFTR F508/W1282X ) 132
Glucagon-like peptide-1 relaxes gastric antrum through nitric oxide in mice. 130
Targeting nonsense: Optimization of 1,2,4-oxadiazole trids to rescue cftr expression and functionality in cystic fibrosis cell model systems 130
Gastric relaxation induced by glucagon-like peptide-2 in mice fed a high-fat diet or fasted. 129
MAD2 depletion triggers premature cellular senescence in human primary fibroblasts by activating a P53 pathway preventing aneuploid cells propagation. 128
Functional inactivation of pRB results in aneuploid mammalian cells after release from a mitotic block 128
DNA demethylation caused By 5-Aza-2'-Deoxycytidine induces mitotic alterations and aneuploidy 126
RNAi mediated acute depletion of Retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation 125
Centrosome amplification induced by hydroxyurea leads to aneuploidy in pRB deficient human and mouse fibroblasts 122
Simultaneous reduction of MAD2 and BUBR1 expression induces mitotic spindle alterations associated with p53 dependent cell cycle arrest and death 120
Glucagon-like peptide-2 analog and inflammatory state in obese mice 120
Does the evidence matter in medicine? The retinoblastoma paradigm. 117
Strategies against nonsense: oxadiazoles as translational readthrough-inducing drugs (TRIDs) 117
RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts 116
Investigating REPAIRv2 as a Tool to Edit CFTR mRNA with Premature Stop Codons 116
Premature termination codon 124 derivatives as a novel approach to improve the read-through of premature amber and ochre stop codons 112
Pharmacophore-Based Design of New Chemical Scaffolds as Translational Readthrough-Inducing Drugs (TRIDs) 110
TRPM8 channel activation reduces the spontaneous contractions in human distal colon 108
DNMT1 depletion activates a pathway p14ARF/TP53 controlled that induces G1 arrest preventing DNA demethylation and aneuploidy 107
Optimization of a new lead promoting the readthrough of the nonsense mutations for CFTR rescue in human CF cells 106
PTC124 derivatives as a novel approach to improve the readthrough of premature stop codons in the CFTR gene. 105
Low doses of Hydroxyurea induce centrosome amplification and aneuploidy in primary human fibroblasts in culture 93
Micronuclei generation and chromosomal instability after RB interferences in human fibroblasts 92
Acute loss of pRB function induces centrosome amplification and aneuploidy both in murine and human fibroblasts 90
Gastric relaxation induced by glucagon-like peptide-2 and receptorial expression in fasted or high-fat diet fed mice. 89
Chromosomal instability promoted by RB depletion relied neither on p53 nor SAC dysfunction in HCT116 tumor cells 87
Aurora-A/STK15 transcriptional silencing and Vincristine treatment show a synergistic effect in human tumour cells 86
Identification and validation of novel molecules obtained by integrated computational and experimental approaches for the read-through of PTCs in CF cells 86
Rescuing CFTR Protein Function: 1,3,4-oxadiazoles versus 1,2,4-oxadiazoles as readthrough inducing drugs 85
A1 ADENOSINE RECEPTOR MODULATION OF CONTRACTILITY IN MOUSE DUODENUM LONGITUDINAL MUSCLE. 84
Evidence for region-specific effects of glucagone-like peptide-2 in mouse stomach 82
PTC124 DERIVATIVES AS A NOVEL APPROACH TO IMPROVE THE READTHROUGH OF PREMATURE AMBER AND OCHRE STOP CODONS 82
Translational Readthrough Inducing Drugs (TRIDs): a study of biodistribution evaluation in mice models 81
Identification of a new molecule with readthrough activity to rescue CFTR protein function 80
Acute loss of retinoblastoma function induces centrosomes amplification both in murine and human fibroblasts 79
Preventive Impact of Long-Term Ingestion of Chestnut Honey on Glucose Disorders and Neurodegeneration in Obese Mice 79
AURKA (aurora kinase A) 78
Valutazione dell'azione readthorough della molecola PTC124 su sistemi modello cellulari contenenti mutazioni non senso e in cellule epiteliali bronchiali IB3.1 (delF508/W1282X) derivate da pazienti affetti da fibrosi cistica. 78
Aneuploidy induced by MAD2 haploinsufficiency triggers premature senescence in human primary fibroblast 77
Inhalable nano into micro dry powders for ivacaftor delivery: the role of mannitol and cysteamine as mucus-active agents 77
Acute loss of retinoblastoma function induces centrosome amplification and aneuploidy both in human and murine primary fibroblasts 76
ADENOSINE IS A MODULATOR OF THE CONTRACTILITY OF THE DUODENAL LONGITUDINAL MUSCLE IN MICE 76
Readthrough Inducing Drugs (TRIDs) in human fibroblasts harboring the c.5047 C>T (R1683*) nonsense mutation 75
Nanopiattaforme di Ossido di Grafene perfluorurate: materiali biocompatibili con affinità per l'ossigeno 75
Nonsense codons suppression. An acute toxicity study of three optimized TRIDs in murine model, safety and tolerability evaluation 73
Aurora A overexpression leads centrosome amplification and aneuploidy in human colon cancer cells with MIN phenotype 73
Bypass of G1 arrest induced by DNMT1 posttranscriptional silencing triggers aneuploidy in human cells. 73
X CONVENTION OF INVESTIGATORS IN CYSTIC FIBROSIS. 73
EFFECTS OF PLK1 DEPLETION IN CENTROSOME DUPLICATIONS AND CELL CYCLEPROGRESSION IN HCT116 TUMOR CELLS. 72
DNA Methyltransferase1 post-transcriptional silencing induces aneuploidy and cell cycle arrest in human cells. 72
DNMT1 transient silencing induces aneuploidy, premature separated chromatids and centromeric chromatin alterations 69
Identification of pathways involved in aneuploidy onset and its tolerance using a DNA microarray approach 68
Hydroxyurea induces centrosome amplification and slowing down of cell cycle in colo-cancer cells SW480 67
Does GLP-2 receptor expression change dynamically in fed and fasted states? 67
Identification and validation of novel molecules obtained by integrated computational and experimental approaches for the readthrough of PTCs in CF cells 65
Effetti del Silenziamento dei geni Plk1, Brca1 e Rb nella duplicazione dei centrosomi in cellule tumorali HCT116 64
Missing evidences in cancer genetics: The retinoblastoma paradigm. 64
Evidence for region-specific effects of Glucagon-like Ppeptide-2 in mouse stomach” 64
Novel molecules for the readthrough of PTCs in biological model systems and in cystic fibrosis cells 64
Silencing of serine threonine kinase Aurora-2 gene cause G2/M arrest and apotosis in human carcinoma lung large cells 63
Silencing of serine threonine kinase Aurora-2 gene causes G2/M arrest and apoptosis in human carcinoma lung large cells. 63
“DNA Methyl transferase 1 post-trascriptional silencing indues aneuploidy and cell cycle arrest in human cells”, 62
Transient and stable depletion of RB induce different expression of genes involved in epigenetic modifications. 60
Effects of Plk1 depletion on centrosome duplication and cell cycle progression in HCT116 tumor cells 59
Transient silencing of MAD2 induces mitotic abnormalities and p21waf1 overexpression in primary human fibroblasts 59
PTC124 derivatives as a novel approach to improve the readthrough of premature stop codons in the CFTR gene 59
STK15 overexpression in HCT116 cells causes mitotic disorders and hypodiploidy associated with centrosome amplification. 58
Hydroxiurea induces centrosome amplification and slowing down of cell cycle in colo-cancer cells SW480 58
Effetti del silenziamento dei geni Plk1, Brca1 ed Rb nella duplicazione dei centrosomi in cellule tumorali HCT116 57
RB acute loss affects expression of mitotic genes and is associated with centrosome amplification and aneuploidy 56
RNA interference of MAD2 and BUBR1 genes causes mitotic spindle alterations, aneuploidy and cell cycle arrest p53-dependent. 56
pRb loss and chromosomal instability in human cells. 56
Identification of mechanism(s) leading to hyperdiploidy in progenitor tumor cells derived from MCF7 breast cancer cells 56
The retinoblastoma paradigm revisited 55
Inhibitory control of duodenal contractility by adenosine in mice 52
OXADIAZOLE DERIVATIVES FOR THE TREATMENT OF GENETIC DISEASES DUE TO NONSENSE MUTATIONS 51
Investigating the inhibition of FTSJ1 a tryptophan tRNA-specific 2’-O-methyltransferase by NV TRIDs, as a mechanism of readthrough in nonsense mutated CFTR 50
Rb depletion induces centrosome amplification and different exression of mitotic genes in HCT116 tumor cells 49
RESCUE OF LRBA GENE EXPRESSION IN PRIMARY HUMAN FIBROBLASTS CHARACTERISED BY NONSENSE MUTATION c. 5047 (C>T). 49
Unlocking Cellular Secrets: Charting Proteomic Frontiers in LRBA Deficiency Through the Lens of Readthrough Promoters 46
RESCUING P53 BY NEW TRANSLATIONAL READTHROUGH INDUCING DRUGS 46
Totale 9.848
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Categoria #
all - tutte 37.380
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37.380
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.143 0 0 0 0 0 226 189 106 179 183 157 103
2020/20211.381 57 133 39 134 194 67 130 82 127 124 135 159
2021/20221.230 80 291 29 24 30 40 37 78 148 167 67 239
2022/20231.741 164 171 54 317 174 272 130 99 172 46 85 57
2023/20241.086 73 125 53 99 85 160 107 161 5 34 18 166
2024/2025848 98 149 136 178 134 153 0 0 0 0 0 0
Totale 10.165