Archivio istituzionale della ricerca dell'Università degli Studi di Palermo

MELFI, Raffaella
 Distribuzione geografica
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Continente #
NA - Nord America 2.615
EU - Europa 1.815
AS - Asia 475
SA - Sud America 16
OC - Oceania 8
AF - Africa 6
Continente sconosciuto - Info sul continente non disponibili 5
Totale 4.940
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Nazione #
US - Stati Uniti d'America 2.600
IT - Italia 908
CN - Cina 278
FI - Finlandia 163
DE - Germania 154
IN - India 111
IE - Irlanda 109
UA - Ucraina 103
GB - Regno Unito 95
SE - Svezia 92
FR - Francia 36
BE - Belgio 34
RU - Federazione Russa 29
HK - Hong Kong 27
TR - Turchia 26
NL - Olanda 20
RO - Romania 19
ES - Italia 16
JP - Giappone 13
CA - Canada 12
PL - Polonia 12
AU - Australia 8
CL - Cile 8
GR - Grecia 5
BR - Brasile 4
CH - Svizzera 4
DZ - Algeria 4
KR - Corea 4
IR - Iran 3
MX - Messico 3
RS - Serbia 3
SI - Slovenia 3
BG - Bulgaria 2
EU - Europa 2
IL - Israele 2
LB - Libano 2
PE - Perù 2
PT - Portogallo 2
SK - Slovacchia (Repubblica Slovacca) 2
UY - Uruguay 2
XK - ???statistics.table.value.countryCode.XK??? 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AT - Austria 1
BD - Bangladesh 1
CZ - Repubblica Ceca 1
DK - Danimarca 1
ID - Indonesia 1
KZ - Kazakistan 1
LK - Sri Lanka 1
MY - Malesia 1
NO - Norvegia 1
PS - Palestinian Territory 1
SG - Singapore 1
TN - Tunisia 1
TW - Taiwan 1
UZ - Uzbekistan 1
ZA - Sudafrica 1
Totale 4.940
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Città #
Palermo 365
Fairfield 299
Ashburn 248
Chandler 244
Ann Arbor 171
Woodbridge 164
Wilmington 135
Houston 120
Seattle 114
Dublin 100
Cambridge 93
Hyderabad 87
Medford 79
Jacksonville 54
Nanjing 53
Princeton 51
Des Moines 49
New York 41
Ludwigshafen am Rhein 37
Bremen 36
Milan 32
Shenyang 31
Altamura 30
Dearborn 30
Jinan 26
Boardman 23
Brussels 23
Beijing 22
Lawrence 22
Tulsa 22
Naples 21
Clifton 18
London 18
Izmir 17
Redwood City 17
San Diego 17
Chikmagalūr 16
Nanchang 16
Philadelphia 16
Helsinki 15
Los Angeles 15
Rome 15
Hebei 13
Ningbo 13
Amsterdam 12
Catania 12
Central 12
Changsha 12
Tianjin 12
Volturara Irpina 11
Washington 11
Zhengzhou 11
Atlanta 9
Jiaxing 9
Taizhou 9
Trapani 9
Ferrara 8
Phoenix 8
Venice 8
Auburn Hills 7
Barcelona 7
Hong Kong 7
Lanzhou 7
San Paolo di Civitate 7
Chicago 6
Haikou 6
Hangzhou 6
Norwalk 6
Paris 6
Saint Petersburg 6
Florence 5
Flower Mound 5
Napoli 5
Tappahannock 5
Ali Mendjeli 4
Central District 4
Council Bluffs 4
Edinburgh 4
Frankfurt 4
Guangzhou 4
Jersey City 4
Kilburn 4
North Kansas City 4
Petralia Soprana 4
Pune 4
Ravenna 4
Redmond 4
Shanghai 4
Vicenza 4
Alcamo 3
Augusta 3
Belfast 3
Belgrade 3
Bonn 3
Erice 3
Falls Church 3
Gent 3
León 3
Litija 3
Madrid 3
Totale 3.365
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Nome #
Tracking the invasion of the red swamp crayfish Procambarus clarkii (Girard, 1852) (Decapoda Cambaridae) in Sicily: a “citizen science” approach 226
Caffeine boosts Ataluren's readthrough activity 171
Toward a Rationale for the PTC124 (Ataluren) Promoted Readthrough of Premature Stop Codons: A Computational Approach and GFP-Reporter Cell-Based Assay 170
Enhancement of premature stop codon readthrough in the CFTR gene by Ataluren (PTC124) derivatives 166
P015 Translational readthrough inducing drugs: a study of toxicity in mice models and in vitro safety validation of the specific readthrough process. 147
Exploring the readthrough of nonsense mutations by non-acidic Ataluren analogues selected by ligand-based virtual screening 144
Investigating CRISPR-CAS13b as a tool for the RNA editing of CFTR mRNA with premature stop codon 140
Down regulation of early sea urchin histone H2A gene relies on cis regulative sequences located in the 5’ and 3’ regions and including the enhancer blocker sns 131
The Compass-like Locus, Exclusive to the Ambulacrarians, Encodes a Chromatin Insulator Binding Protein in the Sea Urchin Embryo 130
Rescuing the CFTR protein function: Introducing 1,3,4-oxadiazoles as translational readthrough inducing drugs 129
Promoter activity of the sea urchin (Paracentrotus lividus) nucleosomal H3 and H2A and linker H1 a-histone genes is modulated by enhancer and chromatin insulator 122
Targeting nonsense: Optimization of 1,2,4-oxadiazole trids to rescue cftr expression and functionality in cystic fibrosis cell model systems 119
Constitutive Promoter Occupancy by the MBF-1 Activator and Chromatin Modification of the Developmental Regulated Sea Urchin alpha-H2A Histone Gene 113
The sea urchin sns insulator blocks CMV enhancer following integration in human cells 110
Investigating REPAIRv2 as a Tool to Edit CFTR mRNA with Premature Stop Codons 108
AZIONE READTHROUGH DI DERIVATI DEL PTC124 SU SISTEMI MODELLO CELLULARI E IN CELLULE DI EPITELIO BRONCHIALE-FC IB3.1 (CFTR F508/W1282X ) 106
Derivati Ossadiazolici per il trattamento della fibrosi cistica: Readthrough di mutazioni nonsense 106
Strategies against nonsense: oxadiazoles as translational readthrough-inducing drugs (TRIDs) 105
Down-regulation of early sea urchin histone H2A gene relies on cis regulative sequences located in the 5’ and 3’ regions including the enhancer blocker sns 102
PTC124 derivatives as a novel approach to improve the readthrough of premature stop codons in the CFTR gene. 98
Optimization of a new lead promoting the readthrough of the nonsense mutations for CFTR rescue in human CF cells 98
The sea urchin histone H2A enhancer-binding protein MBF-1 is needed for maximal expression also for the H3 gene, while is buffered by the sns5 insulator on its interaction with the downstream H1 promoter. 94
“Epigenetics of silencing of Paracentrotus lividus α-H2A gene” 94
Ruolo delle HDAC sul silenziamento genico nell’embrione di riccio di mare 92
Pharmacophore-Based Design of New Chemical Scaffolds as Translational Readthrough-Inducing Drugs (TRIDs) 92
Premature termination codon 124 derivatives as a novel approach to improve the read-through of premature amber and ochre stop codons 91
Can phthalates move into the eggs of the loggerhead sea turtle Caretta caretta? The case of the nests on the Linosa Island in the Mediterranean Sea 85
LA DINAMICA DELLA CROMATINA NELLA REGOLAZIONE DELL’ESPRESSIONEGENICA DELL’EMBRIONE DI RICCIO DI MARE 83
Characterization of a nuclear factor associated to the chromatin of sea urchin histone genes 83
Enhancer, chromatin insulator, non-coding RNA and α-histone gene expression during embryogenesis of the sea urchin Paracentrotus lividus. 82
CHOMATIN DYNAMIC AND REGULATION OF GENE EXSPRESSION IN THE SEA URCHIN EMBRYO 81
Identification and validation of novel molecules obtained by integrated computational and experimental approaches for the read-through of PTCs in CF cells 81
Rescuing CFTR Protein Function: 1,3,4-oxadiazoles versus 1,2,4-oxadiazoles as readthrough inducing drugs 77
PTC124 DERIVATIVES AS A NOVEL APPROACH TO IMPROVE THE READTHROUGH OF PREMATURE AMBER AND OCHRE STOP CODONS 74
Valutazione dell'azione readthorough della molecola PTC124 su sistemi modello cellulari contenenti mutazioni non senso e in cellule epiteliali bronchiali IB3.1 (delF508/W1282X) derivate da pazienti affetti da fibrosi cistica. 72
Reevaluating the function of a transcription factor: MBF-1 as a sea urchin chromatin organizer ? 72
Identification of a new molecule with readthrough activity to rescue CFTR protein function 72
Impact of Heavy Metals in Eggs and Tissues of C. caretta along the Sicilian Coast (Mediterranean Sea) 68
Translational Readthrough Inducing Drugs (TRIDs): a study of biodistribution evaluation in mice models 68
X CONVENTION OF INVESTIGATORS IN CYSTIC FIBROSIS. 65
Dinamica della cromatina nella regolazione del gene con homeobox Hbox12 in P. lividus. 65
Sea urchin HSF activity in vitro and in transgenic embryos 64
The genetic identity of the only Italian population of the genus Macroprotodon Guichenot, 1850 on the island of Lampedusa, Sicily 64
Identification and validation of novel molecules obtained by integrated computational and experimental approaches for the readthrough of PTCs in CF cells 62
Readthrough Inducing Drugs (TRIDs) in human fibroblasts harboring the c.5047 C>T (R1683*) nonsense mutation 60
Nonsense codons suppression. An acute toxicity study of three optimized TRIDs in murine model, safety and tolerability evaluation 59
PTC124 derivatives as a novel approach to improve the readthrough of premature stop codons in the CFTR gene 51
Presence and biodistribution of perfluorooctanoic acid (PFOA) in Paracentrotus lividus highlight its potential application for environmental biomonitoring 51
OXADIAZOLE DERIVATIVES FOR THE TREATMENT OF GENETIC DISEASES DUE TO NONSENSE MUTATIONS 48
RNA Editing Approaches for the correction of nonsense mutation in a cell model for Cystic Fibrosis 42
Novel molecules for the readthrough of PTCs in biological model systems and in cystic fibrosis cells 40
Integrated computational and experimental approaches for the identification of new molecules with readthrough activity on premature termination codons (PTCs) in cystic fibrosis cells 39
Identification and validation of novel molecules obtained by integrated computational and experimental approaches for the read-through of PTCs in CF cells. 39
Phylogenetic relationships of the italian populations of horseshoe whip snake hemorrhois hippocrepis (Serpentes, colubridae) 38
Investigating the inhibition of FTSJ1 a tryptophan tRNA-specific 2’-O-methyltransferase by NV TRIDs, as a mechanism of readthrough in nonsense mutated CFTR 33
Identification of a putative GAGA factor in P. lividus embryos 31
Identification of a putative regulator of early-histone gene expression of Paracentrotus lividus 28
Uptake and photoinduced degradation of phthalic acid esters (PAEs) in Ulva lactuca highlight its potential application in environmental bioremediation 27
Functional characterization of the enhancer blocking element of the sea urchin early histone gene cluster reveals insulator properties and three essential cis-acting sequences 27
Controlled uptake of PFOA in adult specimens of Paracentrotus lividus and evaluation of gene expression in their gonads and embryos 23
Regulation of the sea urchin early H2A histone gene expression depends on the modulator element and on sequences located near the 3' end 19
Assembly of Polycomb complexes and silencing mechanisms 19
Preliminary genetic characterisation of Southern Smooth Snake Coronella girondica (Serpentes, Colubridae) populations in Italy, with some considerations on their alpine distribution 19
Expression of homeobox-containing genes in the sea urchin (Parancentrotus lividus) embryo 18
Establishment of Polycomb silencing requires a transient interaction between PC and ESC 18
Gene expression during early embryogenesis of sea urchin: The histone and homeobox genes 18
Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites 17
Enhancer blocking activity located near the 3′ end of the sea urchin early H2A histone gene 15
Homeobox genes and sea urchin development 13
Spatially restricted expression of PlOtp, a Paracentrotus lividus Orthopedia-related homeobox gene, is correlated with oral ectodermal patterning and skeletal morphogenesis in late-cleavage sea urchin embryos 10
Phylogenetic affinities of the Italian population of Eastern Montpellier snake, Malpolon insignitus (Serpentes: Lamprophiidae) 10
Readthrough Approach Using NV Translational Readthrough-Inducing Drugs (TRIDs): A Study of the Possible Off-Target Effects on Natural Termination Codons (NTCs) on TP53 and Housekeeping Gene Expression 10
Homeobox-containing gene transiently expressed in a spatially restricted pattern in the early sea urchin embryo 9
Site-Specific RNA Editing of Stop Mutations in the CFTR mRNA of Human Bronchial Cultured Cells 9
Totale 5.362
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Categoria #
all - tutte 20.629
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20.629
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019112 0 0 0 0 0 0 0 0 0 0 66 46
2019/2020865 105 27 42 57 92 110 90 50 81 66 109 36
2020/2021685 40 35 45 61 116 28 36 42 51 87 61 83
2021/2022797 41 164 23 36 42 24 52 68 64 97 56 130
2022/20231.190 88 119 44 148 98 162 72 72 130 120 66 71
2023/2024854 54 90 72 80 90 167 115 157 3 26 0 0
Totale 5.362