Archivio istituzionale della ricerca dell'Università degli Studi di Palermo

MELFI, Raffaella
 Distribuzione geografica
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Continente #
NA - Nord America 2.790
EU - Europa 2.132
AS - Asia 805
AF - Africa 27
SA - Sud America 16
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 10
Totale 5.790
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Nazione #
US - Stati Uniti d'America 2.774
IT - Italia 1.080
CN - Cina 318
SG - Singapore 253
FI - Finlandia 225
DE - Germania 190
IN - India 116
IE - Irlanda 113
GB - Regno Unito 106
UA - Ucraina 103
SE - Svezia 94
FR - Francia 42
BE - Belgio 35
HK - Hong Kong 32
TR - Turchia 32
RU - Federazione Russa 29
NL - Olanda 26
JP - Giappone 25
ES - Italia 22
CI - Costa d'Avorio 20
RO - Romania 19
CA - Canada 13
PL - Polonia 12
AU - Australia 10
CL - Cile 8
XK - ???statistics.table.value.countryCode.XK??? 7
IL - Israele 6
AT - Austria 5
GR - Grecia 5
IR - Iran 5
BR - Brasile 4
CH - Svizzera 4
DZ - Algeria 4
KR - Corea 4
NO - Norvegia 4
PT - Portogallo 4
MX - Messico 3
QA - Qatar 3
RS - Serbia 3
SI - Slovenia 3
BG - Bulgaria 2
CZ - Repubblica Ceca 2
EU - Europa 2
KZ - Kazakistan 2
LB - Libano 2
PE - Perù 2
SK - Slovacchia (Repubblica Slovacca) 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BD - Bangladesh 1
DK - Danimarca 1
ID - Indonesia 1
LK - Sri Lanka 1
LT - Lituania 1
MA - Marocco 1
MY - Malesia 1
PS - Palestinian Territory 1
TN - Tunisia 1
TW - Taiwan 1
UZ - Uzbekistan 1
ZA - Sudafrica 1
Totale 5.790
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Città #
Palermo 425
Fairfield 299
Ashburn 266
Chandler 244
Singapore 215
Ann Arbor 171
Woodbridge 164
Wilmington 135
Houston 122
Seattle 114
Dublin 104
Cambridge 93
Hyderabad 87
Medford 79
Helsinki 77
Jacksonville 54
Nanjing 53
Princeton 51
Des Moines 49
Milan 49
New York 41
Ludwigshafen am Rhein 37
Bremen 36
Shenyang 31
Altamura 30
Dearborn 30
Naples 28
Santa Clara 28
Jinan 26
Rome 25
Boardman 24
Brussels 24
Beijing 23
Lawrence 22
Tulsa 22
Abidjan 20
London 20
Clifton 18
Philadelphia 18
Falkenstein 17
Izmir 17
Redwood City 17
San Diego 17
Chikmagalūr 16
Columbus 16
Los Angeles 16
Nanchang 16
Catania 15
Amsterdam 14
Ningbo 14
Changsha 13
Hebei 13
Barcelona 12
Central 12
Hong Kong 12
Tianjin 12
Turin 12
Volturara Irpina 11
Washington 11
Zhengzhou 11
Jiaxing 10
Atlanta 9
Florence 9
Taizhou 9
Trapani 9
Ferrara 8
Phoenix 8
Venice 8
Auburn Hills 7
Bristol 7
Lanzhou 7
San Paolo di Civitate 7
Carini 6
Carovigno 6
Chicago 6
Dallas 6
Haikou 6
Hangzhou 6
Norwalk 6
Paris 6
Saint Petersburg 6
Flower Mound 5
Frankfurt am Main 5
Guangzhou 5
Hoover 5
Napoli 5
Prizren 5
Tappahannock 5
Tel Aviv 5
Verona 5
Ali Mendjeli 4
Berlin 4
Central District 4
Chevy Chase 4
Council Bluffs 4
Edinburgh 4
Frankfurt 4
Jersey City 4
Kilburn 4
Magenta 4
Totale 3.885
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Nome #
Tracking the invasion of the red swamp crayfish Procambarus clarkii (Girard, 1852) (Decapoda Cambaridae) in Sicily: a “citizen science” approach 243
Caffeine boosts Ataluren's readthrough activity 189
Enhancement of premature stop codon readthrough in the CFTR gene by Ataluren (PTC124) derivatives 187
Toward a Rationale for the PTC124 (Ataluren) Promoted Readthrough of Premature Stop Codons: A Computational Approach and GFP-Reporter Cell-Based Assay 184
P015 Translational readthrough inducing drugs: a study of toxicity in mice models and in vitro safety validation of the specific readthrough process. 163
Investigating CRISPR-CAS13b as a tool for the RNA editing of CFTR mRNA with premature stop codon 157
Exploring the readthrough of nonsense mutations by non-acidic Ataluren analogues selected by ligand-based virtual screening 156
Derivati Ossadiazolici per il trattamento della fibrosi cistica: Readthrough di mutazioni nonsense 140
Rescuing the CFTR protein function: Introducing 1,3,4-oxadiazoles as translational readthrough inducing drugs 139
Down regulation of early sea urchin histone H2A gene relies on cis regulative sequences located in the 5’ and 3’ regions and including the enhancer blocker sns 135
The Compass-like Locus, Exclusive to the Ambulacrarians, Encodes a Chromatin Insulator Binding Protein in the Sea Urchin Embryo 132
AZIONE READTHROUGH DI DERIVATI DEL PTC124 SU SISTEMI MODELLO CELLULARI E IN CELLULE DI EPITELIO BRONCHIALE-FC IB3.1 (CFTR F508/W1282X ) 132
Targeting nonsense: Optimization of 1,2,4-oxadiazole trids to rescue cftr expression and functionality in cystic fibrosis cell model systems 131
Promoter activity of the sea urchin (Paracentrotus lividus) nucleosomal H3 and H2A and linker H1 a-histone genes is modulated by enhancer and chromatin insulator 130
Constitutive Promoter Occupancy by the MBF-1 Activator and Chromatin Modification of the Developmental Regulated Sea Urchin alpha-H2A Histone Gene 121
Strategies against nonsense: oxadiazoles as translational readthrough-inducing drugs (TRIDs) 117
Investigating REPAIRv2 as a Tool to Edit CFTR mRNA with Premature Stop Codons 116
The sea urchin sns insulator blocks CMV enhancer following integration in human cells 114
Premature termination codon 124 derivatives as a novel approach to improve the read-through of premature amber and ochre stop codons 112
Pharmacophore-Based Design of New Chemical Scaffolds as Translational Readthrough-Inducing Drugs (TRIDs) 110
Optimization of a new lead promoting the readthrough of the nonsense mutations for CFTR rescue in human CF cells 106
Down-regulation of early sea urchin histone H2A gene relies on cis regulative sequences located in the 5’ and 3’ regions including the enhancer blocker sns 105
PTC124 derivatives as a novel approach to improve the readthrough of premature stop codons in the CFTR gene. 105
Can phthalates move into the eggs of the loggerhead sea turtle Caretta caretta? The case of the nests on the Linosa Island in the Mediterranean Sea 105
The sea urchin histone H2A enhancer-binding protein MBF-1 is needed for maximal expression also for the H3 gene, while is buffered by the sns5 insulator on its interaction with the downstream H1 promoter. 100
Ruolo delle HDAC sul silenziamento genico nell’embrione di riccio di mare 99
Characterization of a nuclear factor associated to the chromatin of sea urchin histone genes 98
“Epigenetics of silencing of Paracentrotus lividus α-H2A gene” 97
CHOMATIN DYNAMIC AND REGULATION OF GENE EXSPRESSION IN THE SEA URCHIN EMBRYO 90
Enhancer, chromatin insulator, non-coding RNA and α-histone gene expression during embryogenesis of the sea urchin Paracentrotus lividus. 90
Impact of Heavy Metals in Eggs and Tissues of C. caretta along the Sicilian Coast (Mediterranean Sea) 87
LA DINAMICA DELLA CROMATINA NELLA REGOLAZIONE DELL’ESPRESSIONEGENICA DELL’EMBRIONE DI RICCIO DI MARE 86
Identification and validation of novel molecules obtained by integrated computational and experimental approaches for the read-through of PTCs in CF cells 86
Rescuing CFTR Protein Function: 1,3,4-oxadiazoles versus 1,2,4-oxadiazoles as readthrough inducing drugs 85
PTC124 DERIVATIVES AS A NOVEL APPROACH TO IMPROVE THE READTHROUGH OF PREMATURE AMBER AND OCHRE STOP CODONS 82
Dinamica della cromatina nella regolazione del gene con homeobox Hbox12 in P. lividus. 82
Translational Readthrough Inducing Drugs (TRIDs): a study of biodistribution evaluation in mice models 81
Reevaluating the function of a transcription factor: MBF-1 as a sea urchin chromatin organizer ? 81
Identification of a new molecule with readthrough activity to rescue CFTR protein function 80
Valutazione dell'azione readthorough della molecola PTC124 su sistemi modello cellulari contenenti mutazioni non senso e in cellule epiteliali bronchiali IB3.1 (delF508/W1282X) derivate da pazienti affetti da fibrosi cistica. 78
Readthrough Inducing Drugs (TRIDs) in human fibroblasts harboring the c.5047 C>T (R1683*) nonsense mutation 75
Nonsense codons suppression. An acute toxicity study of three optimized TRIDs in murine model, safety and tolerability evaluation 73
X CONVENTION OF INVESTIGATORS IN CYSTIC FIBROSIS. 73
The genetic identity of the only Italian population of the genus Macroprotodon Guichenot, 1850 on the island of Lampedusa, Sicily 73
Sea urchin HSF activity in vitro and in transgenic embryos 72
RNA Editing Approaches for the correction of nonsense mutation in a cell model for Cystic Fibrosis 70
Identification and validation of novel molecules obtained by integrated computational and experimental approaches for the readthrough of PTCs in CF cells 65
Novel molecules for the readthrough of PTCs in biological model systems and in cystic fibrosis cells 64
Presence and biodistribution of perfluorooctanoic acid (PFOA) in Paracentrotus lividus highlight its potential application for environmental biomonitoring 62
PTC124 derivatives as a novel approach to improve the readthrough of premature stop codons in the CFTR gene 59
OXADIAZOLE DERIVATIVES FOR THE TREATMENT OF GENETIC DISEASES DUE TO NONSENSE MUTATIONS 51
Investigating the inhibition of FTSJ1 a tryptophan tRNA-specific 2’-O-methyltransferase by NV TRIDs, as a mechanism of readthrough in nonsense mutated CFTR 50
Phylogenetic relationships of the italian populations of horseshoe whip snake hemorrhois hippocrepis (Serpentes, colubridae) 47
Unlocking Cellular Secrets: Charting Proteomic Frontiers in LRBA Deficiency Through the Lens of Readthrough Promoters 46
RESCUING P53 BY NEW TRANSLATIONAL READTHROUGH INDUCING DRUGS 46
Integrated computational and experimental approaches for the identification of new molecules with readthrough activity on premature termination codons (PTCs) in cystic fibrosis cells 43
Identification and validation of novel molecules obtained by integrated computational and experimental approaches for the read-through of PTCs in CF cells. 42
Promoting readthrough of nonsense mutations in CF mouse model: Biodistribution and efficacy of NV848 in rescuing CFTR protein expression 41
Identification of a putative regulator of early-histone gene expression of Paracentrotus lividus 35
Controlled uptake of PFOA in adult specimens of Paracentrotus lividus and evaluation of gene expression in their gonads and embryos 34
Identification of a putative GAGA factor in P. lividus embryos 34
Functional characterization of the enhancer blocking element of the sea urchin early histone gene cluster reveals insulator properties and three essential cis-acting sequences 33
Uptake and photoinduced degradation of phthalic acid esters (PAEs) in Ulva lactuca highlight its potential application in environmental bioremediation 32
Preliminary genetic characterisation of Southern Smooth Snake Coronella girondica (Serpentes, Colubridae) populations in Italy, with some considerations on their alpine distribution 27
Readthrough Approach Using NV Translational Readthrough-Inducing Drugs (TRIDs): A Study of the Possible Off-Target Effects on Natural Termination Codons (NTCs) on TP53 and Housekeeping Gene Expression 24
Gene expression during early embryogenesis of sea urchin: The histone and homeobox genes 24
Regulation of the sea urchin early H2A histone gene expression depends on the modulator element and on sequences located near the 3' end 23
Assembly of Polycomb complexes and silencing mechanisms 23
Enhancer blocking activity located near the 3′ end of the sea urchin early H2A histone gene 23
Expression of homeobox-containing genes in the sea urchin (Parancentrotus lividus) embryo 21
Establishment of Polycomb silencing requires a transient interaction between PC and ESC 21
Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites 20
Phylogenetic affinities of the Italian population of Eastern Montpellier snake, Malpolon insignitus (Serpentes: Lamprophiidae) 16
Site-Specific RNA Editing of Stop Mutations in the CFTR mRNA of Human Bronchial Cultured Cells 16
Homeobox genes and sea urchin development 16
Spatially restricted expression of PlOtp, a Paracentrotus lividus Orthopedia-related homeobox gene, is correlated with oral ectodermal patterning and skeletal morphogenesis in late-cleavage sea urchin embryos 15
Homeobox-containing gene transiently expressed in a spatially restricted pattern in the early sea urchin embryo 12
Totale 6.232
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Categoria #
all - tutte 26.213
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 26.213
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020542 0 0 0 0 0 110 90 50 81 66 109 36
2020/2021685 40 35 45 61 116 28 36 42 51 87 61 83
2021/2022797 41 164 23 36 42 24 52 68 64 97 56 130
2022/20231.190 88 119 44 148 98 162 72 72 130 120 66 71
2023/20241.007 54 90 72 80 90 167 115 157 3 26 14 139
2024/2025717 66 120 84 139 114 194 0 0 0 0 0 0
Totale 6.232