Cluster visual field progression and its relationship with optic disc changes

Purpose Glaucoma diagnosis and follow up of progression is often based on structural and functional assessments. This study aimed to assess clustered progression and evaluate its correlation with the corresponding disc changes (RA sectors) obtained from HRT examinations. Methods 51 eyes from OHT and glaucoma patients with a minimum of 5 reliable visual ᴀ밄eld tests (HFA II i 24-2) and HRT with a follow-up >4 years were analyzed retrospectively. Linear regression of clusters deᴀ밄ned by the Glaucoma Hemiᴀ밄eld Test (GHT) was performed based on the mean threshold in each cluster. Global and sectoral rates of change in RAs were assessed and correlated with functional clustered measures. Clustered rates of VF and RA change were ᴀ밄agged as statistically signiᴀ밄cant progression if the gradients over time were negative with p<0.05.