LA MONICA, Gabriele
LA MONICA, Gabriele
Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche
Antiproliferative Activity Predictor: A New Reliable In Silico Tool for Drug Response Prediction against NCI60 Panel
2022-11-19 Martorana A.; La Monica G.; Bono A.; Mannino S.; Buscemi S.; Palumbo Piccionello A.; Gentile C.; Lauria A.; Peri D.
Antiproliferative Activity Predictor: un nuovo tool in silico per predire l’attività antiproliferativa nei confronti del pannello NCI60
2022-12-01 Gabriele La Monica, Annamaria Martorana, Alessia Bono, Salvatore Mannino, Silvestre Buscemi, Antonio Palumbo Piccionello, Carla Gentile, Daniele Peri, Antonino Lauria
Antiproliferative properties and g-quadruplex-binding of symmetrical naphtho[1,2-b:8,7-b’]dithiophene derivatives
2021-07-16 Lauria A.; La Monica G.; Terenzi A.; Mannino G.; Bonsignore R.; Bono A.; Almerico A.M.; Barone G.; Gentile C.; Martorana A.
Bioisosteric heterocyclic analogues of natural bioactive flavonoids by scaffold-hopping approaches: State-of-the-art and perspectives in medicinal chemistry
2024-07-15 La Monica, Gabriele; Bono, Alessia; Alamia, Federica; Lauria, Antonino; Martorana, Annamaria
Correlation between cell line chemosensitivity and protein expression pattern as new approach for the design of targeted anticancer small molecules
2022-11-15
Design and Synthesis of Novel Thieno[3,2-c]quinoline Compounds with Antiproliferative Activity on RET-Dependent Medullary Thyroid Cancer Cells
2023-09-26 La Monica, Gabriele; Pizzolanti, Giuseppe; Baiamonte, Concetta; Bono, Alessia; Alamia, Federica; Mingoia, Francesco; Lauria, Antonino; Martorana, Annamaria
Development of an inhibitor of the mutagenic SOS response that suppresses the evolution of quinolone antibiotic resistance
2024-05-01 Bradbury J.D.; Hodgkinson T.; Thomas A.M.; Tanwar O.; La Monica G.; Rogga V.V.; Mackay L.J.; Taylor E.K.; Gilbert K.; Zhu Y.; Sefton A.Y.; Edwards A.M.; Gray-Hammerton C.J.; Smith G.R.; Roberts P.M.; Walsh T.R.; Lanyon-Hogg T.
Identification of biological targets through the correlation between cell line chemosensitivity and protein expression pattern
2021-10-01 Lauria, Antonino; La Monica, Gabriele; Gentile, Carla; Mannino, Giuseppe; Martorana, Annamaria; Peri, Daniele
In Silico Design of New Dual Inhibitors of SARS-CoV-2 MPRO through Ligand- and Structure-Based Methods
2023-05-06 Bono, Alessia; Lauria, Antonino; La Monica, Gabriele; Alamia, Federica; Mingoia, Francesco; Martorana, Annamaria
In silico identification of small molecules as new cdc25 inhibitors through the correlation between chemosensitivity and protein expression pattern
2021-01-01 Lauria A.; Martorana A.; Monica G.L.; Mannino S.; Mannino G.; Peri D.; Gentile C.
In silico lead optimization and synthesis of a new series of thieno[3,2-c]quinoline with antiproliferative activity on RET-dependent medullary thyroid cancer cells
2023-12-11 Gabriele La Monica; Giuseppe Pizzolanti; Concetta Baiamonte; Alessia Bono; Federica Alamia; Giuseppe Siragusa; Francesco Mingoia; Antonino Lauria; Annamaria Martorana
In Silico Mixed Ligand/Structure-Based Design of New CDK-1/PARP-1 Dual Inhibitors as Anti-Breast Cancer Agents
2023-09-06 Bono, Alessia; La Monica, Gabriele; Alamia, Federica; Mingoia, Francesco; Gentile, Carla; Peri, Daniele; Lauria, Antonino; Martorana, Annamaria
New small molecules for the Treatment of TNBC innovative Polypharmacological In Silico Approach
2024-06-04 Federica Alamia, Gabriele La Monica, Alessia Bono, Antonino Lauria, Annamaria Martorana.
Off-target-based design of selective hiv-1 protease inhibitors
2021-01-01 La Monica G.; Lauria A.; Bono A.; Martorana A.
One pot-like regiospecific access to 1-aryl-1H-pyrazol-3(2H)-one derivatives and evaluation of the anticancer activity
2022-04-04 Mingoia F.; Panzeca G.; Vitale M.C.; La Monica G.; Bono A.; Lauria A.; Martorana A.
Quinoline anticancer agents active on DNA and DNA-interacting proteins: From classical to emerging therapeutic targets
2021-01-01 Lauria, Antonino; La Monica, Gabriele; Bono, Alessia; Martorana, Annamaria
Quinoline-based molecules targeting c-Met, EGF, and VEGF receptors and the proteins involved in related carcinogenic pathways
2020-01-01 Martorana A.; la Monica G.; Lauria A.
Scaffold-Hopping Strategies in Aurone Optimization: A Comprehensive Review of Synthetic Procedures and Biological Activities of Nitrogen and Sulfur Analogues
2024-06-13 La Monica, Gabriele; Alamia, Federica; Bono, Alessia; Lauria, Antonino; Martorana, Annamaria
Synthesis of new antiproliferative 1,3,4-substituted-pyrrolo[3,2-c]quinoline derivatives, biological and in silico insights
2023-06-01 Mingoia F.; Di Sano C.; D'Anna C.; Fazzari M.; Minafra L.; Bono A.; La Monica G.; Martorana A.; Almerico A.M.; Lauria A.
Targeting SARS-CoV-2 Main Protease for Treatment of COVID-19: Covalent Inhibitors Structure-Activity Relationship Insights and Evolution Perspectives
2022-09-28 La Monica G.; Bono A.; Lauria A.; Martorana A.