Sfoglia per Autore
Recent advances in computational design of potent aromatase inhibitors: open-eye on endocrine-resistant breast cancers
2019-10-03 Spinello A.; Ritacco I.; Magistrato A.
All-Atom simulations disclose how cytochrome reductase reshapes the substrate access/egress routes of its partner cyp450s
2020-01-27 Ritacco I.; Saltalamacchia A.; Spinello A.; Ippoliti E.; Magistrato A.
Targeting Orthosteric and Allosteric Pockets of Aromatase via Dual-Mode Novel Azole Inhibitors
2020-03-23 Caciolla J.; Spinello A.; Martini S.; Bisi A.; Zaffaroni N.; Gobbi S.; Magistrato A.
Is the Rigidity of SARS-CoV-2 Spike Receptor-Binding Motif the Hallmark for Its Enhanced Infectivity? Insights from All-Atom Simulations
2020-05-28 Spinello A.; Saltalamacchia A.; Magistrato A.
Molecular basis for endocrine disruption by pesticides targeting aromatase and estrogen receptor
2020-08-05 Zhang C.; Schiliro T.; Gea M.; Bianchi S.; Spinello A.; Magistrato A.; Gilardi G.; Di Nardo G.
All-atom simulations to studying metallodrugs/target interactions
2021-04-01 Janos P.; Spinello A.; Magistrato A.
Molecular Mechanisms of the Blockage of Glioblastoma Motility
2021-04-16 Xu J.; Simonelli F.; Li X.; Spinello A.; Laporte S.; Torre V.; Magistrato A.
Frontiers of metal-coordinating drug design
2021-05-04 Palermo G.; Spinello A.; Saha A.; Magistrato A.
Allosteric Cross-Talk among Spike’s Receptor-Binding Domain Mutations of the SARS-CoV-2 South African Variant Triggers an Effective Hijacking of Human Cell Receptor
2021-06-23 Spinello A.; Saltalamacchia A.; Borisek J.; Magistrato A.
Computing Metal-Binding Proteins for Therapeutic Benefit
2021-07-06 Spinello A.; Borisek J.; Pavlin M.; Janos P.; Magistrato A.
Investigating the molecular mechanism of h3b‐8800: A splicing modulator inducing preferential lethality in spliceosome‐mutant cancers
2021-10-18 Spinello A.; Borisek J.; Malcovati L.; Magistrato A.
Balanced dual acting compounds targeting aromatase and estrogen receptor α as an emerging therapeutic opportunity to counteract estrogen responsive breast cancer
2021-11-15 Caciolla J.; Martini S.; Spinello A.; Pavlin M.; Turrini E.; Simonelli F.; Belluti F.; Rampa A.; Bisi A.; Fimognari C.; Zaffaroni N.; Gobbi S.; Magistrato A.
Molecular Basis of SARS-CoV-2 Nsp1-Induced Immune Translational Shutdown as Revealed by All-Atom Simulations
2021-12-01 Borisek J.; Spinello A.; Magistrato A.
Role of computational and structural biology in the development of small-molecule modulators of the spliceosome
2022-10-03 Rozza, Riccardo; Janoš, Pavel; Spinello, Angelo; Magistrato, Alessandra
Anticancer Activity, Reduction Mechanism and G-Quadruplex DNA Binding of a Redox-Activated Platinum(IV)–Salphen Complex
2022-12-08 Vigna, Vincenzo; Scoditti, Stefano; Spinello, Angelo; Mazzone, Gloria; Sicilia, Emilia
A Novel Peptide with Antifungal Activity from Red Swamp Crayfish Procambarus clarkii
2022-12-10 Punginelli, Diletta; Catania, Valentina; Vazzana, Mirella; Mauro, Manuela; Spinello, Angelo; Barone, Giampaolo; Barberi, Giuseppe; Fiorica, Calogero; Vitale, Maria; Cunsolo, Vincenzo; Saletti, Rosaria; Di Francesco, Antonella; Arizza, Vincenzo; Schillaci, Domenico
Single-digit nanomolar inhibitors lock the aromatase active site via a dualsteric targeting strategy
2022-12-15 Caciolla, Jessica; Martini, Silvia; Spinello, Angelo; Belluti, Federica; Bisi, Alessandra; Zaffaroni, Nadia; Magistrato, Alessandra; Gobbi, Silvia
Predicting the Three-Dimensional Structure of the c-KIT Proto-Oncogene Promoter and the Dynamics of Its Strongly Coupled Guanine Quadruplexes
2023-01-01 Bignon E.; Spinello A.; Miclot T.; D'Anna L.; Ducani C.; Grandemange S.; Barone G.; Monari A.; Terenzi A.
Mechanism of the Covalent Inhibition of Human Transmembrane Protease Serine 2 as an Original Antiviral Strategy
2023-01-01 Spinello A.; D'Anna L.; Bignon E.; Miclot T.; Grandemange S.; Terenzi A.; Barone G.; Barbault F.; Monari A.
Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment
2023-03-29 Gobbi, Silvia; Martini, Silvia; Rozza, Riccardo; Spinello, Angelo; Caciolla, Jessica; Rampa, Angela; Belluti, Federica; Zaffaroni, Nadia; Magistrato, Alessandra; Bisi, Alessandra
| Data di pubblicazione | Titolo | Autori | Tipologia | Autore(i) | File |
|---|---|---|---|---|---|
| 3-ott-2019 | Recent advances in computational design of potent aromatase inhibitors: open-eye on endocrine-resistant breast cancers | Spinello A. + | 01 - Contributo in rivista::1.01 Articolo in rivista | Spinello A.; Ritacco I.; Magistrato A. | |
| 27-gen-2020 | All-Atom simulations disclose how cytochrome reductase reshapes the substrate access/egress routes of its partner cyp450s | Spinello A. + | 01 - Contributo in rivista::1.01 Articolo in rivista | Ritacco I.; Saltalamacchia A.; Spinello A.; Ippoliti E.; Magistrato A. | |
| 23-mar-2020 | Targeting Orthosteric and Allosteric Pockets of Aromatase via Dual-Mode Novel Azole Inhibitors | Spinello A. + | 01 - Contributo in rivista::1.01 Articolo in rivista | Caciolla J.; Spinello A.; Martini S.; Bisi A.; Zaffaroni N.; Gobbi S.; Magistrato A. | |
| 28-mag-2020 | Is the Rigidity of SARS-CoV-2 Spike Receptor-Binding Motif the Hallmark for Its Enhanced Infectivity? Insights from All-Atom Simulations | Spinello A. + | 01 - Contributo in rivista::1.01 Articolo in rivista | Spinello A.; Saltalamacchia A.; Magistrato A. | |
| 5-ago-2020 | Molecular basis for endocrine disruption by pesticides targeting aromatase and estrogen receptor | Spinello A. + | 01 - Contributo in rivista::1.01 Articolo in rivista | Zhang C.; Schiliro T.; Gea M.; Bianchi S.; Spinello A.; Magistrato A.; Gilardi G.; Di Nardo G. | |
| 1-apr-2021 | All-atom simulations to studying metallodrugs/target interactions | Spinello A. + | 01 - Contributo in rivista::1.01 Articolo in rivista | Janos P.; Spinello A.; Magistrato A. | |
| 16-apr-2021 | Molecular Mechanisms of the Blockage of Glioblastoma Motility | Spinello A. + | 01 - Contributo in rivista::1.01 Articolo in rivista | Xu J.; Simonelli F.; Li X.; Spinello A.; Laporte S.; Torre V.; Magistrato A. | |
| 4-mag-2021 | Frontiers of metal-coordinating drug design | Spinello A. + | 01 - Contributo in rivista::1.01 Articolo in rivista | Palermo G.; Spinello A.; Saha A.; Magistrato A. | |
| 23-giu-2021 | Allosteric Cross-Talk among Spike’s Receptor-Binding Domain Mutations of the SARS-CoV-2 South African Variant Triggers an Effective Hijacking of Human Cell Receptor | Spinello A. + | 01 - Contributo in rivista::1.01 Articolo in rivista | Spinello A.; Saltalamacchia A.; Borisek J.; Magistrato A. | |
| 6-lug-2021 | Computing Metal-Binding Proteins for Therapeutic Benefit | Spinello A. + | 01 - Contributo in rivista::1.01 Articolo in rivista | Spinello A.; Borisek J.; Pavlin M.; Janos P.; Magistrato A. | |
| 18-ott-2021 | Investigating the molecular mechanism of h3b‐8800: A splicing modulator inducing preferential lethality in spliceosome‐mutant cancers | Spinello A. + | 01 - Contributo in rivista::1.01 Articolo in rivista | Spinello A.; Borisek J.; Malcovati L.; Magistrato A. | |
| 15-nov-2021 | Balanced dual acting compounds targeting aromatase and estrogen receptor α as an emerging therapeutic opportunity to counteract estrogen responsive breast cancer | Spinello A.Zaffaroni N. + | 01 - Contributo in rivista::1.01 Articolo in rivista | Caciolla J.; Martini S.; Spinello A.; Pavlin M.; Turrini E.; Simonelli F.; Belluti F.; Rampa A.; Bisi A.; Fimognari C.; Zaffaroni N.; Gobbi S.; Magistrato A. | |
| 1-dic-2021 | Molecular Basis of SARS-CoV-2 Nsp1-Induced Immune Translational Shutdown as Revealed by All-Atom Simulations | Spinello A. + | 01 - Contributo in rivista::1.01 Articolo in rivista | Borisek J.; Spinello A.; Magistrato A. | |
| 3-ott-2022 | Role of computational and structural biology in the development of small-molecule modulators of the spliceosome | Spinello, Angelo + | 01 - Contributo in rivista::1.09 Review essay (rassegna critica) | Rozza, Riccardo; Janoš, Pavel; Spinello, Angelo; Magistrato, Alessandra | |
| 8-dic-2022 | Anticancer Activity, Reduction Mechanism and G-Quadruplex DNA Binding of a Redox-Activated Platinum(IV)–Salphen Complex | Spinello, Angelo + | 01 - Contributo in rivista::1.01 Articolo in rivista | Vigna, Vincenzo; Scoditti, Stefano; Spinello, Angelo; Mazzone, Gloria; Sicilia, Emilia | |
| 10-dic-2022 | A Novel Peptide with Antifungal Activity from Red Swamp Crayfish Procambarus clarkii | Punginelli, DilettaCatania, ValentinaVazzana, MirellaMauro, ManuelaSpinello, AngeloBarone, GiampaoloBarberi, GiuseppeFiorica, CalogeroArizza, VincenzoSchillaci, Domenico + | 01 - Contributo in rivista::1.01 Articolo in rivista | Punginelli, Diletta; Catania, Valentina; Vazzana, Mirella; Mauro, Manuela; Spinello, Angelo; Barone, Giampaolo; Barberi, Giuseppe; Fiorica, Calogero; Vitale, Maria; Cunsolo, Vincenzo; Saletti, Rosaria; Di Francesco, Antonella; Arizza, Vincenzo; Schillaci, Domenico | |
| 15-dic-2022 | Single-digit nanomolar inhibitors lock the aromatase active site via a dualsteric targeting strategy | Spinello, Angelo + | 01 - Contributo in rivista::1.01 Articolo in rivista | Caciolla, Jessica; Martini, Silvia; Spinello, Angelo; Belluti, Federica; Bisi, Alessandra; Zaffaroni, Nadia; Magistrato, Alessandra; Gobbi, Silvia | |
| 1-gen-2023 | Predicting the Three-Dimensional Structure of the c-KIT Proto-Oncogene Promoter and the Dynamics of Its Strongly Coupled Guanine Quadruplexes | Spinello A.Miclot T.D'Anna L.Barone G.Terenzi A. + | 01 - Contributo in rivista::1.01 Articolo in rivista | Bignon E.; Spinello A.; Miclot T.; D'Anna L.; Ducani C.; Grandemange S.; Barone G.; Monari A.; Terenzi A. | |
| 1-gen-2023 | Mechanism of the Covalent Inhibition of Human Transmembrane Protease Serine 2 as an Original Antiviral Strategy | Spinello A.D'Anna L.Miclot T.Grandemange S.Terenzi A.Barone G.Monari A. + | 01 - Contributo in rivista::1.01 Articolo in rivista | Spinello A.; D'Anna L.; Bignon E.; Miclot T.; Grandemange S.; Terenzi A.; Barone G.; Barbault F.; Monari A. | |
| 29-mar-2023 | Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment | Spinello, Angelo + | 01 - Contributo in rivista::1.01 Articolo in rivista | Gobbi, Silvia; Martini, Silvia; Rozza, Riccardo; Spinello, Angelo; Caciolla, Jessica; Rampa, Angela; Belluti, Federica; Zaffaroni, Nadia; Magistrato, Alessandra; Bisi, Alessandra |
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