Ancient human genomes suggest three ancestral
populations for present-day Europeans

Lazaridis, I; Patterson, P; Mittnik, A; Renaud, G; Mallick, S; Kirsanow, K; Sudmant, P; Schraiber, J; Castellano, S; Lipson, M; Berger, B; Economou, C; Bollongino, R; Fu, Q; Bos, K; Nordenfelt, S; Li, H; De Filippo, C; Pruefer, K; Sawyer,; Posth, C; Haak1, H; Hallgren, F; Fornander, E; Rohland, N; Delsate, D; Francken, M; Guinet, J; Wah, J; Ayodo, G; Babiker, H; Bailliet, G; Balanovska, E; Balanovsky, O; Barrantes, R; Bedoya, G; Ben Ami, H; Bene, J; Berrada, F; Bravi, C; Brisighelli, F; Busby, G; Cali, F; Churnosov, M; Cole, D; Corach, D; Damba, L; van Driem, G; Dryomov, S; Dugoujon, J; Fedorova, S; Gallego Romero, I; Gubina, M; Hammer, M; Henn, B; Hervig, T; Hodoglugi, U; Jha, A; Karachanak Yankova, S; Khusainova, R; Khusnutdinova, E; Kittles, R; T,; Klitz, W; Kucˇinskas, V; Kushniarevich, A; Laredj, L; Litvinov, S; Loukidis, T; Mahley, R; Melegh, B; Metspalu, E; Molina, J; Mountain, J; Na¨kka¨la¨ja¨rvi, K; Nesheva, D; Nyambo, T; Osipova, L; Parik, J; Platonov, F; Posukh, O; Romano, V; Rothhammer, F; Rudan, I; Ruizbakiev, R; Sahakyan, H; Sajantila, A; Salas, A; Starikovskaya, E; Tarekegn, A; Toncheva, D; Turdikulova, S; Uktveryte, I; Utevska, O; Vasquez, R; Villena, M; Voevoda, M; Winkler, C; Yepiskoposyan, L; Zalloua, P; Zemunik, T; Cooper,; Capelli, C; Thomas, M; Ruiz inares, A; Tishkoff, S; Singh, L; Thangaraj, K; Villems, R; Comas, D; Sukernik, R; Metspalu, M; Meyer, M; Eichler, E; Burger, J; Slatkin, M; Pa¨a¨bo, S; Kelso, J; Reich, D; Krause, J

doi:10.1038/nature13673

We sequenced the genomes of a 7,000-year-old farmer from Germany and eight 8,000-year-old hunter-gatherers fromLuxembourg and Sweden. We analysed these and other ancient genomes with 2,345 contemporaryhumansto show that most present-dayEuropeans derive from at least three highly differentiated populations:westEuropean hunter-gatherers,who contributed ancestry to all Europeans but not toNearEasterners; ancient north Eurasians related toUpper Palaeolithic Siberians, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunter-gatherer related ancestry.Wemodel these populations’ deep relationships and show that early European farmers had 44% ancestry from a ‘basal Eurasian’ population that split before the diversification of other non-African lineages.

Lazaridis, I., Patterson, P., Mittnik, A., Renaud, G., Mallick, S., Kirsanow, K., et al. (2014). Ancient human genomes suggest three ancestral populations for present-day Europeans. NATURE, 513(7518), 409-413.

Data di pubblicazione:	2014
Titolo:	Ancient human genomes suggest three ancestral populations for present-day Europeans
Autori:	Lazaridis,I Patterson,P Mittnik,A Renaud,G Mallick,S Kirsanow,K Sudmant,PH Schraiber,JG Castellano,S Lipson,M Berger,B Economou,C Bollongino,R Fu,Q Bos,KI Nordenfelt,S Li,H De Filippo,C Pruefer,K Sawyer Posth,C Haak1,H Hallgren,F Fornander,E Rohland,N Delsate,D Francken,M Guinet,JM Wah,J Ayodo,G Babiker,HA Bailliet,G Balanovska,E Balanovsky,O Barrantes,R Bedoya,G Ben Ami,H Bene,J Berrada,F Bravi,CM Brisighelli,F Busby,GBJ Cali,F Churnosov,M Cole,DEC Corach,D Damba,L van Driem,G Dryomov,S Dugoujon,JM Fedorova,SA Gallego Romero,I Gubina,M Hammer,M Henn,BM Hervig,T Hodoglugi,U Jha,AR Karachanak Yankova,S Khusainova,R Khusnutdinova,E Kittles, R:Kivisild T Klitz,W Kucˇinskas,V Kushniarevich,A Laredj,L Litvinov,S Loukidis,T Mahley,RW Melegh,B Metspalu,E Molina,J Mountain,J Na¨kka¨la¨ja¨rvi,K Nesheva,D Nyambo,T Osipova,L Parik,J Platonov,F Posukh,O ROMANO, Valentino Rothhammer,F Rudan,I Ruizbakiev,R Sahakyan,H Sajantila,A Salas,A Starikovskaya,EB Tarekegn,A Toncheva,D Turdikulova,S Uktveryte,I Utevska,O Vasquez,R Villena,M Voevoda,M Winkler,CA Yepiskoposyan,L Zalloua,P Zemunik,T Cooper Capelli,C Thomas,MG Ruiz inares,A Tishkoff,SA Singh,L Thangaraj,K Villems,R Comas,D Sukernik,R Metspalu,M Meyer,M Eichler,EE Burger,J Slatkin,M Pa¨a¨bo,S Kelso,J Reich,D Krause,J mostra contributor esterni nascondi contributor esterni
Citazione:	Lazaridis, I., Patterson, P., Mittnik, A., Renaud, G., Mallick, S., Kirsanow, K., et al. (2014). Ancient human genomes suggest three ancestral populations for present-day Europeans. NATURE, 513(7518), 409-413.
Rivista:	NATURE
Digital Object Identifier (DOI):	http://dx.doi.org/10.1038/nature13673
Abstract:	We sequenced the genomes of a 7,000-year-old farmer from Germany and eight 8,000-year-old hunter-gatherers fromLuxembourg and Sweden. We analysed these and other ancient genomes with 2,345 contemporaryhumansto show that most present-dayEuropeans derive from at least three highly differentiated populations:westEuropean hunter-gatherers,who contributed ancestry to all Europeans but not toNearEasterners; ancient north Eurasians related toUpper Palaeolithic Siberians, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunter-gatherer related ancestry.Wemodel these populations’ deep relationships and show that early European farmers had 44% ancestry from a ‘basal Eurasian’ population that split before the diversification of other non-African lineages.
Settore Scientifico Disciplinare:	Settore BIO/13 - Biologia Applicata
Appare nelle tipologie:	1.01 Articolo in rivista

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