Fifty-six young central obese patients were investigated to evaluate relationships between soluble E-selectin (sE-S), angiotensin-converting enzyme (ACE) gene polymorphism, left ventricular function and structure, and carotid morphology by determination of sE-S and ACE genotypes. Our results indicated that central obese subjects with concomitant higher levels of sE-S and ACE DD genotype may be characterized by early cardiovascular alterations and then considered a particular subset of subjects at higher risk of cardiovascular disease.
Licata, G., Di Chiara, T., Licata, A., Triolo, G., Argano, C., Pinto, A., et al. (2003). Relationship between circulating E-selectin, DD genotype of angiotensin-converting-enzyme, and cardiovascular damage in central obese subjects. METABOLISM, CLINICAL AND EXPERIMENTAL, 52(8), 999-1004 [10.1016/S0026-0495(03)00150-1].
Relationship between circulating E-selectin, DD genotype of angiotensin-converting-enzyme, and cardiovascular damage in central obese subjects
LICATA, Giuseppe;DI CHIARA, Tiziana;LICATA, Anna;TRIOLO, Giovanni;PINTO, Antonio;PARRINELLO, Gaspare;CORRAO, Salvatore;SCAGLIONE, Rosario
2003-01-01
Abstract
Fifty-six young central obese patients were investigated to evaluate relationships between soluble E-selectin (sE-S), angiotensin-converting enzyme (ACE) gene polymorphism, left ventricular function and structure, and carotid morphology by determination of sE-S and ACE genotypes. Our results indicated that central obese subjects with concomitant higher levels of sE-S and ACE DD genotype may be characterized by early cardiovascular alterations and then considered a particular subset of subjects at higher risk of cardiovascular disease.
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