This pilot study aimed to establish end-to-end stereotactic radiosurgery (SRS) sessions and evaluate the accuracy of the delivered doses using EPR/alanine and GAFChromic™ EBT3 films. Six Planning Treatment Volumes (PTVs), representing variations in tumor size, location, and proximity to Organs at Risk (OARs), were assessed using an anthropomorphic male head phantom irradiated with a TomoTherapy Hi-Art system (fraction of 10.5 Gy). Maximum deviations ranged from − 0.35 to 0.16 Gy, and − 0.35 to − 0.08 Gy, for alanine and films, respectively, even under complex spatial dose distribution (e.g., PTV6). Therefore, the findings demonstrated the reliability of both systems for precise SRS dosimetry.
Panzeca, S., De Farias Soares, A., Iacoviello, G., Cucchiara, T., Gallo, S., Romeo, M., et al. (2025). Dosimetric evaluation using EPR/alanine and radiochromic film detectors in end-to-end brain stereotactic radiosurgery sessions. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, 334(10), 7305-7317 [10.1007/s10967-025-10429-z].
Dosimetric evaluation using EPR/alanine and radiochromic film detectors in end-to-end brain stereotactic radiosurgery sessions
de Farias Soares A.
;Romeo M.;D'Oca M. C.;Marrale M.
2025-10-25
Abstract
This pilot study aimed to establish end-to-end stereotactic radiosurgery (SRS) sessions and evaluate the accuracy of the delivered doses using EPR/alanine and GAFChromic™ EBT3 films. Six Planning Treatment Volumes (PTVs), representing variations in tumor size, location, and proximity to Organs at Risk (OARs), were assessed using an anthropomorphic male head phantom irradiated with a TomoTherapy Hi-Art system (fraction of 10.5 Gy). Maximum deviations ranged from − 0.35 to 0.16 Gy, and − 0.35 to − 0.08 Gy, for alanine and films, respectively, even under complex spatial dose distribution (e.g., PTV6). Therefore, the findings demonstrated the reliability of both systems for precise SRS dosimetry.
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