Vitamin K is an essential fat soluble vitamin involved in the regulation of normal coagulation. However, growing evidence highlights that this molecule appears to be also implicated in the regulation of other important biological functions such as bone mineralization, calcium homeostasis, apoptosis, cell growth and signal transduction. In particular, many studies have focused their attention on the protective effects of vitamin K on bone tissue in the outlook of its use in the prevention and treatment of osteoporosis in post-menopausal women. The objective of the present paper is to review data of the literature regarding the metabolic effects of Vitamin K in bone tissue and its clinical role in the prevention and treatment of osteoporosis.

Giammanco, M., Di Majo, D., Leto, G., Flandina, C., Di Piazza, M., La Guardia, M. (2012). The Role of Vitamin K in Bone Remodeling and Osteoporosis. JOURNAL OF FOOD RESEARCH, 1(4), 106-123 [10.5539/jfr.v1n4p106].

The Role of Vitamin K in Bone Remodeling and Osteoporosis

GIAMMANCO, Marco;DI MAJO, Danila;LETO, Gaetano;FLANDINA, Carla;LA GUARDIA, Maurizio
2012-01-01

Abstract

Vitamin K is an essential fat soluble vitamin involved in the regulation of normal coagulation. However, growing evidence highlights that this molecule appears to be also implicated in the regulation of other important biological functions such as bone mineralization, calcium homeostasis, apoptosis, cell growth and signal transduction. In particular, many studies have focused their attention on the protective effects of vitamin K on bone tissue in the outlook of its use in the prevention and treatment of osteoporosis in post-menopausal women. The objective of the present paper is to review data of the literature regarding the metabolic effects of Vitamin K in bone tissue and its clinical role in the prevention and treatment of osteoporosis.
Settore BIO/09 - Fisiologia
http://dx.doi.org/10.5539/jfr.v1n4p106
Giammanco, M., Di Majo, D., Leto, G., Flandina, C., Di Piazza, M., La Guardia, M. (2012). The Role of Vitamin K in Bone Remodeling and Osteoporosis. JOURNAL OF FOOD RESEARCH, 1(4), 106-123 [10.5539/jfr.v1n4p106].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/66803
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