Toscana sandfly fever virus (TOSV) is an arthropod-borne virus transmitted to humans by sandfly vectors. It has been associated with human cases of meningitis and meningo-encephalitis mainly occurring during the warm season. We performed a retrospective serological study to evaluate TOSV circulation in Palermo, Sicily, and to compare TOSV seroprevalence in patients with neurological symptoms and in a control group of patients without neurological symptoms. When sera from 155 patients with and without neurological symptoms were evaluated, the rate of overall TOSV IgG reactivity was 17.4%. Patients with neurological symptoms showed a higher percentage of TOSV IgG positivity than control patients (25% versus 10.8%). TOSV exposure was confirmed by virus neutralization tests which also detected a Naples virus (SFNV) infection. TOSV should be considered as an etiologic agent in the differential diagnosis of fever and meningo-encephalitis in Sicily.
|Data di pubblicazione:||2012|
|Titolo:||Prevalence of Toscana sand fly virus antibodies in neurological patients and control subjects in Sicily|
|Citazione:||Colomba, C., Saporito, L., Ciufolini, M., Marchi, A., Rotolo, V., DE GRAZIA, S., et al. (2012). Prevalence of Toscana sand fly virus antibodies in neurological patients and control subjects in Sicily. NEW MICROBIOLOGICA, 35(2), 161-165.|
|Settore Scientifico Disciplinare:||Settore MED/07 - Microbiologia E Microbiologia Clinica|
Settore MED/17 - Malattie Infettive
|Appare nelle tipologie:||1.01 Articolo in rivista|