Introduction Despite the efforts directed towards augmenting dopaminergic function in Parkinson Disease (PD), there remains an unmet need to reduce in patients delayed time of motor fluctuations and diskynesia. Peroral administration of conventional medications do not resolve this problem and it may be necessary to use alternative delivery routes
De Caro, V., Scaturro, A.L., Giandalia, G., Siragusa, M.G., Sutera, F.M., Campisi, G., et al. (2012). Transbuccal delivery of l-dopa methyl ester: ex vivo permeation studies. In Proceedings of 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology.
Transbuccal delivery of l-dopa methyl ester: ex vivo permeation studies
DE CARO, Viviana;SCATURRO, Anna Lisa;GIANDALIA, Giulia;SIRAGUSA, Maria Gabriella;SUTERA, Flavia Maria;CAMPISI, Giuseppina;FLORENA, Ada Maria;GIANNOLA, Libero Italo
2012-01-01
Abstract
Introduction Despite the efforts directed towards augmenting dopaminergic function in Parkinson Disease (PD), there remains an unmet need to reduce in patients delayed time of motor fluctuations and diskynesia. Peroral administration of conventional medications do not resolve this problem and it may be necessary to use alternative delivery routes
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