Quetiapine is an atypical antipsychotic drug used to treat bipolar disorder, schizophrenia, and major depressive disorder. Although several studies describe the adverse effects of intoxication with Quetiapine, only a few report an extreme overdose without comedications that lead to a life threat. We present a case of a 75-year-old male who tried to attempt suicide by ingesting 28 g of Quetiapine. During the management in the emergency department, both serum and urine samples were collected, allowing a complete pharmacokinetic analysis to be conducted, from the admission to the discharge.
Elisabetta Bertol, Fabio Vaiano, Antonina Argo, Stefania Zerbo, Claudia Trignano, Simone Protani, et al. (2021). Overdose of Quetiapine—A Case Report with QT Prolongation. TOXICS, 9(393), 2-7 [10.3390/toxics9120339].
Overdose of Quetiapine—A Case Report with QT Prolongation
Antonina ArgoSecondo
Methodology
;Stefania Zerbo;
2021-12-07
Abstract
Quetiapine is an atypical antipsychotic drug used to treat bipolar disorder, schizophrenia, and major depressive disorder. Although several studies describe the adverse effects of intoxication with Quetiapine, only a few report an extreme overdose without comedications that lead to a life threat. We present a case of a 75-year-old male who tried to attempt suicide by ingesting 28 g of Quetiapine. During the management in the emergency department, both serum and urine samples were collected, allowing a complete pharmacokinetic analysis to be conducted, from the admission to the discharge.
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