The distribution of cholesterol plasma is regulated by complex interactions between genes and environmental factors. Mutations of PCSK9 gene seem to modulate the levels of LDLC. Mutations of PCSK9 gene with gain of function are associated to hypercholesterolemia and mutations with loss of function determine hypocholesterolemia.
Cefalu, A.B., Amato, S., Fertitta, E., Fayer, F., Valenti, V., Gueli, M.C., et al. (2007). The PCSK9 gene: a new gene controlling cholesterolemia. ACTA MEDICA MEDITERRANEA, 23(1), 11-14.
The PCSK9 gene: a new gene controlling cholesterolemia
Cefalu, ABPrimo
;Amato, S;Fertitta, E;Fayer, F;Valenti, V;Gueli, MC;Cusumano, G;Gulotta, P;Raffa, A;Doveri, T;Averna, MUltimo
2007-01-01
Abstract
The distribution of cholesterol plasma is regulated by complex interactions between genes and environmental factors. Mutations of PCSK9 gene seem to modulate the levels of LDLC. Mutations of PCSK9 gene with gain of function are associated to hypercholesterolemia and mutations with loss of function determine hypocholesterolemia.
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IL GENE PCSK9_UN NUOVO GENE IMPLICATO NEL CONTROLLO DELLACOLESTEROLEMIA.pdf
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