The distribution of cholesterol plasma is regulated by complex interactions between genes and environmental factors. Mutations of PCSK9 gene seem to modulate the levels of LDLC. Mutations of PCSK9 gene with gain of function are associated to hypercholesterolemia and mutations with loss of function determine hypocholesterolemia.

Cefalu, A.B., Amato, S., Fertitta, E., Fayer, F., Valenti, V., Gueli, M.C., et al. (2007). The PCSK9 gene: a new gene controlling cholesterolemia. ACTA MEDICA MEDITERRANEA, 23(1), 11-14.

The PCSK9 gene: a new gene controlling cholesterolemia

Cefalu, AB
Primo
;
Amato, S;Fertitta, E;Fayer, F;Valenti, V;Gueli, MC;Cusumano, G;Gulotta, P;Raffa, A;Doveri, T;Averna, M
Ultimo
2007

Abstract

The distribution of cholesterol plasma is regulated by complex interactions between genes and environmental factors. Mutations of PCSK9 gene seem to modulate the levels of LDLC. Mutations of PCSK9 gene with gain of function are associated to hypercholesterolemia and mutations with loss of function determine hypocholesterolemia.
Settore MED/09 - Medicina Interna
Cefalu, A.B., Amato, S., Fertitta, E., Fayer, F., Valenti, V., Gueli, M.C., et al. (2007). The PCSK9 gene: a new gene controlling cholesterolemia. ACTA MEDICA MEDITERRANEA, 23(1), 11-14.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10447/538015
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