The aim of the study is to evaluate the diagnostic performance of apparent diffusion coefficient (ADC) and apparent kurtosis coefficient (Kapp) for the characterization of prostate lesions on 1.5T MRI. This retrospective study included 34 patients with at least one lesion with PI-RADS score≥ 3. Performances of ADC and Kapp were evaluated using the Mann-Whitney U test and receiver operating characteristics curve (AUROC). Lesions with Gleason score≥6 had significantly lower Kapp compared to benign lesions (p=0.025). The ADC-ratio was the only significantly different parameter between GS≥7 and GS=6 lesions (p=0.039). Kapp showed the largest AUROC for the diagnosis of GS≥6 prostate cancers (AUROC: 0.741, p=0.025), while the largest AUROC for the diagnosis of GS≥7 prostate cancers was achieved by the ADC-ratio (AUROC: 0.709, p=0.039). While Kapp demonstrated no significant benefit in characterization of prostate cancers compared to ADC, it could be helpful to distinguish benign lesions from prostate cancers.
Gabriele Busè, R.C. (2020). PERFORMANCE OF DIFFUSION KURTOSIS IMAGING FOR CHARACTERIZATION OF PROSTATE LESIONS USING 1.5T MAGNETIC RESONANCE IMAGING SCANNER. EUROMEDITERRANEAN BIOMEDICAL JOURNAL, 15(46), 197-202 [10.3269/1970-5492.2020.15.46].
PERFORMANCE OF DIFFUSION KURTOSIS IMAGING FOR CHARACTERIZATION OF PROSTATE LESIONS USING 1.5T MAGNETIC RESONANCE IMAGING SCANNER
Gabriele Busè;Roberto Cannella;Alberto Bruno;Claudio Leto;Giuseppe Cutaia
;Leonardo Salvaggio;Dario Giambelluca;Marcella Ferraro;Federica Vernuccio;Giorgio Collura;Cesare Gagliardo;Maurizio Marrale;Massimo Midiri;Massimo Galia;
2020-01-01
Abstract
The aim of the study is to evaluate the diagnostic performance of apparent diffusion coefficient (ADC) and apparent kurtosis coefficient (Kapp) for the characterization of prostate lesions on 1.5T MRI. This retrospective study included 34 patients with at least one lesion with PI-RADS score≥ 3. Performances of ADC and Kapp were evaluated using the Mann-Whitney U test and receiver operating characteristics curve (AUROC). Lesions with Gleason score≥6 had significantly lower Kapp compared to benign lesions (p=0.025). The ADC-ratio was the only significantly different parameter between GS≥7 and GS=6 lesions (p=0.039). Kapp showed the largest AUROC for the diagnosis of GS≥6 prostate cancers (AUROC: 0.741, p=0.025), while the largest AUROC for the diagnosis of GS≥7 prostate cancers was achieved by the ADC-ratio (AUROC: 0.709, p=0.039). While Kapp demonstrated no significant benefit in characterization of prostate cancers compared to ADC, it could be helpful to distinguish benign lesions from prostate cancers.File | Dimensione | Formato | |
---|---|---|---|
2020 Performance of diffusion kurtosis imaging for characterization of prostate lesions using 1.5T magnetic resonance imaging scanner.pdf
accesso aperto
Descrizione: Articolo pubblicato
Tipologia:
Versione Editoriale
Dimensione
608.4 kB
Formato
Adobe PDF
|
608.4 kB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.