Although coffee is largely consumed by adults in Western countries, controversy exists about its impact on the cardiovascular system. We recently demonstrated that caffeinated and decaffeinated espresso coffee have different acute effects on endothelial function in healthy subjects, measured using flow-mediated dilation (FMD) of the brachial artery. In this study, we measured the anti-oxidant capacity of two coffee substances in terms of free stable radical 2,2-diphenyl-1-picryl-hydrazyl 50% inhibition (I50 DPPH). The caffeinated coffee had a slightly higher anti-oxidant capacity than decaffeinated espresso coffee (I50 DPPH: 1.13±0.02 vs 1.30±0.03 ml; Po0.001). We suggest that the unfavourable effects observed after caffeinated coffee ingestion are due to caffeine and that the antioxidant activity is responsible for the increased FMD observed after decaffeinated coffee ingestion. Further clinical and epidemiological studies are needed to understand the chronic effects of coffee consumption on health.

Buscemi, S., Batsis, J.A., Arcoleo, G., Verga, S. (2010). Coffee and endothelial function: a battle between caffeine and antioxidants ?. EUROPEAN JOURNAL OF CLINICAL NUTRITION.

Coffee and endothelial function: a battle between caffeine and antioxidants ?

BUSCEMI, Silvio;ARCOLEO, Gioacchina;VERGA, Salvatore
2010-01-01

Abstract

Although coffee is largely consumed by adults in Western countries, controversy exists about its impact on the cardiovascular system. We recently demonstrated that caffeinated and decaffeinated espresso coffee have different acute effects on endothelial function in healthy subjects, measured using flow-mediated dilation (FMD) of the brachial artery. In this study, we measured the anti-oxidant capacity of two coffee substances in terms of free stable radical 2,2-diphenyl-1-picryl-hydrazyl 50% inhibition (I50 DPPH). The caffeinated coffee had a slightly higher anti-oxidant capacity than decaffeinated espresso coffee (I50 DPPH: 1.13±0.02 vs 1.30±0.03 ml; Po0.001). We suggest that the unfavourable effects observed after caffeinated coffee ingestion are due to caffeine and that the antioxidant activity is responsible for the increased FMD observed after decaffeinated coffee ingestion. Further clinical and epidemiological studies are needed to understand the chronic effects of coffee consumption on health.
2010
Buscemi, S., Batsis, J.A., Arcoleo, G., Verga, S. (2010). Coffee and endothelial function: a battle between caffeine and antioxidants ?. EUROPEAN JOURNAL OF CLINICAL NUTRITION.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/50529
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