Arterial hypertension is a significant cause of end-stage renal failure; effective treatment of hypertensive patients reduces the rate of progression of this disorder. β-Blockers, particularly nonselective agents, are associated with deterioration of renal function in patients with chronic renal failure. Previous studies on the interaction of the β 1-selective adrenergic antagonist bisoprolol with kidney function have been performed only acutely and over the short term. This study was designed to evaluate the antihypertensive efficacy and effects on renal hemodynamics and function of bisoprolol during medium-term (6 mo) treatment of patients with mild to moderate essential hypertension.
PATERNA S, GPARRINELLO, PDI PASQUALE, D TORRES, GLA ROCCA, RANTONA, et al. (2007). Medium-Term Effects of Bisoprolol Administration on Renal Hemodynamics and Function in Mild to Moderate Essential Hypertension. ADVANCES IN THERAPY, 24(6), 1260-1270 [10.1007/BF02877772].
Medium-Term Effects of Bisoprolol Administration on Renal Hemodynamics and Function in Mild to Moderate Essential Hypertension
PATERNA, Salvatore;PARRINELLO, Gaspare;TORRES, Daniele;ANTONA, Roberta;FORNACIARI, Ersilia;TARANTINO, Antonina;FASULLO, Silvio;LICATA, Giuseppe
2007-01-01
Abstract
Arterial hypertension is a significant cause of end-stage renal failure; effective treatment of hypertensive patients reduces the rate of progression of this disorder. β-Blockers, particularly nonselective agents, are associated with deterioration of renal function in patients with chronic renal failure. Previous studies on the interaction of the β 1-selective adrenergic antagonist bisoprolol with kidney function have been performed only acutely and over the short term. This study was designed to evaluate the antihypertensive efficacy and effects on renal hemodynamics and function of bisoprolol during medium-term (6 mo) treatment of patients with mild to moderate essential hypertension.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.