The S-100 family of calcium-binding proteins includes about 20 members of low molecular weight characterized by two consecutive EF hands domains. They make interactions with cellular target proteins in a calcium-dependent manner; therefore they are thought to regulate a variety of physiological functions, such as cell proliferation, signal transduction, cell adhesion, motility as well as cancer metastasis.
PUCCI, I., CANCEMI, P., DI CARA, G., ALBANESE, N.N., MARABETI, M.R., COSTANTINI, F., et al. (2009). S-100 calcium binding proteins as potential markers for breast cancer metastasis.. In XXVIII Italian Society for the Study of Connective Tissues (SISC) Meeting, Pavia, Italy, 6-7 November 2008',Connective Tissue Research,50:2,65—97, 2009 (pp.90-91). London : Informa Healthcare USA, Inc. [10.1080/03008200802683187].
S-100 calcium binding proteins as potential markers for breast cancer metastasis.
PUCCI, Ida;CANCEMI, Patrizia;DI CARA, Gianluca;ALBANESE, Nadia Ninfa;MARABETI, Maria Rita;COSTANTINI, Francesca;MUSSO, Rosa;MARRAZZO, Antonio;
2009-01-01
Abstract
The S-100 family of calcium-binding proteins includes about 20 members of low molecular weight characterized by two consecutive EF hands domains. They make interactions with cellular target proteins in a calcium-dependent manner; therefore they are thought to regulate a variety of physiological functions, such as cell proliferation, signal transduction, cell adhesion, motility as well as cancer metastasis.
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