Hodgkin's lymphoma is a very common haematological neoplasm with high possibilities of response to treatment. On the other hand, therapies are often responsible for clinically relevant complications. Among these is osteonecrosis, generally determined by the high dosages of corticosteroids included in the chemotherapeutic protocols, which lead to bone ischemia through multifactorial mechanisms such as hypercoagulability and increase of intraosseous pressure due to hyperplasia of the adipose component. We report the case of a 29-year-old man with resistant Hodgkin's lymphoma undergoing chemotherapy which determined the appearance of multifocal osteonecrosis detected by Magnetic Resonance whole body.
Albano, D., Patti, C., La Grutta, L., Grassedonio, E., Lo Re, G., Lagalla, R., et al. (2016). Diagnosi di osteonecrosi mediante WB-MRI in paziente con Linfoma di Hodgkin resistente trattato con BEACOPP: Case Report. IL GIORNALE ITALIANO DI RADIOLOGIA MEDICA, 1(3), 165-168 [10.17376/girm_3-1-01022016-18].
Diagnosi di osteonecrosi mediante WB-MRI in paziente con Linfoma di Hodgkin resistente trattato con BEACOPP: Case Report.
ALBANO, Domenico;LA GRUTTA, Ludovico;GRASSEDONIO, Emanuele;LO RE, Giuseppe;LAGALLA, Roberto;MIDIRI, Massimo;GALIA, Massimo
2016-01-01
Abstract
Hodgkin's lymphoma is a very common haematological neoplasm with high possibilities of response to treatment. On the other hand, therapies are often responsible for clinically relevant complications. Among these is osteonecrosis, generally determined by the high dosages of corticosteroids included in the chemotherapeutic protocols, which lead to bone ischemia through multifactorial mechanisms such as hypercoagulability and increase of intraosseous pressure due to hyperplasia of the adipose component. We report the case of a 29-year-old man with resistant Hodgkin's lymphoma undergoing chemotherapy which determined the appearance of multifocal osteonecrosis detected by Magnetic Resonance whole body.
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