Visceral leishmaniasis due to Leishmania infantum is a vector-borne zoonotic disease transmitted by sand fly bites endemic in rural or periurban areas of the Mediterranean basin. Pregnancy is accompanied by changes in immune response, mainly a decrease in cellular immunity and a proportional increase in humoral immunity. These physiological events result in increased risk of infection by pathogens whose immunity is based on a T-helper 1 predominant response. We describe a case of visceral leishmaniasis and pulmonary tuberculosis diagnosed in a post-partum woman four days after delivery. The diagnosis of leishmaniasis should be considered in pregnant women with fever and haematologic abnormalities in endemic regions or if a history of exposure in endemic areas is reported.
Colomba, C., Adamoli, L., Trizzino, M., Siracusa, L., Bonura, S., Tolomeo, M., et al. (2015). A case of visceral leishmaniasis and pulmonary tuberculosis in a post-partum woman. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 33, e5-e6 [10.1016/j.ijid.2014.12.020].
A case of visceral leishmaniasis and pulmonary tuberculosis in a post-partum woman
COLOMBA, Claudia
;ADAMOLI, Lucia;TRIZZINO, Marcello;SIRACUSA, Lucia;BONURA, Silvia;CAJOZZO, Massimo;GIAMMANCO, Giovanni
2015-01-01
Abstract
Visceral leishmaniasis due to Leishmania infantum is a vector-borne zoonotic disease transmitted by sand fly bites endemic in rural or periurban areas of the Mediterranean basin. Pregnancy is accompanied by changes in immune response, mainly a decrease in cellular immunity and a proportional increase in humoral immunity. These physiological events result in increased risk of infection by pathogens whose immunity is based on a T-helper 1 predominant response. We describe a case of visceral leishmaniasis and pulmonary tuberculosis diagnosed in a post-partum woman four days after delivery. The diagnosis of leishmaniasis should be considered in pregnant women with fever and haematologic abnormalities in endemic regions or if a history of exposure in endemic areas is reported.File | Dimensione | Formato | |
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