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EnglishAbstract Neurofibromas are considered one of the hallmark signs of neurofibromatosis type 1(NF1). Diffuse plexiform neurofibroma is a congenital NF1-associated tumor, characterized by overgrowth and interference with function of the affected area. The rich vascular plexus associated with neurofibromas, together with their infiltrative pattern, makes them difficult to eradicate. Complications of neurofibromas are rare but include malignant transformation and potentially lifethreatening hemorrhages. The use of the term “giant” to define a neurofibroma is controversial because there is no clear consensus and descriptions are limited to few case reports. We report a case of a large dorsal diffuse plexiform neurofibroma responsible for significant worsening of a patient’s quality of life. These features make us believe that the mass can be defined as “giant.” Comprehensive perioperative management, including arterial embolization of the feeding vessels and stabilization of the patient’s conditions, is required to perform a safe surgical procedure in such a complicated case.
D'Arpa, S., Tuttolomondo, A., Melloni, C., Cordova, A., & Moschella, F. (2014). Management of large dorsal diffuse plexiform neurofibroma. EUROPEAN JOURNAL OF PLASTIC SURGERY, 37, 349-352.
| Data di pubblicazione: | 2014 |
| Titolo: | Management of large dorsal diffuse plexiform neurofibroma |
| Autori: | |
| Citazione: | D'Arpa, S., Tuttolomondo, A., Melloni, C., Cordova, A., & Moschella, F. (2014). Management of large dorsal diffuse plexiform neurofibroma. EUROPEAN JOURNAL OF PLASTIC SURGERY, 37, 349-352. |
| Rivista: | |
| Digital Object Identifier (DOI): | http://dx.doi.org/DOI 10.1007/s00238-014-0953-5 |
| Abstract: | Abstract Neurofibromas are considered one of the hallmark signs of neurofibromatosis type 1(NF1). Diffuse plexiform neurofibroma is a congenital NF1-associated tumor, characterized by overgrowth and interference with function of the affected area. The rich vascular plexus associated with neurofibromas, together with their infiltrative pattern, makes them difficult to eradicate. Complications of neurofibromas are rare but include malignant transformation and potentially lifethreatening hemorrhages. The use of the term “giant” to define a neurofibroma is controversial because there is no clear consensus and descriptions are limited to few case reports. We report a case of a large dorsal diffuse plexiform neurofibroma responsible for significant worsening of a patient’s quality of life. These features make us believe that the mass can be defined as “giant.” Comprehensive perioperative management, including arterial embolization of the feeding vessels and stabilization of the patient’s conditions, is required to perform a safe surgical procedure in such a complicated case. |
| Settore Scientifico Disciplinare: | Settore MED/19 - Chirurgia Plastica |
| Appare nelle tipologie: | 1.01 Articolo in rivista |
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