The analysis of the aerial parts of Bonannia graeca led to the isolation and characterization of polar geranylated flavonoids (6 and 7). The structure elucidation was performed by extensive spectroscopic methods (1D and 2D NMR) and comparison with literature data. All natural flavonoids isolated from B. graeca (1-7) and some synthetic derivatives (8-11) were tested for cytotoxic activity against four human tumor cell lines. Preliminary structure-activity relationship correlations are discussed
Rosselli, S., Bruno, M., Maggio, A., Raccuglia, R.A., Safder, M., Lai, C.Y., et al. (2011). Cytotoxic geranylflavonoids from Bonannia graeca. PHYTOCHEMISTRY, 72(9), 942-945 [10.1016/j.phytochem.2011.03.005].
Cytotoxic geranylflavonoids from Bonannia graeca
ROSSELLI, Sergio;BRUNO, Maurizio;MAGGIO, Antonella Maria;RACCUGLIA, Rosa Angela;
2011-01-01
Abstract
The analysis of the aerial parts of Bonannia graeca led to the isolation and characterization of polar geranylated flavonoids (6 and 7). The structure elucidation was performed by extensive spectroscopic methods (1D and 2D NMR) and comparison with literature data. All natural flavonoids isolated from B. graeca (1-7) and some synthetic derivatives (8-11) were tested for cytotoxic activity against four human tumor cell lines. Preliminary structure-activity relationship correlations are discussed
| File | Dimensione | Formato | |
|---|---|---|---|
|
paper 220.pdf
Solo gestori archvio
Descrizione: Articolo principale
Dimensione
206.84 kB
Formato
Adobe PDF
|
206.84 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
