A literature survey of the chemistry of fluorinated oxadiazoles and thiadiazoles is presented. The core part on synthetic procedures is given by type of heterocycle and includes recent developments up to the end of 2012. Reactivity is discussed when induced by the presence of the fluorinated moiety. Selected examples of bioactive compounds and applications are illustrated.
Pace, A., Palumbo Piccionello, A., Pibiri, I., Buscemi, S., Vivona, N. (2014). Synthesis, Reactivity, Biological Activity and Applications of Fluorinated Oxadiazoles and Thiadiazoles. In Fluorine in Heterocyclic chemistry-Volume 1 (pp. 369-417). Springer International Publishing [10.1007/978-3-319-04346-3_9].
Synthesis, Reactivity, Biological Activity and Applications of Fluorinated Oxadiazoles and Thiadiazoles
PACE, Andrea;PALUMBO PICCIONELLO, Antonio;PIBIRI, Ivana;BUSCEMI, Silvestre;VIVONA, Nicolo'
2014-01-01
Abstract
A literature survey of the chemistry of fluorinated oxadiazoles and thiadiazoles is presented. The core part on synthetic procedures is given by type of heterocycle and includes recent developments up to the end of 2012. Reactivity is discussed when induced by the presence of the fluorinated moiety. Selected examples of bioactive compounds and applications are illustrated.
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