Acinetobacter baumannii has emerged as one of the most challenging healthcare-related pathogens and its occurrence has increased worldwide, especially in patients admitted to intensive care units. A. baumannii isolates are frequently resistant to multiple antimicrobial agents and there are recent reports of isolates resistant to virtually all clinically relevant drugs. In the present study, the in vitro activities of tigecycline, minocycline and doxycycline against 67 MDR-AB isolates recovered from 29 burn and 38 non-burn Iranian patients hospitalised in Tehran and Tabriz, respectively, were studied. Tigecycline and minocycline may be still considered effective therapeutic options for MDR-AB infections. However, ongoing monitoring of A. baumannii susceptibility to these antibiotics is required.

Pajand, O., Hojabri, Z., Nahaei, M.R., Hajibonabi, F., Pirzadeh, T., Aghazadeh, M., et al. (2014). In vitro activities of tetracyclines against different clones of multidrug-resistant Acinetobacter baumannii isolates from two Iranian hospitals. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 43(5), 476-478 [10.1016/j.ijantimicag.2014.02.001].

In vitro activities of tetracyclines against different clones of multidrug-resistant Acinetobacter baumannii isolates from two Iranian hospitals.

FASCIANA, Teresa Maria Assunta;BONURA, Celestino;MAMMINA, Caterina
2014-01-01

Abstract

Acinetobacter baumannii has emerged as one of the most challenging healthcare-related pathogens and its occurrence has increased worldwide, especially in patients admitted to intensive care units. A. baumannii isolates are frequently resistant to multiple antimicrobial agents and there are recent reports of isolates resistant to virtually all clinically relevant drugs. In the present study, the in vitro activities of tigecycline, minocycline and doxycycline against 67 MDR-AB isolates recovered from 29 burn and 38 non-burn Iranian patients hospitalised in Tehran and Tabriz, respectively, were studied. Tigecycline and minocycline may be still considered effective therapeutic options for MDR-AB infections. However, ongoing monitoring of A. baumannii susceptibility to these antibiotics is required.
Settore MED/42 - Igiene Generale E Applicata
Settore MED/07 - Microbiologia E Microbiologia Clinica
Pajand, O., Hojabri, Z., Nahaei, M.R., Hajibonabi, F., Pirzadeh, T., Aghazadeh, M., et al. (2014). In vitro activities of tetracyclines against different clones of multidrug-resistant Acinetobacter baumannii isolates from two Iranian hospitals. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 43(5), 476-478 [10.1016/j.ijantimicag.2014.02.001].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/96805
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