clinical evidence suggest that arthritis is one of the complications of inflammatori bowel disease (IBD) of which the etiological causes are still not completely understood. Among the possible explanations the most probable theory is poor regulation of the intestinal immune system, which causes a cross-like immune reactivity against the resident micro flora. Arthritis is these subjects involves different joints and is asymmetric, with greater involvement of the large joints of the lower limbs. Joints may also be involved with the spinal forms of sacroileitis and ankilosing spondylitis. This clinical evidence explains the existence of Lesnioski-Crohn's disease, a variant of IBD in which patients have bone joint problems that may also be the primary manifestations of the disease.

Tomasello, G., D'Arienzo, M., Lo Monte, A.I., Margiotta, G., D'Arienzo, A., Damiani, P., et al. (2013). HEAT SHOCK PROTEINS AND AUTOIMMUNE SYSTEM ACTIVATION IN IBD: ARTICULAR MANIFESTATIONS AND THE EPIDEMIOLOGICAL FREQUENCY IN ORTHPEDICS. ACTA MEDICA MEDITERRANEA, 29(29), 311-315.

HEAT SHOCK PROTEINS AND AUTOIMMUNE SYSTEM ACTIVATION IN IBD: ARTICULAR MANIFESTATIONS AND THE EPIDEMIOLOGICAL FREQUENCY IN ORTHPEDICS

TOMASELLO, Giovanni;D'ARIENZO, Michele;LO MONTE, Attilio Ignazio;MARGIOTTA, Giuseppe;D'ARIENZO, Antonio;SANFILIPPO, Antonino
2013-01-01

Abstract

clinical evidence suggest that arthritis is one of the complications of inflammatori bowel disease (IBD) of which the etiological causes are still not completely understood. Among the possible explanations the most probable theory is poor regulation of the intestinal immune system, which causes a cross-like immune reactivity against the resident micro flora. Arthritis is these subjects involves different joints and is asymmetric, with greater involvement of the large joints of the lower limbs. Joints may also be involved with the spinal forms of sacroileitis and ankilosing spondylitis. This clinical evidence explains the existence of Lesnioski-Crohn's disease, a variant of IBD in which patients have bone joint problems that may also be the primary manifestations of the disease.
Settore MED/18 - Chirurgia Generale
Settore MED/09 - Medicina Interna
Settore MED/33 - Malattie Apparato Locomotore
Tomasello, G., D'Arienzo, M., Lo Monte, A.I., Margiotta, G., D'Arienzo, A., Damiani, P., et al. (2013). HEAT SHOCK PROTEINS AND AUTOIMMUNE SYSTEM ACTIVATION IN IBD: ARTICULAR MANIFESTATIONS AND THE EPIDEMIOLOGICAL FREQUENCY IN ORTHPEDICS. ACTA MEDICA MEDITERRANEA, 29(29), 311-315.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/76942
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