The drugs available for inflammatory bowel disease are aminosalicylates, antibiotics, steroids, immunosuppressors and biologics. The effectiveness of these drugs has been evaluated in many randomized clinical trials, mainly versus placebo. Few studies have been conducted comparing the different drugs among themselves, owing to the methodological problems raised by comparative trials, such as sample size and blindness. This review focuses mainly on the randomized clinical trials that have compared different treatments. Of course comparisons are mainly between drugs used in a particular setting (mild, moderate and severe disease). However, on many occasions there is no homogeneity in these clinical settings, and therefore the results are difficult to interpret

Renna s, Orlando a, & Cottone M (2013). Comparing medical treatment in Crohn's disease. JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH, 2(2), 135-149.

Comparing medical treatment in Crohn's disease

COTTONE, Mario
2013

Abstract

The drugs available for inflammatory bowel disease are aminosalicylates, antibiotics, steroids, immunosuppressors and biologics. The effectiveness of these drugs has been evaluated in many randomized clinical trials, mainly versus placebo. Few studies have been conducted comparing the different drugs among themselves, owing to the methodological problems raised by comparative trials, such as sample size and blindness. This review focuses mainly on the randomized clinical trials that have compared different treatments. Of course comparisons are mainly between drugs used in a particular setting (mild, moderate and severe disease). However, on many occasions there is no homogeneity in these clinical settings, and therefore the results are difficult to interpret
Settore MED/09 - Medicina Interna
Renna s, Orlando a, & Cottone M (2013). Comparing medical treatment in Crohn's disease. JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH, 2(2), 135-149.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10447/74789
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