Low high-density lipoprotein (HDL) levels are major predictors of cardiovascular (CV) events, even in patients on statin treatment with low-density lipoprotein (LDL) at target. In animal models HDLs protect LDL from oxidation and blunt platelet activation. Our study aimed to examine whether HDL levels are related to in vivo oxidative stress and platelet activation, as determinants of atherothrombosis.
Vazzana, N., Ganci, A., Cefalù, A., Lattanzio, S., Noto, D., Santoro, N., et al. (2013). Enhanced Lipid Peroxidation and Platelet Activation as Potential Contributors to Increased Cardiovascular Risk in the Low-HDL Phenotype. JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE, 2(2) [10.1161/JAHA.113.000063].
Enhanced Lipid Peroxidation and Platelet Activation as Potential Contributors to Increased Cardiovascular Risk in the Low-HDL Phenotype
CEFALU', Angelo Baldassare;NOTO, Davide;AVERNA, Maurizio;
2013-01-01
Abstract
Low high-density lipoprotein (HDL) levels are major predictors of cardiovascular (CV) events, even in patients on statin treatment with low-density lipoprotein (LDL) at target. In animal models HDLs protect LDL from oxidation and blunt platelet activation. Our study aimed to examine whether HDL levels are related to in vivo oxidative stress and platelet activation, as determinants of atherothrombosis.
| File | Dimensione | Formato | |
|---|---|---|---|
|
Enhanced Lipid Peroxidation and Platelet Activation as Potential.pdf
accesso aperto
Descrizione: Articolo principale
Dimensione
949.56 kB
Formato
Adobe PDF
|
949.56 kB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
