Low high-density lipoprotein (HDL) levels are major predictors of cardiovascular (CV) events, even in patients on statin treatment with low-density lipoprotein (LDL) at target. In animal models HDLs protect LDL from oxidation and blunt platelet activation. Our study aimed to examine whether HDL levels are related to in vivo oxidative stress and platelet activation, as determinants of atherothrombosis.

Vazzana, N., Ganci, A., Cefalù, A., Lattanzio, S., Noto, D., Santoro, N., et al. (2013). Enhanced Lipid Peroxidation and Platelet Activation as Potential Contributors to Increased Cardiovascular Risk in the Low-HDL Phenotype. JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE, 2(2) [10.1161/JAHA.113.000063].

Enhanced Lipid Peroxidation and Platelet Activation as Potential Contributors to Increased Cardiovascular Risk in the Low-HDL Phenotype

CEFALU', Angelo Baldassare;NOTO, Davide;AVERNA, Maurizio;
2013

Abstract

Low high-density lipoprotein (HDL) levels are major predictors of cardiovascular (CV) events, even in patients on statin treatment with low-density lipoprotein (LDL) at target. In animal models HDLs protect LDL from oxidation and blunt platelet activation. Our study aimed to examine whether HDL levels are related to in vivo oxidative stress and platelet activation, as determinants of atherothrombosis.
Settore MED/09 - Medicina Interna
Vazzana, N., Ganci, A., Cefalù, A., Lattanzio, S., Noto, D., Santoro, N., et al. (2013). Enhanced Lipid Peroxidation and Platelet Activation as Potential Contributors to Increased Cardiovascular Risk in the Low-HDL Phenotype. JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE, 2(2) [10.1161/JAHA.113.000063].
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10447/73835
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