An abdominal aortic aneurysm (AAA) refers to a localized dilation or bulging of the abdominal aorta, the largest artery in the human body, affecting all three layers of the arterial wall. This condition occurs when the structural integrity of the aortic wall is compromised, leading to progressive weakening and subsequent enlargement of the vessel. AAA are frequently asymptomatic until they reach a substantial diameter or undergo rupture, the latter of which may result in life-threatening internal bleeding. The probability of rupture escalates with increasing aneurysm size, highlighting the importance of early detection and vigilant monitoring. The incidence of AAA is influenced by several demographic and clinical factors. Advancing age and the male sex are significant determinants, with the condition predominantly affecting men over the age of 65 years of age. Tobacco use represents a major modifiable risk factor, substantially elevating the likelihood of aneurysm development. A positive family history further predisposes individuals to AAA, indicating a hereditary component to disease susceptibility. Additional contributory factors include systemic hypertension, atherosclerotic disease, and various genetic predispositions, all of which play a role in the pathogenesis of aneurysmal degeneration
Bruno, S., Zammito, A., Monteleone, S., Tozzi, M., Pecoraro, F., Mirabella, D. (2025). The evolution of anatomical classification of abdominal aortic aneurysms. In Maurizio Taurino (a cura di), Abdominal Aortic Aneurysms: Anatomy, Pathophysiology, and Advanced Treatment (pp. 3-13). EDIZIONI MINERVA MEDICA S.p.A..
The evolution of anatomical classification of abdominal aortic aneurysms
Felice Pecoraro;
2025-01-01
Abstract
An abdominal aortic aneurysm (AAA) refers to a localized dilation or bulging of the abdominal aorta, the largest artery in the human body, affecting all three layers of the arterial wall. This condition occurs when the structural integrity of the aortic wall is compromised, leading to progressive weakening and subsequent enlargement of the vessel. AAA are frequently asymptomatic until they reach a substantial diameter or undergo rupture, the latter of which may result in life-threatening internal bleeding. The probability of rupture escalates with increasing aneurysm size, highlighting the importance of early detection and vigilant monitoring. The incidence of AAA is influenced by several demographic and clinical factors. Advancing age and the male sex are significant determinants, with the condition predominantly affecting men over the age of 65 years of age. Tobacco use represents a major modifiable risk factor, substantially elevating the likelihood of aneurysm development. A positive family history further predisposes individuals to AAA, indicating a hereditary component to disease susceptibility. Additional contributory factors include systemic hypertension, atherosclerotic disease, and various genetic predispositions, all of which play a role in the pathogenesis of aneurysmal degeneration| File | Dimensione | Formato | |
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