A Rare Case of Sterile Retrostyloid Abscess in a Patient With Crohn’s Disease: Diagnostic and Therapeutic Insights

Introduction: Aseptic abscess syndrome is a rare inflammatory disorder of unclear etiology, characterized by sterile lesions densely infiltrated by polymorphonuclear neutrophils. Its frequently associated with inflammatory bowel disease, which includes chronic gastrointestinal disorders such as Crohn’s disease and ulcerative colitis, often accompanied by both intestinal and extraintestinal manifestations. Extraintestinal involvement may include musculoskeletal, cutaneous, ocular, oral, and hepatobiliary systems. Although uncommon, aseptic abscess syndrome can precede the onset of inflammatory bowel disease or occur during its course. Case Report: A 44-year-old woman with Crohn’s disease receiving corticosteroid therapy is presented with abdominal pain, diarrhea, rectal bleeding, and a painful right lateral cervical swelling with trismus. Contrast-enhanced computed tomography revealed a right retrostyloid abscess. Surgical drainage, combined with antibiotics and corticosteroids, led to clinical resolution. Cultures were negative, confirming the diagnosis of aseptic abscess. Conclusion: Retrostyloid abscesses are extremely rare and poorly documented. In patients with inflammatory bowel disease presenting with deep neck abscesses, aseptic abscess syndrome should be considered, as early recognition and multidisciplinary management are essential to prevent serious complications.