: Diagnostic algorithms for syphilis are based on serology. However, with the advent of immunosuppressive therapies, these algorithms may fail. We report a case of an individual with multiple sclerosis on treatment with ofatumumab and secondary syphilis with visual and auditory systems involvement and persistent negative treponemal and nontreponemal tests.
Pipitò L., Ganci I., Cicero A., Medaglia A.A., D'Avenia S., Mandalà E., et al. (2024). A Case of Syphilis With Ocular Involvement: Persistent Negative Serology in a Patient With Multiple Sclerosis. OPEN FORUM INFECTIOUS DISEASES, 11(10), 1-5 [10.1093/ofid/ofae563].
A Case of Syphilis With Ocular Involvement: Persistent Negative Serology in a Patient With Multiple Sclerosis
Medaglia A. A.;D'Avenia S.;Di Carlo P.;Cascio A.
2024-01-01
Abstract
: Diagnostic algorithms for syphilis are based on serology. However, with the advent of immunosuppressive therapies, these algorithms may fail. We report a case of an individual with multiple sclerosis on treatment with ofatumumab and secondary syphilis with visual and auditory systems involvement and persistent negative treponemal and nontreponemal tests.
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