D-Glucosamine markedly inhibits thymidine incorporation into the TCA-insoluble fraction and thymidine kinase activity in HeLa cells. Both the inhibitory effects are also observed in isolated retinas of chick embryos. In this case the inhibitory effects are age-dependent and the magnitude of the responses decreases with embryonic development. In addition the time of exposure to D-glucosamine which is necessary to reveal the inhibitory effect on thymidine kinase increases with the age of the embryos.

TESORIERE, G., TESORIERE, L., VENTO, R., GIULIANO, M., & CANTORO, G. (1984). The inhibitory effect of D-glucosamine on thymidine kinase in chick embryo retinas and HeLa cells. EXPERIENTIA, 40(7), 705-707 [10.1007/BF01949733].

The inhibitory effect of D-glucosamine on thymidine kinase in chick embryo retinas and HeLa cells

TESORIERE, Luisa;VENTO, Renza;GIULIANO, Michela;
1984

Abstract

D-Glucosamine markedly inhibits thymidine incorporation into the TCA-insoluble fraction and thymidine kinase activity in HeLa cells. Both the inhibitory effects are also observed in isolated retinas of chick embryos. In this case the inhibitory effects are age-dependent and the magnitude of the responses decreases with embryonic development. In addition the time of exposure to D-glucosamine which is necessary to reveal the inhibitory effect on thymidine kinase increases with the age of the embryos.
Settore BIO/10 - Biochimica
TESORIERE, G., TESORIERE, L., VENTO, R., GIULIANO, M., & CANTORO, G. (1984). The inhibitory effect of D-glucosamine on thymidine kinase in chick embryo retinas and HeLa cells. EXPERIENTIA, 40(7), 705-707 [10.1007/BF01949733].
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10447/65956
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