The inhibitory effect of D-glucosamine on thymidine kinase in chick embryo retinas and HeLa cells

Tesoriere, G; Tesoriere, L; Vento, R; Giuliano, M; Cantoro, G

doi:10.1007/BF01949733

D-Glucosamine markedly inhibits thymidine incorporation into the TCA-insoluble fraction and thymidine kinase activity in HeLa cells. Both the inhibitory effects are also observed in isolated retinas of chick embryos. In this case the inhibitory effects are age-dependent and the magnitude of the responses decreases with embryonic development. In addition the time of exposure to D-glucosamine which is necessary to reveal the inhibitory effect on thymidine kinase increases with the age of the embryos.

Tesoriere, G., Tesoriere, L., Vento, R., Giuliano, M., & Cantoro, G. (1984). The inhibitory effect of D-glucosamine on thymidine kinase in chick embryo retinas and HeLa cells. EXPERIENTIA, 40(7), 705-707 [10.1007/BF01949733].

Data di pubblicazione:	1984
Titolo:	The inhibitory effect of D-glucosamine on thymidine kinase in chick embryo retinas and HeLa cells
Autori:	TESORIERE, G TESORIERE, Luisa VENTO, Renza GIULIANO, Michela CANTORO, G. mostra contributor esterni nascondi contributor esterni
Citazione:	Tesoriere, G., Tesoriere, L., Vento, R., Giuliano, M., & Cantoro, G. (1984). The inhibitory effect of D-glucosamine on thymidine kinase in chick embryo retinas and HeLa cells. EXPERIENTIA, 40(7), 705-707 [10.1007/BF01949733].
Rivista:	EXPERIENTIA
Digital Object Identifier (DOI):	http://dx.doi.org/10.1007/BF01949733
Abstract:	D-Glucosamine markedly inhibits thymidine incorporation into the TCA-insoluble fraction and thymidine kinase activity in HeLa cells. Both the inhibitory effects are also observed in isolated retinas of chick embryos. In this case the inhibitory effects are age-dependent and the magnitude of the responses decreases with embryonic development. In addition the time of exposure to D-glucosamine which is necessary to reveal the inhibitory effect on thymidine kinase increases with the age of the embryos.
Settore Scientifico Disciplinare:	Settore BIO/10 - Biochimica
Appare nelle tipologie:	1.01 Articolo in rivista

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http://hdl.handle.net/10447/65956

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