The effects of alcohol have been widely studied during the past century, corroborating the idea that this tiny chemical compound acts throughout most of our neurotransmitter systems since it is capable of inducing addictive behaviour. Two of the most serious problems of alcohol addiction are craving and relapse; several studies have demonstrated that relapse is related to the anxious state which occurs during withdrawal, and it has been proved that this behavioural modifications results from an alteration of the dopaminergic and serotonergic systems. An important role in the neurobiology of alcohol addiction is played by acetaldehyde (ACD), ethanol first metabolite.

Cannizzaro, C., Plescia, F., Cacace, S. (2011). Role of acetaldehyde in alcohol addiction: current evidence and future perspectives. MALTA MEDICAL JOURNAL, 23(3).

Role of acetaldehyde in alcohol addiction: current evidence and future perspectives

CANNIZZARO, Carla;PLESCIA, Fulvio;CACACE, Silvana
2011-01-01

Abstract

The effects of alcohol have been widely studied during the past century, corroborating the idea that this tiny chemical compound acts throughout most of our neurotransmitter systems since it is capable of inducing addictive behaviour. Two of the most serious problems of alcohol addiction are craving and relapse; several studies have demonstrated that relapse is related to the anxious state which occurs during withdrawal, and it has been proved that this behavioural modifications results from an alteration of the dopaminergic and serotonergic systems. An important role in the neurobiology of alcohol addiction is played by acetaldehyde (ACD), ethanol first metabolite.
Settore BIO/14 - Farmacologia
Cannizzaro, C., Plescia, F., Cacace, S. (2011). Role of acetaldehyde in alcohol addiction: current evidence and future perspectives. MALTA MEDICAL JOURNAL, 23(3).
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/64260
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