AimTo assess the mortality rate and the use of palliative sedation (PS) in an advanced long-standing acute palliative care unit (APCU)MethodsThe charts of patients who died and eventually received PS, consecutively admitted to the APCU for 4 years, were reviewed. Patients' characteristics and symptom intensity were recorded at admission, 3 days before death and the day before death (T0, T-3, T-end, respectively). For patients who were administered midazolam for PS, initial and final doses of drugs, as well as duration of PS until death, were recorded.ResultsOne hundred and forty-eight patients died in APCU (8.9%), and 45 of them (30.4%) received PS. Younger patients and those reporting high levels of dyspnoea at T-3 and T-end were more likely to be sedated (p=0.002, p=0.013 and 0.002, respectively). The mean duration of PS was 27.47 hours. Mean initial and final doses of midazolam were 35.45 mg/day (SD 19.7) and 45.57 mg/day (SD 20.6), respectively (p=0.001).ConclusionMortality rate in APCU was very low. As a percentage of the number of deaths, PS rate was similar to that reported in other settings. PS does not seem to accelerate impending death.

Mercadante, S., Lo Cascio, A., Casuccio, A. (2023). Mortality rate and palliative sedation in an acute palliative care unit. BMJ SUPPORTIVE & PALLIATIVE CARE [10.1136/spcare-2023-004669].

Mortality rate and palliative sedation in an acute palliative care unit

Casuccio, Alessandra
Ultimo
2023-12-28

Abstract

AimTo assess the mortality rate and the use of palliative sedation (PS) in an advanced long-standing acute palliative care unit (APCU)MethodsThe charts of patients who died and eventually received PS, consecutively admitted to the APCU for 4 years, were reviewed. Patients' characteristics and symptom intensity were recorded at admission, 3 days before death and the day before death (T0, T-3, T-end, respectively). For patients who were administered midazolam for PS, initial and final doses of drugs, as well as duration of PS until death, were recorded.ResultsOne hundred and forty-eight patients died in APCU (8.9%), and 45 of them (30.4%) received PS. Younger patients and those reporting high levels of dyspnoea at T-3 and T-end were more likely to be sedated (p=0.002, p=0.013 and 0.002, respectively). The mean duration of PS was 27.47 hours. Mean initial and final doses of midazolam were 35.45 mg/day (SD 19.7) and 45.57 mg/day (SD 20.6), respectively (p=0.001).ConclusionMortality rate in APCU was very low. As a percentage of the number of deaths, PS rate was similar to that reported in other settings. PS does not seem to accelerate impending death.
28-dic-2023
Mercadante, S., Lo Cascio, A., Casuccio, A. (2023). Mortality rate and palliative sedation in an acute palliative care unit. BMJ SUPPORTIVE & PALLIATIVE CARE [10.1136/spcare-2023-004669].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/638372
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