Systemic lupus erythematosus (SLE) is a serious multisystem disease with a variety of cutaneous and oral manifestations. It is an autoimmune disorder whereby patients develop autoantibodies to many of their cells, cell components, and tissue. The microvascular changes in SLE play a role in the pathogenesis of this disease. The aim of this study was to investigate the gingival microcirculation in SLE patients. METHOD AND MATERIALs: Fifteen SLE patients and 15 healthy subjects were recruited for this study. Gingival microcirculation was investigated using videocapillaroscopy, a noninvasive technique that permits the in vivo evaluation of microvascular patterns. RESULTS: Significant differences between patients and controls for the capillary density were seen. An increase of mean capillary density was observed in SLE patients (105.5 ± 3.41) (P < .05). CONCLUSION: This study showed significant modifications of gingival microcirculation in SLE patients.

Scardina, G.A., Messina, P. (2012). Increased gingival blood vessel density in SLE patients. QUINTESSENCE INTERNATIONAL, 43, 511-515.

Increased gingival blood vessel density in SLE patients

SCARDINA, Giuseppe Alessandro;MESSINA, Pietro
2012-01-01

Abstract

Systemic lupus erythematosus (SLE) is a serious multisystem disease with a variety of cutaneous and oral manifestations. It is an autoimmune disorder whereby patients develop autoantibodies to many of their cells, cell components, and tissue. The microvascular changes in SLE play a role in the pathogenesis of this disease. The aim of this study was to investigate the gingival microcirculation in SLE patients. METHOD AND MATERIALs: Fifteen SLE patients and 15 healthy subjects were recruited for this study. Gingival microcirculation was investigated using videocapillaroscopy, a noninvasive technique that permits the in vivo evaluation of microvascular patterns. RESULTS: Significant differences between patients and controls for the capillary density were seen. An increase of mean capillary density was observed in SLE patients (105.5 ± 3.41) (P < .05). CONCLUSION: This study showed significant modifications of gingival microcirculation in SLE patients.
Settore MED/28 - Malattie Odontostomatologiche
Scardina, G.A., Messina, P. (2012). Increased gingival blood vessel density in SLE patients. QUINTESSENCE INTERNATIONAL, 43, 511-515.
File in questo prodotto:
File Dimensione Formato  
qi_2012_06_s0511.pdf

Solo gestori archvio

Descrizione: full text
Dimensione 192.73 kB
Formato Adobe PDF
192.73 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/63588
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 3
  • ???jsp.display-item.citation.isi??? 4
social impact