Systemic lupus erythematosus (SLE) is a serious multisystem disease with a variety of cutaneous and oral manifestations. It is an autoimmune disorder whereby patients develop autoantibodies to many of their cells, cell components, and tissue. The microvascular changes in SLE play a role in the pathogenesis of this disease. The aim of this study was to investigate the gingival microcirculation in SLE patients. METHOD AND MATERIALs: Fifteen SLE patients and 15 healthy subjects were recruited for this study. Gingival microcirculation was investigated using videocapillaroscopy, a noninvasive technique that permits the in vivo evaluation of microvascular patterns. RESULTS: Significant differences between patients and controls for the capillary density were seen. An increase of mean capillary density was observed in SLE patients (105.5 ± 3.41) (P < .05). CONCLUSION: This study showed significant modifications of gingival microcirculation in SLE patients.

Scardina, G.A., Messina, P. (2012). Increased gingival blood vessel density in SLE patients. QUINTESSENCE INTERNATIONAL, 43, 511-515.

Increased gingival blood vessel density in SLE patients

SCARDINA, Giuseppe Alessandro;MESSINA, Pietro
2012-01-01

Abstract

Systemic lupus erythematosus (SLE) is a serious multisystem disease with a variety of cutaneous and oral manifestations. It is an autoimmune disorder whereby patients develop autoantibodies to many of their cells, cell components, and tissue. The microvascular changes in SLE play a role in the pathogenesis of this disease. The aim of this study was to investigate the gingival microcirculation in SLE patients. METHOD AND MATERIALs: Fifteen SLE patients and 15 healthy subjects were recruited for this study. Gingival microcirculation was investigated using videocapillaroscopy, a noninvasive technique that permits the in vivo evaluation of microvascular patterns. RESULTS: Significant differences between patients and controls for the capillary density were seen. An increase of mean capillary density was observed in SLE patients (105.5 ± 3.41) (P < .05). CONCLUSION: This study showed significant modifications of gingival microcirculation in SLE patients.
2012
Scardina, G.A., Messina, P. (2012). Increased gingival blood vessel density in SLE patients. QUINTESSENCE INTERNATIONAL, 43, 511-515.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/63588
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