Fifty-one children with Mediterranean spotted fever (MSF) were randomized to receive either clarithromycin, 15 mg/kg/day orally in 2 divided doses, or chloramphenicol, 50 mg/kg/day orally in 4 divided doses, for 7 days. Mean time to defervescence was 36.7 h in the clarithromycin group and 47.1 h in the chloramphenicol group (P=.047). Clarithromycin could be an acceptable therapeutic alternative to chloramphenicol and to tetracyclines for children aged <8 years with MSF

Cascio, A., Colomba, C., Di Rosa, D., Salsa, L., di Martino, L., TITONE LANZA DI SCALEA, L. (2001). Efficacy and safety of clarithromycin as treatment for Mediterranean spotted fever in children: a randomized controlled trial. CLINICAL INFECTIOUS DISEASES, 33(3), 409-411.

Efficacy and safety of clarithromycin as treatment for Mediterranean spotted fever in children: a randomized controlled trial

CASCIO, ANTONIO;COLOMBA, Claudia;TITONE LANZA DI SCALEA, Lucina
2001-01-01

Abstract

Fifty-one children with Mediterranean spotted fever (MSF) were randomized to receive either clarithromycin, 15 mg/kg/day orally in 2 divided doses, or chloramphenicol, 50 mg/kg/day orally in 4 divided doses, for 7 days. Mean time to defervescence was 36.7 h in the clarithromycin group and 47.1 h in the chloramphenicol group (P=.047). Clarithromycin could be an acceptable therapeutic alternative to chloramphenicol and to tetracyclines for children aged <8 years with MSF
Cascio, A., Colomba, C., Di Rosa, D., Salsa, L., di Martino, L., TITONE LANZA DI SCALEA, L. (2001). Efficacy and safety of clarithromycin as treatment for Mediterranean spotted fever in children: a randomized controlled trial. CLINICAL INFECTIOUS DISEASES, 33(3), 409-411.
File in questo prodotto:
File Dimensione Formato  
Efficacy and Safety of Clarithromycin.pdf

accesso aperto

Dimensione 65.99 kB
Formato Adobe PDF
65.99 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/63391
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 49
  • ???jsp.display-item.citation.isi??? 37
social impact