Electrochemical analysis of rationally designed ZnO nanostructures for biodegradable cellular scaffolds

This work shows a preliminary analysis of a wet-chemistry synthesized platform based on ZnO nanostructures (n-ZnO) for application in regenerative medicine. n-ZnO stability is investigated by electrochemical in-situ sensing of zinc ions released by n-ZnO soaked in simulated biofluids. Impedance analysis allows detecting subtle changes in the bulk solutionimpedance in the range 1 Hz-50 kHz, which can be ascribed to the release of ionic species in solution, among which Zn2+ ions. In parallel, a voltammetry analysis by low-cost mercury-free screen-printed sensors shows the release of Zn2+ ions at not harmful concentrations.