Circulating histones have been suggested as critical mediators and potential diagnostic/prognostic markers in several hyperinflammatory diseases, including Sars-CoV-2 infection and classical bacterial sepsis, because their levels increase with the worsening of classical and viral sepsis
Giglio, R.V., Ligi, D., Della Franca, C., Lo Sasso, B., Rivas, J.Z., Agnello, L., et al. (2023). Thrombocytopenia and hyperinflammation are induced by extracellular histones circulating in blood. CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 61(12), e239-e243 [10.1515/cclm-2023-0590].
Thrombocytopenia and hyperinflammation are induced by extracellular histones circulating in blood
Giglio, Rosaria VincenzaCo-primo
;Lo Sasso, Bruna;Agnello, Luisa;Ciaccio, MarcelloCo-ultimo
2023-06-21
Abstract
Circulating histones have been suggested as critical mediators and potential diagnostic/prognostic markers in several hyperinflammatory diseases, including Sars-CoV-2 infection and classical bacterial sepsis, because their levels increase with the worsening of classical and viral sepsis
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